A biotech startup called Bexorg is doing something that sounds like it was ripped straight from the pages of a cyberpunk novel — or from the script of “RoboCop,” for that matter.

The company is extracting human brains just hours after their owners died and then hooking them up to specialized life support machines, Science reports. While the masses of pink mush no longer host electrical activity, most of their key functions remain intact, allowing scientists to test experimental drugs, such as potential treatments for Alzheimer’s disease, like never before.

You’d hope that the disembodied cerebrums are most assuredly dead. But according to the reporting, an extracted brain hooked up to one of Bexorg’s proprietary life support machines, BrainEX, “hovers between life and death.” There’s no spark of consciousness, and yet the brains are kept running on an artificial lung, kidney oxygenate, blood, and other fluids.

Perhaps you can put this ambiguity down to the startup being deliberately enigmatic to provoke attention. Or maybe it’s a reflection of how the distinction between life and death is uncomfortably blurry.

But you can put those doubts out of your very-much embodied mind, assures Brendan Parent, one of Bexorg’s six ethicists. The extracted brains are almost devoid of the coordinated neural firing necessary for minimal consciousness, he told Science. To prevent the eerie implausibility that some the brains produce electrical activity, the brains are also dosed with anesthetic propofol. Of course, that such a measure has to be taken in the first place may actually be less assuring and more unsettling.

Ethics aside — not a statement that should be made lightly — the scientific possibilities that these extracted brains afford may well hold promise. Bexorg CEO Zvonimir Vrselja said that the brains come with decades of environmental exposures, histories of drug treatments, and other factors that make them a more realistic testing medium for drugs. “You get cells that have been there for 60 to 80 years,” Vrselja told Science.

Bruna Bellaver, who studies neurodegeneration at the University of Pittsburgh, was also effusive. 

“It’s a huge step up from mouse models,” she told Science.

Bexorg is the same startup that demonstrated, over six years ago, that it could keep decapitated pig brains alive for 36 hours using a prototype of its BrainEX machine.

Today, its human brains aren’t kept running in perpetuity. After 24 hours, they’re sliced into hundreds of pieces so they can be analyzed by scientists. The company plans to use a robotic arm to slice up to 1,600 brains per year.

Though Bexorg hasn’t itself published any papers on its work with human brains, other companies have already been eagerly experimenting with them. The pharmaceutical firm Biohaven has used 130 of its brains to test drugs, according to Science, including a potential treatment for Parkinson’s disease, and plans to launch a clinical trial for another drug using data it gathered from those experiments.

More on neuroscience: Scientists Say Test Subjects Were Able to Quit Smoking After They Blasted Their Brains With a Huge Magnet

The post Startup Testing Drugs on Freshly Extracted Human Brains That Are Kept On Life Support appeared first on Futurism.

Therapy is predicated on trust. You can’t be honest and vulnerable, and share how you’re really feeling, if you don’t believe in the embodied-concerned-frown sitting in the armchair across from you.

So you can understand why one woman, 31-year-old Molly Quinn, was taken aback when her trusted therapist suddenly whipped out an AI model to start recording their private conversations, NPR reports. 

“She wasn’t taking notes like she usually did,” Quinn recalled realizing halfway through one session. “The iPad was just propped up.”

Where were her words being processed and stored? Will they one day become training data? It’s not something you have to ask yourself when your therapist jots stuff down on a clipboard. But those questions were now racing through Quinn’s head, leaving her uneasy.

“The more I thought about it, the more I just started getting more and more sick to my stomach,” she told NPR. “This person who I’m supposed to be able to trust with some very private and very intense emotions had just completely disregarded something I said I was not comfortable with. I felt completely violated.”

Though her therapist offered to stop using the AI tool, Quinn cut her off and found another one.

“The trust was gone,” she told NPR.

Like doctors, therapists across the country are adopting AI tools for notetaking and generating transcripts. AI companies offering these services frame it as a way of cutting down on the drudgery of paperwork and other administrative tasks, freeing up more time to focus on patients — a permutation of a common AI industry refrain: let us do the tedious stuff for you. 

The reliability of AI tools remains fairly dodgy, though, and even setting aside questions of hallucinations creeping into clinical notes — which is something we’re already seeing happen — it’s not clear whether patients are even comfortable with the tech yet. In a YouGov survey cited by NPR, only 11 percent of Americans said they would be open to using AI in mental health care. An even slimmer eight percent said they would trust AI being used this way, while 40 percent said they don’t trust the technology at all.

“Even the presence of AI changes the therapeutic experience,” Marisa Cohen, a couples and sex therapist in New York, told NPR. “Clients know or feel like something else is listening to them. That awareness can subtly alter their disclosure.”

“When you introduce something that’s being stored electronically, it raises additional questions about trust and safety,” Cohen added. “It’s essentially a third party.”

Tal Salman, the CEO a popular AI scribe tool for therapists called Berries, insists that conversation recordings are deleted immediately and that transcripts are stored on HIPAA compliant servers in the US. Even if this is true, if AI companies’ tools are to ever have a place in private mental health settings, they need the trust of patients — and that’s something the AI industry clearly hasn’t earned yet