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SwRI and St. Mary’s University Partner to Forecast Durability of Metal Hydride Hydrogen Storage

24 June 2026 at 16:21

Southwest Research Institute (SwRI) and St. Mary’s University have embarked on a groundbreaking collaboration aimed at revolutionizing the future of hydrogen storage technology. This joint venture seeks to develop a comprehensive, physics-based forecasting tool capable of predicting the degradation and long-term durability of titanium-iron (TiFe)-based metal hydride vessels. Leveraging a chemical and thermo-mechanical modeling framework, the project represents a significant leap forward in tackling one of the most persistent challenges in hydrogen storage materials science. This initiative is made possible through a $125,839 grant from the St. Mary’s-SwRI Technology and Applied Research (S²TAR) Program, designed to foster impactful research collaborations.

Metal hydrides are pivotal materials in the hydrogen energy landscape, serving as one of the few safe and compact solid-state options for hydrogen storage. These materials function by chemically binding hydrogen to metal lattices through chemisorption, effectively locking hydrogen atoms within the structure. Unlike high-pressure gaseous tanks or cryogenic liquid hydrogen storage, metal hydrides offer improved safety profiles and reduce energy-intensive requirements. However, despite these advantages, their widespread application is hindered by their limited durability and performance degradation resulting from repeated hydrogen absorption and desorption cycles.

At the heart of this ambitious research endeavor is the intricate problem of metal hydride vessel degradation. Over numerous charge and discharge cycles, physical changes ensue within the alloy powders comprising the metal hydride bed. These changes include fracturing of particles, densification of the powder bed, and mechanical stresses that collectively impair hydrogen storage capacity and vessel performance. Traditional evaluation methods rely heavily on prolonged, costly experimental testing to assess long-term vessel integrity—a bottleneck that impedes innovation and commercialization.

The project team, headed by Dr. Richard S. Fu of SwRI and Dr. Mohamed Shaat of St. Mary’s University, seeks to transcend these limitations by integrating advanced physics-based simulations with targeted experimental validation. This dual approach aims to create a robust modeling framework capable of forecasting the lifecycle and operational durability of TiFe metal hydride vessels. The predictive tool will account for the coupled chemical, thermal, and mechanical phenomena driving hydrogen cycling performance over hundreds or even thousands of cycles.

Dr. Shaat is spearheading the development of an intricate, multiphysics computational framework at St. Mary’s University. This model is designed to encapsulate the complex interplay between hydrogen diffusion, chemisorption reactions, phase transformations within the metal hydride, heat generation and transfer, and the evolution of mechanical stress within the vessel. By accurately simulating these interconnected processes, the framework seeks to facilitate precise performance predictions, while also identifying design parameters and operational regimes that optimize both efficiency and vessel longevity.

Central to the team’s vision is the translation of fundamental physical and chemical principles of hydrogen interaction into computationally efficient predictive models. Dr. Shaat emphasizes the importance of capturing the coupling mechanisms—particularly how hydrogen transport influences thermal and mechanical responses and vice versa—in order to provide reliable simulations that replace and reduce the dependence on lengthy physical testing. This innovative approach promises to significantly reduce costs, accelerate development cycles, and improve hydrogen storage system designs.

On the experimental front, SwRI’s team, under Dr. Fu’s guidance, is undertaking controlled, long-term cycling experiments to collect essential validation data. By subjecting metal hydride vessels to realistic charge-discharge scenarios, they aim to quantitatively monitor performance degradation mechanisms as they unfold. These experiments will provide the empirical backbone necessary to calibrate and refine the modeling framework, ensuring that simulation outputs faithfully represent real-world behavior under operational conditions.

The synergy between modeling efforts and experiments forms the cornerstone of the project’s iterative design loop. As Dr. Fu explains, modeling insights will direct the focus of experimental tests to critical phenomena, while the resulting data will feedback to correct and enhance the models. This dynamic interplay is expected to unravel previously obscure degradation mechanisms by illuminating the coupled chemical, thermal, and mechanical interactions at work within the metal hydride vessels. Ultimately, this feedback-driven methodology will yield a predictive tool capable of guiding material improvements and engineering decisions.

Hydrogen’s emergence as a clean, versatile energy carrier is a key cornerstone of global efforts to decarbonize energy and transportation sectors. However, to fulfill its potential, advances in storage technology are imperative. Unlike batteries or fossil fuels, hydrogen storage demands novel materials and engineering solutions due to its unique physical and chemical characteristics. By focusing on metal hydride vessels, this project addresses a promising yet underdeveloped storage pathway that could unlock safer, more efficient hydrogen deployment across diverse applications.

The S²TAR funding mechanism plays an instrumental role in enabling this interdisciplinary collaboration by providing seed resources that draw on the expertise strengths of both SwRI and St. Mary’s University. This partnership is not only poised to produce high-impact scientific outcomes but also lays the foundation for sustained cooperation. Through this collaboration, the team is well-positioned to attract larger external funding sources from federal agencies and industry players focused on advancing hydrogen infrastructure and clean energy technology.

As work progresses, the team anticipates that their predictive modeling tool will be an invaluable resource for the hydrogen storage community. It will offer designers and researchers an evidence-based platform to evaluate new materials, optimize vessel designs, and predict operational lifetimes with higher confidence. By systematically addressing the core durability challenges of metal hydride storage, this project represents a wide-reaching advancement that could significantly accelerate solid-state hydrogen storage adoption worldwide.

In conclusion, this joint initiative by Southwest Research Institute and St. Mary’s University epitomizes the cutting edge of hydrogen storage research. Through combining rigor in experimental validation and sophistication in physics-based modeling, the project champions a future where hydrogen is stored more safely and efficiently. The knowledge generated here promises to not only rewrite the fundamentals of storage vessel degradation understanding but also to catalyze practical applications in the global hydrogen economy.


Subject of Research: Physics-based modeling and experimental validation of TiFe-based metal hydride hydrogen storage vessel degradation and durability.

Article Title: Advancing Solid-State Hydrogen Storage: Predictive Modeling and Experimental Synergy for Metal Hydride Vessel Durability

News Publication Date: June 24, 2026

Web References: https://www.swri.org/markets/energy-environment/power-generation-utilities/advanced-power-systems/hydrogen-energy-research?&utm_medium=referral&utm_source=eurekalert!&utm_campaign=s2tar-metal-hydrides-pr

Image Credits: Southwest Research Institute

Keywords

Hydrogen storage, metal hydrides, TiFe alloys, chemisorption, physics-based modeling, thermo-mechanical framework, hydrogen diffusion, phase transformation, performance degradation, solid-state hydrogen storage, experimental validation, multiphysics simulations

21 Prime Day deals Verge readers are buying right now

24 June 2026 at 16:15
The new Amazon Kindle Paperwhite Signature Edition compared to the Amazon Kindle Colorsoft.
A lot of readers are buying all kinds of Kindles. | Photo by Andrew Liszewski / The Verge

There are an overwhelming number of Prime Day deals to sort through, which is why we spend so much time highlighting products we’ve already tested and can stand behind. But our recommendations are only one way to identify a worthwhile deal: another is seeing which products fellow Verge readers actually buy.

Below, we’ve rounded up the deals that have resonated most with readers who spend as much time thinking about tech as we do. It’s a great way to see what people actually think is a great deal — and what products everyone has been waiting for a price drop on.

Some of the favorites are exactly what you’d expect, like AirPods and Kindles. Others, like Birdbuddy’s camera-equipped smart bird feeder, were a more surprising. If you’re looking for some shopping inspiration, or are simply curious what your fellow readers have been adding to their carts, here are the products that have proven most popular so far during Prime Day.

Hoto 3.6V Electric Screwdriver Kit Pro

Hoto’s rechargeable screwdriver is ideal for small repairs. It offers three torque modes, a rotational speed of up to 220RPM, and a helpful circular LED to illuminate dark spaces. The durable case also holds all 25 steel bits and an extension bar for getting into hard-to-reach places.

Where to Buy:

AirPods Max 2

Apple’s over-ears retain the premium design of the original while delivering improved sound quality and better noise cancellation. They also sport Apple’s H2 chip, which enables newer features like live translation. Read our review.

Where to Buy:

Birdbuddy Pro (solar)

Birdbuddy’s charming, camera-equipped feeder identifies and snaps shots of each bird that stops by, supplementing its 5-megapixel stills with insightful facts via an app. The solar roof helps keep the camera’s battery topped up even when it’s cloudy outside.

Where to Buy:

Amazon Kindle Colorsoft Essentials Bundle

Amazon’s Kindle Colorsoft Signature Edition offers 32GB of storage, supports wireless charging, and has an auto-adjusting front light. The bundle includes a leather cover, and a wireless charging dock. Read our review.
A photo of a person holding a Kindle Colorsoft Signature Edition.

Where to Buy:

Apple Watch SE 3

The Apple Watch SE 3 is a major glow-up, adding an always-on display, wrist-temperature sensor, a more powerful processor, and fast charging. Read our review.

Where to Buy:

SwitchBot Smart Switch Button Pusher

If you’ve ever wished you had a robot that could push a button for you, that’s precisely what SwitchBot’s Smart Switch does. It’s simple, smart, and works on anything with a button. Stick it on the device you want to turn on or off, and you’re set.

Where to Buy:

Aqara Smart Lock U400

This innovative new smart lock uses the U1 ultra-wideband (UWB) chip in many iPhones and Apple Watches to automatically unlock your door as you approach. It will also work with the new Aliro standard and be compatible with Android phones for hands-free unlocking.

Where to Buy:

Belkin Charging Case for Nintendo Switch 2

The case features an integrated power bank and a small pocket to stow an AirTag (or other similarly sized Bluetooth tracker).

Where to Buy:

Fitbit Ace LTE

The Fitbit Ace LTE is a fitness tracker designed specifically for kids, one loaded with movement-based games that encourage physical activity. It also supports GPS location tracking, as well as the ability to send messages and place calls to a limited number of contacts. However, keep in mind that a Fitbit Ace Pass subscription ($9.99 per month / $119.99 per year) is required for location tracking, messaging, and access to the Fitbit Arcade. Read our hands-on impressions.
The Fitbit Ace LTE worn on a wrist.

Where to Buy:

Apple AirTags (second-generation)

Apple’s latest AirTag features an upgraded ultra-wideband chip for more precise location tracking, a noticeably louder speaker, and an expanded Bluetooth range. Read our review.

Where to Buy:

AirPods Pro 3

The AirPods Pro 3 have a new design that improves their fit, superior noise cancellation, better bass, and fairly accurate heart rate sensors. Read our review.
Hands holding the open case for the AirPods Pro 3 above multi-colored books on a wooden table.

Where to Buy:

Glocusent Book Light

Glocusent’s bendable neck light supports three color temperatures and six levels of brightness. It’s rechargeable via USB-C and can last up to 80 hours per charge.

Where to Buy:

Belkin BoostCharge Pro 3-in-1 Wireless Charging Stand with Qi2 15W

Belkin’s triple charging stand achieves 15W MagSafe wireless iPhone charging speeds and keeps your phone and Apple Watch elevated for easy reading.

Where to Buy:

Anker Laptop Power Bank

Anker’s 25,000mAh power bank sports two built-in USB-C cables (one of which is retractable), plus one USB-C and USB-A port. It tops out at 165W when charging two devices simultaneously, or 130W when charging three or four.

Where to Buy:

Kindle Paperwhite (12th-gen)

Amazon’s latest Kindle Paperwhite — aka our favorite ebook reader — is waterproof, has a seven-inch display, and lasts weeks per charge. Read our review.
The 2024 Kindle Paperwhite.

Where to Buy:

Google Nest Wifi Pro

The Nest Wifi Pro is an upgraded version of the standard model, and it’s equipped with Matter and Thread support in addition to Wi-Fi 6E connectivity. 
White Google Nest Wifi Pro router on a white table in front of a window.

Where to Buy:

Google TV Streamer (4K)

Google’s terrific TV Streamer (4K) is the company’s best attempt at a streaming device yet, with built-in ethernet, an excellent interface, and smart home compatibility with both Matter and Thread. Read our review.
A marketing image of the Google TV Streamer.

Where to Buy:

Google Nest Wifi Pro

The Nest Wifi Pro is an upgraded version of the standard model, and it’s equipped with Matter and Thread support in addition to Wi-Fi 6E connectivity. 
White Google Nest Wifi Pro router on a white table in front of a window.

Where to Buy:

Ninja Creami Deluxe 11-in-1 Ice Cream Maker

It’s time to fill that freezer with ice cream, but not just any ice cream will do. Make the flavors you want, complete with experimental mix-ins, with Ninja’s Creami Deluxe.

Where to Buy:

Kindle Paperwhite Signature Edition

The premium Kindle Paperwhite Signature Edition offers the same design and performance as the standard model but with more storage and support for wireless charging.
The Amazon Kindle Paperwhite Signature Edition (2024) displaying a page of text sitting on an open book.

Where to Buy:

SwitchBot Standing Circulator Fan

A quiet, battery-powered fan that moves a lot of air despite its small size, the Switchbot Standing Circulator is a surprisingly versatile smart home addition.

Where to Buy:

Laptop prices suck these days, but here are 25 Prime Day deals that help a little

A rear-view of the 15-inch MacBook Air M5.

The RAM, storage, and component crunch has come for new laptop prices. Plenty of models have gone up in price after being on the market for months, and so have those that’ve been on shelves for over a year. Plus, many new models are releasing at higher prices than the previous generation. So, it really isn’t the best time to buy a new laptop. But what if you need one or really want one now, and you prefer to shop new?

Well, I’m not here to tell you that Amazon’s Prime Day makes everything better. But the discounts certainly don’t hurt.

As usual, we’re doing our best to surface the best Prime Day tech deals. And here, we’ve pulled together the biggest discounts happening not just on laptops, but also on keyboards, mice, webcams, or other worthwhile PC accessories. And since Prime Day has counter-deals running at other retailers like Best Buy (and its Tech Fest Sale), there are also laptop deals for non-Amazon shoppers alike.

The best deals on MacBooks

  • The days of multi-hundred-dollar discounts on MacBooks are behind us for now, but the base 14-inch MacBook Pro with an M5 chip for $1,549 ($150 off) at Amazon and Best Buy is still a solid deal. It’s powerful enough for the average content creator, comes with 16GB of RAM and 1TB of storage, and has lots of ports. Read our review.

Apple MacBook Air (M5)

Apple’s 2026 MacBook Air has an M5 chip and starts with 512GB of storage that’s significantly faster than previous generations. It’s still as excellent as ever despite a higher base price. Read our review.

Where to Buy:

  • The 14-inch MacBook Pro with an M5 Pro chip (15-core CPU / 16-core GPU), 24GB of memory, and 1TB of storage is $2,034 (around $165 off) at Amazon and $2,049 at Best Buy. It’s a pretty nice step-up model from the standard M5 MacBook Pro, with a bit more RAM, a more powerful chip, and faster Thunderbolt 5 ports.

The best deals on Windows laptops

Microsoft Surface Laptop, 13-inch

Microsoft’s slightly smaller, entry-level Surface Laptop trims some of the size and a few features from its bigger 13.8-inch counterpart, but it maintains excellent battery life and solid performance. It’s just a shame it’s price went up. Read our review.

Where to Buy:

Microsoft Surface Pro 12-inch

Microsoft’s latest Surface Pro is smaller, with a new design and updated keyboard. It’s powered by Qualcomm’s Arm64 Snapdragon X Plus chip. Read our review.

Where to Buy:

  • The Lenovo IdeaPad Slim 3x was one of the laptops I tested against the MacBook Neo and… it got smoked. But a 512GB config for $449 ($251 off) at Walmart? Not bad. The speakers are an assault on your ears and the trackpad ain’t great, but if you can live with those shortcomings, you get a decent laptop with a competent Snapdragon X processor and marathon battery life. Just read our review and be aware of its shortcomings.
  • Like the Lenovo above, the Acer Aspire 14 AI is another MacBook Neo contender I tested that’s on sale. It’s $589.99 (about $288 off) at Amazon, exclusively for Prime members. Best Buy has it for anyone, sold via Acer, for $599.99. Let me set your expectations: The screen on this laptop is pretty washed out, the speakers are tinny, and the build quality feels cheap. But what you’re getting a deal on is a great Intel Core Ultra 7 256V “Lunar Lake” processor that’s a solid performer while also being quite power efficient. It also has plenty of ports (including Thunderbolt 4) and can even do some light gaming.
  • For a higher-end Acer offering, the Swift X 14 AI is selling for a new low of $1,559.99 ($140 off) at Amazon for Prime members. The 14-inch laptop has a 2880 x 1800 / 120Hz OLED, AMD Ryzen AI 7 350 CPU, RTX 5060 discreet graphics, 32GB of RAM and 1TB SSD. It even has a haptic trackpad that should be a nice upgrade over Acer’s mechanical ones that can be a bit basic.

Asus Zenbook A14

Asus’s Zenbook A14 is a bit of a MacBook Air wannabe, but it’s a compelling alternative if you value a superlight Windows laptop with long battery life. The last-gen 2025 model sports an Arm-based Qualcomm Snapdragon X Plus chip, a nice 14-inch OLED display, and a sleek textured beige finish.

Where to Buy:

The best deals on gaming laptops

2025 Asus ROG Zephyrus G14

Asus’ ROG Zephyrus G14 is the go-to choice for a portable gaming machine that’s great at regular laptop duties. It’s got a lovely OLED display, great keyboard and trackpad, and solid battery life. There’s a new Intel model that’s much pricier, but the 2025 version with AMD chips is still a great choice.

Where to Buy:

  • The 2025 Asus ROG Zephyrus G16 is $1,574.99 ($575 off) at Best Buy. The larger version of the Zephyrus twins sports a 240Hz OLED display and a thin profile to make it travel friendly. This configuration includes an Intel Core Ultra 9 285H CPU, RTX 5070 GPU, 16GB of RAM, and 1TB SSD.
  • HP’s Omen 16 gaming laptop from last year is $1,619.99 ($600 off) at Best Buy through a third-party seller. The 16-inch laptop is configured with an AMD Ryzen 9 8940HX processor, RTX 5060 graphics, 32GB of RAM, and 1TB SSD. Not bad for around $1,500, but while its screen’s 144Hz refresh is nice, the resolution is only 1920 x 1200.
  • For a little more money, you can get a Lenovo Legion 5i at Walmart for $1,589 ($261 off). This 15-inch Legion has an Intel Core i9 14900HX CPU, RTX 5070 GPU (the 8GB VRAM version), 16GB of RAM, and 1TB SSD. You’re getting less RAM than the HP Omen deal, but in exchange it’s got a better GPU and 2560 x 1600 OLED display with 165Hz refresh rate.

Acer Predator Helios Neo 16 AI (2025)

An affordable mid-ranger from Acer running RTX 5070 or 5070 Ti graphics, a 16-inch 240Hz display, and lots of ports.

Where to Buy:

  • Acer’s Nitro V 16S AI gaming laptop is selling for $1,099.99 ($300 off) at Amazon, exclusively for Prime members. It’s got an AMD Ryzen 7 260 CPU, RTX 5060 GPU, 32GB of RAM, and 1TB SSD. The specs are close to the Asus ROG Zephyrus G14 deal above, but it’s much chunkier, has more RAM, and its display is larger but a lower-res LCD.

The best deals on keyboards, mice, and other PC peripherals

  • Moft has a variety of deals on its origami-style cases and stands. You can get its folding 2-in-1 Laptop Carry Sleeve, a sleek laptop case that doubles as a portable stand, for $51.96 ($13 off) at Amazon in four sizes and up to 11 different colors. Or, if you don’t mind some adhesive, the Moft Laptop Stand in select colors is $19.99 ($5 off) at Amazon. The super thin attachment sticks to the bottom of your laptop to give you a fold-out stand anywhere you go.

Logitech MX Master 3S

The MX Master 3S is a favorite among many Verge staff members because of its comfort and customization. It can connect via Bluetooth, via its included 2.4GHz receiver, or wired with its USB-C cable.

Where to Buy:

  • The fairly new Keychron V5 Ultra mechanical keyboard with Silk POM red linear switches is $107.99 ($12 off) at Amazon. The near-full-size 96-percent layout board has an incredibly long battery life thanks to its ZMK-based firmware, and it supports a fast 8,000Hz polling rate via its 2.4GHz wireless connection. Its plastic case isn’t as nice as ones with a metal chassis, but it’s a great no-nonsense keyboard for the money. Read our review.
  • Ugreen’s Dock and Stand for the Mac Mini M4 / M4 Pro is $49.99 ($40 off) at Amazon, exclusively for Prime members. The dock sits below your Mac Mini and plugs in to a rear USB-C port, dramatically expanding the port offerings of your tiny desktop and making your power button more accessible with a tiny lever. It has SD / microSD card slots and two USB-A ports on the front, and three USB-C and three USB-A ports on the rear. Plus, inside is an M.2 SSD slot for extra built-in storage. (You’ll have to BYO SSD.)
  • LG’s 32-inch UltraGear 32GX850A-B OLED gaming monitor is $684.50 ($600 off MSRP) at Amazon, exclusively for Prime members. LG also has it for anyone for a slightly higher $699.99. The dual mode 4K OLED supports a fairly high 165Hz refresh rate but can dip down to 1920 x 1080 resolution to output a super fast 330Hz for specialized uses like competitive gaming.
  • For a much more affordable and down to Earth OLED, check out the 27-inch Acer Predator Gaming Monitor X27U, selling for $314.99 ($235 off) at Amazon, exclusively for Prime members. It’s a sweet spot of 2560 x 1440 resolution that isn’t as demanding on games while supporting a high 240Hz refresh.

Elgato Stream Deck MK. 2

The MK.2 version of the standard Stream Deck comes with 15 programmable buttons, a swappable faceplate, and a detachable stand.

Where to Buy:

Asus ROG Falcata

A unique Hall effect gaming keyboard that actually takes ergonomics into account. Read our review.

Where to Buy:

8BitDo Retro 87 Mechanical Keyboard (Xbox Edition)

This mechanical keyboard is inspired by the original Xbox, with a translucent green color scheme and two large customizable buttons. Along with Bluetooth support, it offers a standard tenkeyless layout with clicky hot-swappable Kailh Jellyfish X switches.
8BitDo’s green Xbox-themed Retro 87 Mechanical Keyboard in front of a matching green Xbox console.

Where to Buy:

Update, June 24th: Updated current deals and added new ones for the Microsoft Surface Pro 12-inch and Moft accessories.

Hierarchical Endpoints, Win Stats in Geromedicine Trials

24 June 2026 at 15:17

In the rapidly evolving field of geroscience, the quest to translate scientific breakthroughs into tangible clinical benefits has encountered a formidable obstacle: the challenge of selecting trial outcomes that comprehensively reflect the multifaceted effects of geroprotective interventions while satisfying rigorous clinical and regulatory benchmarks. Despite the surge in research advancing our understanding of aging and potential therapies to extend healthspan, clinical trials often struggle to identify endpoints that are simultaneously robust, feasible, and accepted by regulators. This conundrum has impeded the pace at which promising discoveries transition from the bench to bedside.

Traditional endpoints in clinical trials for aging-related therapies have heavily relied on mortality as the gold standard outcome. Mortality is undeniably objective and resonates with regulatory agencies due to its clear clinical significance. However, using mortality as a primary endpoint is frequently impractical in geromedicine trials. The extended timelines required, the large participant populations needed, and ethical considerations make mortality a difficult measure for many intervention studies focused on aging. Given the complexity and prolonged nature of aging processes, mortality-based outcomes often limit the feasibility of clinical research into interventions designed to slow or reverse age-associated decline.

As an alternative, surrogate measures aimed at capturing the quality of extended life, often termed healthspan, have gained attention. Healthspan encompasses diverse dimensions such as physical function, cognitive performance, and biomarker profiles that collectively reflect an individual’s biological and functional status. These measures present a more practical and nuanced depiction of aging’s trajectory and the impact of geroprotective treatments. Nevertheless, healthspan-related endpoints are frequently regarded as “soft” or indirect, necessitating further validation to convince stakeholders of their reliability and clinical relevance. Their subjective nature and variability introduce challenges in affirming their predictive value and regulatory acceptance.

In response to these challenges, researchers have proposed an innovative methodological framework that seeks to harmonize the strengths of both mortality and healthspan measures while mitigating their respective weaknesses. This novel strategy employs hierarchical composite endpoints analyzed through a time-to-worst-event approach, leveraging win statistics to facilitate a pragmatic and scientifically grounded compromise. The essence of this methodology lies in comparing participant pairs within clinical trials based on a predefined, clinically justified hierarchy of events, prioritizing the most severe and objective endpoints such as mortality and major morbidity.

This hierarchical design assigns differing weights to outcomes positioned along a clinical severity spectrum. At the highest tier reside unequivocal events—death and serious clinical incidents—that carry unquestionable clinical importance and regulatory weight. Subsequent tiers integrate healthspan surrogates and biomarker data, contributing valuable subsidiary information that captures subtler yet meaningful intervention effects. Employing this layered approach enables researchers to reflect a fuller spectrum of aging-related outcomes without compromising the prominence of critical clinical endpoints.

Time-to-worst-event analysis serves as a robust statistical tool within this hierarchical framework. By focusing on the timing of the most severe event experienced by an individual, the methodology ensures that the earliest and most significant detriment determines the outcome classification, encompassing the patient’s clinical journey comprehensively. This time-sensitive lens captures not only whether but also when adverse clinical states manifest, providing a dynamic and nuanced perspective critical for aging-related trials, where the temporal dimension is essential.

Central to the proposed framework is the use of “win statistics,” a comparative metric allowing pairwise analysis of trial participants. This statistical method calculates wins, ties, and losses based on the clinical hierarchy, elucidating the overall treatment effect by aggregating these individual pairwise comparisons. The win statistic’s strength lies in its ability to synthesize multifaceted outcomes into a single interpretable measure while maintaining clinical meaning and relevance. Unlike conventional single-endpoint analyses, this approach acknowledges the multidimensional impact of geroprotective interventions.

Importantly, the selection and ordering of outcomes within this hierarchical system demand rigorous clinical and mechanistic justification. Consensus must be achieved among investigators, clinicians, and regulatory authorities to define which events take precedence and how ties are resolved. This transparent and collaborative process assures that composite endpoint construction reflects true clinical priorities and biological plausibility, bolstering regulatory confidence and facilitating trial approval and interpretation. Such an approach safeguards against arbitrary outcome weighting or biased interpretation.

The implications for the future of geromedicine clinical trials are substantial. By embracing hierarchical composite endpoints and win statistics, researchers can design more efficient trials that capture a broad spectrum of treatment effects within feasible timescales and participant cohorts. This methodology sidesteps the pitfalls of relying solely on mortality, while strengthening the evidentiary value of surrogate endpoints and biomarkers. Consequently, promising geroprotective interventions may undergo more straightforward, cost-effective evaluation, accelerating their clinical translation and potential public health impact.

This innovative design also opens pathways for more personalized assessment of intervention efficacy. By integrating multiple health domains and clinical events, trials can better reflect the heterogeneity of aging populations and diverse therapeutic mechanisms. The nuanced outcome assessment permits differential benefits and risks to be dissected, fostering precision geromedicine. Regulators and clinicians alike stand to gain from richer and more actionable data that truly capture quality-of-life improvements alongside traditional survival metrics.

Moreover, the potential regulatory acceptance of hierarchical composite endpoints could catalyze a paradigm shift in aging-related drug development. As the geroscience community demonstrates the validity and utility of such outcomes, regulators may become more amenable to approving longevity therapeutics supported by multifaceted endpoints rather than awaiting protracted mortality data. This regulatory evolution promises to invigorate investment and innovation in geromedicine, an area of growing importance in the context of expanding elderly populations worldwide.

While promising, this approach also entails challenges. It requires meticulous endpoint definition and standardization, robust statistical modeling expertise, and extensive stakeholder engagement to ensure that composite hierarchies are clinically meaningful and mechanistically grounded. Ensuring reproducibility and cross-trial comparability necessitates development of consensus guidelines and open data standards. Ethical considerations surrounding the relative weighting of life quality versus survival further complicate endpoint formulation and require ongoing discourse.

Nevertheless, the proposed hierarchical endpoint framework with win statistics embodies a timely and much-needed advancement addressing a fundamental bottleneck in geroscience clinical research. By bridging regulatory requirements with scientific insights into aging’s multidimensional nature, it lays a robust foundation for accelerated translation of geroprotective therapies. As the population demographic shift intensifies demand for effective aging interventions, such pioneering statistical and clinical innovation is pivotal in transforming geromedicine from promising science into practical medicine.

The work by Abdellatif, Kim, and Kroemer offers a compelling blueprint for the next generation of geromedicine trials. Their integrative approach thoughtfully balances objectivity, clinical relevance, and feasibility, paving the way for interventions that not only extend lifespan but also enhance the quality of those extended years. The advent of hierarchical composite endpoints guided by win statistics may ultimately revolutionize how aging therapies are evaluated, deployed, and embraced by healthcare systems worldwide, heralding a new era in age-related healthcare.

As this methodology gains traction, collaborative efforts across academia, industry, and regulatory bodies will be critical to refine, validate, and implement hierarchical endpoints in ongoing and future geroscience trials. Real-world application and longitudinal data will provide further insights to optimize outcome hierarchies and better reflect patient-centered benefits. Such collective progress holds the promise to unlock the full potential of geroprotective interventions, reshaping the landscape of aging medicine.

In essence, hierarchical composite endpoints and win statistic analysis emerge as a paradigm-shifting solution to the age-old dilemma of measuring meaningful outcomes in aging research. By embracing complexity and clinical priorities simultaneously, this approach captures the multidimensional health impacts of geromedicine interventions with rigor and pragmatism. The coming years will reveal how this innovation transforms clinical trial design and ultimately delivers on the long-awaited promise of prolonging both lifespan and healthspan.


Subject of Research: Geroscience clinical trial outcome measurement; hierarchical composite endpoints in geromedicine studies; win statistics for multidimensional aging-related outcomes

Article Title: Hierarchical endpoints and win statistics for geromedicine trials

Article References:
Abdellatif, M., Kim, Y. & Kroemer, G. Hierarchical endpoints and win statistics for geromedicine trials. Nat Aging (2026). https://doi.org/10.1038/s43587-026-01158-3

Image Credits: AI Generated

DOI: https://doi.org/10.1038/s43587-026-01158-3

'Weirdos of the sperm whale world' appear to be evolving 2 different dialects, audio recordings suggest

24 June 2026 at 15:01

An isolated population of sperm whales in the Mediterranean Sea are splitting into two distinct groups with different dialects, a new study reveals. This shift has likely been happening for thousands of years, as two groups split from an initial single population.

The findings, published Tuesday (June 23) in the journal Proceedings of the Royal Society B: Biological Sciences, are providing a rare insight into the process of different dialects emerging among non-human species.

The sperm whales (Physeter macrocephalus) live in small social units of females and young, and they associate with other groups in the same area. They use social vocalizations called codas ‪—‬ shortpatterns of clicks ‪—‬ to communicate. The particular codas they use identify them as being part of the same cultural group.

Taylor Hersh, a researcher in the School of Biological Sciences at the University of Bristol in the U.K. and first author of the research, and her colleagues have analyzed codas recorded over almost 20 years in the Mediterranean, where there is a unique population of a few thousand sperm whales, to see if they all use the same dialect.

Sperm whales entered the Mediterranean via the Strait of Gibraltar about 20,000 years ago, and they have spread throughout the area. The whales rarely leave the sea ‪—‬ even males, which normally migrate. Other sperm whales don't seem to enter often, either, so the Mediterranean ones are effectively isolated from other populations and are considered an endangered subpopulation.

"The sperm whales in the Mediterranean are really cool," Hersh told Live Science. "I've always thought of them as the weirdos of the sperm whale world in that they don't leave through the Strait of Gibraltar even though they could. They are unique, and for a long time, they were also thought to be acoustically unique."

The thinking was that all the sperm whales in the Mediterranean belonged to the same clan, identified by their use of a single coda 90% of the time. This coda consists of three clicks and then a pause before the fourth and final click ‪—‬ a pattern called the three-plus-one type.

But the analysis by Hersh's team of 5,291 codas recorded between 2003 and 2021 revealed that sperm whales living in the eastern Mediterranean around the Hellenic Trench, off Greece, have a slightly different dialect from that used by animals in the western basin around Spain's Balearic Islands.

The eastern whales produce a distinct form of the three-plus-one coda. "It's a very similar pattern of clicks, but it's much, much faster," Hersh said.

four sperm whales in the sea

Researchers found distinct dialects between the two populations, with the eastern population producing slower codas. (Image credit: Asociación Tursiops)

In some recordings, whales in the eastern Mediterranean produced the slower coda, showing they were familiar with both dialects.

"The western sperm whales religiously stick to their dialect, but there were four instances of eastern whales using the western dialect," Hersh said. "The question of why is still an open one. Their dialect seems to be a lot more diverse than we expected. They do occasionally make those slow three-plus-one codas, but they make a lot of other coda types, too."

Hersh hopes further recordings alongside records that tie individual whales to sounds and events might help elucidate why the whales switch between dialects.

"It's exciting to see this study showing different populations behaving closely, but also differently," said Gašper Beguš, linguistics lead at Project CETI, a nonprofit organization that aims to translate the communication of sperm whales.

The study paints a picture of sperm whales progressively occupying the Mediterranean from west to east, with the dialect of one group gradually changing. "The groups in the east clearly remember the western dialect because they have these 'throwback' days," Hersh said.

It's still a mystery how and why these dialects evolved.

"Every speech is a dialect; the question is how did they arise and why?" said Beguš, who wasn't involved in the new study. He said the historical change in habitat does help to show which dialect came first. "In the Mediterranean, maybe they're forming different groups, so that's why they're trying to distinguish themselves," he told Live Science, giving the parallel of young people who distinguish themselves from previous generations by coming up with new slang.

"It's possible that these two groups with repertoires that are very similar but still distinctive could represent a sort of midway phase,” Ellen Jacobs, a marine biologist at Aarhus University in Denmark who wasn't involved in the research, told Live Science via email.

"Changes in the rhythm might be a very feasible and meaningful way for coda signals to start to diverge," she said, like the way the English words "How do you do?" got mashed together until they morphed into "howdy."

The timescale on which a sperm whale dialect develops is uncertain, but it's likely a slow process, according to Hersh. "It's probably happening on the scale of hundreds and thousands of years, because sperm whales can live into their 60s and 70s. And this study is looking over 19 years of data, and that's just a snapshot of one animal's life," Hersh said.

This means the eastern whale dialect was conceivably emerging in the Mediterranean Sea as famous human civilizations were speaking different languages on the surrounding lands, including when the ancient Greeks and Romans were rising and then falling.

"Maybe if we could leave them for another 10,000 years, we would come back to find the completely separated dialects of clans," Jacobs said.

19 great Prime Day deals on our favorite charging gear

24 June 2026 at 15:00
An Anker Nano 45W charger plugged into an outlet.

If you’re sick of your devices running out of juice early into the evening just as you’re about to go out, Prime Day is a great time to pick up a new power bank or charging brick. We’ve rounded up the best deals on a range of discounted charging equipment, from power banks and wall chargers that support the latest Qi2 standard to surge protectors with long cords and plenty of ports and adapters for traveling internationally. There’s even a great deal on a Switch 2 zip-up case that includes a battery pack for extending gaming sessions on the go.


Ugreen Nexode Charger with Retractable USB-C Cable

The allure of Ugreen’s 65W Nexode charger is simple: It features a built-in retractable USB-C cable, so you don’t need an extra accessory to charge your gadgets. The cable extends to over 2 feet and securely locks at any length. It also features additional USB-C and USB-A ports, allowing you to charge three devices simultaneously.
The Ugreen Nexode 65W Charger with a retractable USB-C cable floating on a white background.

Where to Buy:

Iniu P55-E2 Power Bank (10,000mAh)

Iniu’s P55-E2 Power Bank is an ultra-slim three-port USB charger that’s capable of fully recharging an iPhone 16 twice. It supports charging speeds of up to 45W via a USB-C port, which can deliver fast recharging for a range of gadgets.
The Iniu P55-E2 power bank next to an iPad, iPhone, and Apple Watch.

Where to Buy:

Baseus PicoGo AM52 Qi2.2 Magnetic Power Bank

The AM52’s MagSafe-ready design means it can snap onto newer iPhones and supply up to 25W of power, and because it has a USB-C port, it can also charge a Nintendo Switch 2 and other electronics.

Where to Buy:

Anker MagGo Power Bank (10K)

Anker’s Qi2-enabled MagGo Power Bank (10K) can supply 15W charging speeds to any MagSafe-compatible iPhone. It also supports wired 27W USB-C charging and comes with an integrated kickstand that lets you prop it up on a desk or nightstand.

Where to Buy:

Anker Laptop Power Bank

Anker’s aptly titled Laptop Power Bank is a lifesaver for anyone who works or studies on the go. With an impressive 25,000mAh capacity and a total output of 165W, it can quickly charge a beefy MacBook Pro to 50 percent capacity in under 30 minutes. Plus, with three USB-C ports and a USB-A port, you can power multiple devices at once, including phones, tablets, and handheld consoles.

Where to Buy:

Belkin 42W Dual Port Charger Block

This compact charging block provides up to 30W via USB-C and 12W over USB-A, with folding prongs that safely stow away for travel and storage.

Where to Buy:

Anker Nano 45W charger with display

Anker’s latest single-port USB-C charger offers up to 45W of power, foldable prongs, and a front-facing “smart display” that lets you see the charge level, power flow, and other useful information at a glance.

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Meross Smart Power Strip (Apple Home)

The excellent Meross Smart Power Strip comes with four sockets and four USB ports, all of which are controllable via Apple Home, Alexa, or Google Home.

Where to Buy:

Anker 351 Power Strip

This substantial Anker power strip has a five-foot cord, 12 AC outlets, a 20W USB-C port, and two USB-A ports, which should be more than enough to charge all of your devices at once.

Where to Buy:

Belkin BoostCharge Pro 3-in-1 Wireless Charging Stand with Qi2 15W

Belkin’s triple charging stand achieves 15W MagSafe wireless iPhone charging speeds and keeps your phone and Apple Watch elevated for easy reading.

Where to Buy:

Anker 555 USB-C hub

This 8-in-1 USB-C hub delivers plenty of connectivity, including ethernet, a 4K / 60Hz-capable HDMI port, microSD / SD card readers, USB-C, and USB-A. It can also power your laptop with up to 85W of power.
Anker 555 USB-C hub

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Anker Nano Travel Adapter (5-in-1, 20W)

Anker’s jack-of-all-trades travel adapter packs enough ports to refill your devices during some downtime. It features one AC outlet, two USB-C ports (one tops out at 20W), and two USB-A ports. It’s not the fastest wall charger, but it’s a solid choice when you can find it at a discount.

Where to Buy:

Belkin Charging Case for Nintendo Switch 2

The case features an integrated power bank and a small pocket to stow an AirTag (or other similarly sized Bluetooth tracker).

Where to Buy:

Belkin UltraCharge Pro 10,000mAh Qi 2.2 power bank with kickstand

Where to Buy:

Ugreen Nexode Charger (200W, 6-Port)

Ugreen’s six-port, 200W charger can replace the two or three smaller power bricks sitting around your office. It’s powerful enough to charge two MacBooks at their top speeds simultaneously, and the three less powerful ports are perfect for charging smaller electronics.
Ugreen's Nexode Charger (200W, 6-Port) connected to two MacBooks and other devices.

Where to Buy:

Anker 20,000mAh 30W Zolo power bank

As it turns out, having a battery pack that can charge your device in a jiffy and double as a lanyard is pretty great.

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Anker 321 USB-A to Lightning Cable (3 ft 3-in-1)

Eliminate clutter with Anker’s 3-in-1 cable, which features interchangeable connectors for micro USB, Lightning, and USB-C.

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Epicka Universal Series Travel Adapter

Epicka’s universal travel adapter is an all-in-one adapter that includes four different plugs that cover over 150 countries.
Travel adaptor on power strip connected to phones and laptop.

Where to Buy:

Ugreen 100W USB-C Cable (two-pack)

These cables from Ugreen are six feet each and support charging speeds of up to 100W, making them a suitable fit for tablets, some laptops, phones, and other portable gear.
ugreen 100w usb-c cable

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Photoreforming Solid Waste with Single-Source Co-Catalysts

24 June 2026 at 14:45

In a groundbreaking development poised to redefine waste management and sustainable energy production, researchers have unveiled a revolutionary method for photoreforming solid waste on an unprecedented 1-square-meter scale. This innovative advance, detailed in the latest issue of Nature Chemical Engineering, leverages single-source precursor-derived co-catalyst films to convert ubiquitous solid waste into valuable chemical fuels, heralding a new era in environmental remediation coupled with renewable energy generation.

At the heart of this innovation lies the principle of photoreforming, a process by which sunlight catalyzes the chemical transformation of organic materials into hydrogen and other energy-rich molecules. Historically limited to small-scale demonstrations and powdered catalysts, this method struggled with scalability and practical application outside controlled laboratory settings. The reported technique shatters these limitations by fabricating robust co-catalyst films derived from a unified precursor source, enabling efficient photoconversion across large surface areas with enhanced stability and performance.

The researchers crafted these functional films through an ingenious synthesis route, where a single molecular precursor simultaneously yields both the active catalytic sites and the supporting matrix. This contrasts with conventional multi-step fabrication approaches that often result in inconsistent catalyst dispersion and energy losses. By integrating the catalyst components at the molecular level, the team ensured homogeneity, maximized photon absorption, and optimized charge separation dynamics, all critical parameters for sustained photocatalytic activity.

Transforming real-world solid waste – encompassing plastics, biomass residues, and mixed refuse – into clean fuels presents a formidable challenge due to their complex chemical compositions and structural heterogeneity. The co-catalyst films demonstrated remarkable versatility and adaptability, efficiently processing these diverse substrates under simulated sunlight without requiring extensive pre-treatment. This robustness signals a significant leap toward practical deployment in municipal waste processing facilities and industrial settings.

The experimental setup encompassed a square meter of coated substrate exposed to controlled illumination, mirroring natural sunlight intensity conditions. Over extended operation, the system consistently yielded high rates of hydrogen and other value-added chemicals, outperforming benchmark photocatalysts by a considerable margin. Importantly, the films manifested remarkable photostability and mechanical adhesion, demonstrating resilience against degradation mechanisms like photo-corrosion and mechanical abrasion that typically afflict photocatalytic layers.

At the nanoscale, characterization techniques revealed uniform distribution of nanosized catalytic domains embedded within a conductive, photoactive matrix. This architecture ensures rapid electron-hole separation and transport, minimizing recombination losses which commonly plague photocatalytic systems and limit hydrogen evolution rates. Spectroscopic analyses corroborated enhanced visible-light absorption, attributed to tailored bandgap engineering achieved during precursor design, broadening the usable solar spectrum beyond ultraviolet wavelengths.

The process design also embraced mass transport optimization, incorporating porous film structures that facilitated effective diffusion of reactants and removal of gaseous products. This morphologic control prevented stagnation zones and concentration gradients, enhancing catalytic turnover and ensuring stable long-term performance. Additionally, the modular film fabrication approach promises scalability and integration into various reactor geometries without compromising catalytic efficiency.

Beyond hydrogen generation, the system also showcased the capacity to produce liquid fuels and chemical feedstocks, capitalizing on selective reaction pathways induced by co-catalyst composition tuning. This selectivity allows tailored conversion routes matching industrial chemical demands, moving beyond mere waste disposal toward circular chemical economies. The dual benefit of environmental waste mitigation coupled with clean energy and chemical synthesis embodies transformative potential for sustainable industrial practices.

Critically, the team emphasized the environmental and economic implications of adopting such technology at scale. By converting problematic solid waste streams into valuable resources using sunlight – a free and abundant energy source – this approach diminishes reliance on fossil fuels and reduces landfill burden. Cost analyses suggested that, once scaled, the technique could rival established catalytic processes in operational expenditure, thus offering an attractive proposition for policymakers and industry leaders aiming to meet stringent environmental targets.

The interdisciplinary collaboration instrumental in achieving this advance integrated expertise across materials chemistry, photophysics, environmental engineering, and nanofabrication. Such synthesis of disciplines underscored the inherent complexity of developing scalable photocatalytic platforms capable of handling real-world waste complexities while maintaining high efficiency and durability.

Looking ahead, the researchers are exploring further enhancements including tandem catalyst layers, optimized co-catalyst configurations, and hybrid photochemical-electrochemical systems to elevate the energy conversion efficiency and broaden substrate compatibility. In parallel, pilot-scale demonstrations are underway to validate system performance in outdoor environments subject to variable weather conditions, pivotal for transitioning laboratory innovation into field applications.

This pioneering work sets a new benchmark in photoreforming science, illustrating how precise molecular engineering and thoughtful system design can transform a pressing global challenge—solid waste accumulation—into a renewable energy opportunity. Its implications resonate strongly with global sustainability aspirations, promising an economically feasible and environmentally benign pathway to simultaneously address climate change mitigation, waste reduction, and clean energy production.

As society grapples with mounting waste generation paired with escalating energy demands, innovations such as these underscore the invaluable role of scientific ingenuity in crafting solutions that are as elegant as they are practical. By harnessing the synergy of sunlight and advanced material chemistry, the future of waste management is illuminated—not as a burden, but as a wellspring of renewable chemical energy.

In summary, this major scientific milestone demonstrates that photoreforming solid waste at a 1 m² scale using single-source precursor-derived co-catalyst films is no longer a theoretical possibility but a tangible technological reality. It unequivocally paves the way for deploying solar-driven catalytic systems in addressing environmental and energy crises through smart design and scalable engineering.

Subject of Research:
Photoreforming of solid waste using single-source precursor-derived co-catalyst films.

Article Title:
Photoreforming of solid waste on 1 m² scale using single-source precursor-derived co-catalyst films.

Article References:
Bin Mohamad Annuar, A., Liu, Y., Bhattacharjee, S. et al. Photoreforming of solid waste on 1 m² scale using single-source precursor-derived co-catalyst films. Nat Chem Eng 3, 351–362 (2026). https://doi.org/10.1038/s44286-026-00406-y

Image Credits:
AI Generated

DOI:
10.1038/s44286-026-00406-y

Keywords:
Photoreforming, solid waste conversion, co-catalyst films, solar energy, hydrogen production, photocatalysis, renewable energy, waste-to-fuel, sustainable chemistry, scalable catalysis

Google’s TV Streamer 4K is $25 off, its best price ever

24 June 2026 at 14:30
A white Google Streamer device next to a white remote on a white TV console next to a green plant.

The Google TV Streamer 4K is more than just a terrific streaming device. It can also act as a smart home hub, letting you control all major smart home devices directly from your TV. Thanks to Prime Day, it’s now on sale for $74.99 at Amazon for Prime members, matching its best price to date. The streamer usually retails for $99.99, making this a $25 discount. If you don’t subscribe to Prime, it’s just $5 more at Best Buy and direct from Google.

The Google TV Streamer 4K is a great fit for people already invested in Google’s ecosystem. The device lets you control your TV with your voice via Gemini, while the Google TV interface pulls recommendations from across your streaming services and even displays Rotten Tomatoes scores. Setup is also quick and straightforward, taking only about 10 minutes in our testing. One particularly nice touch is that Google asks which streaming services you subscribe to during setup and then downloads the relevant apps for you, so you don’t have to install them one by one.

Beyond streaming, the device doubles as a Matter-compatible smart home hub, making it easy to check your front door camera when the doorbell rings, turn off the lights, or adjust compatible thermostats and other smart devices without getting up. Google has also added a few extra conveniences, including a remote-finder function and an ethernet port for a more reliable connection.

Read our Google TV Streamer 4K review.
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The Dyson PencilWash is down to its lowest price ever for Prime Day

A Dyson PencilWash cordless hard floor cleaner cleaning a path across a wood floor and about to go over two small spills on an adjacent section of tile.

Dyson’s PencilWash cordless hard floor cleaner is on sale for $199.99 ($150 off) at Amazon. This is the lowest price yet for the powered wet mop that’s a cousin to the silly-sounding-but-awesome Dyson PencilVac Fluffycones vacuum.

The PencilWash basically takes the sleek styling and design of the PencilVac and simplifies it into a single-purpose electric mop. It’s designed for all manner of hard home flooring, and its slim head and pivoting neck allow it to get low to reach underneath furniture. Dyson claims you can get 30 minutes of cleaning time before you have to pop it onto the included charging dock, and the 300ml water tank is estimated to cover up to 1,000 square feet before needing a refill.

Dyson PencilWash

Where to Buy:

While the pencil name is cute, and the mop certainly looks svelte, keep in mind that it weighs around five pounds (heavier than the PencilVac) before adding any water or cleaning solution to its tank. But its self-propelling brush should help push that heft around your space without most of the weight being felt in your hand — until you’re mopping stairs.

$200 isn’t cheap for a single-purpose cleaning tool (let alone its full price of $350), but the PencilWash costs much less than the $600 PencilVac Fluffycones. Our own smart home reviewer, Jennifer Pattison Tuohy, called the PencilVac “the perfect companion to your robot vacuum.” The PencilWash is like the companion for that companion.

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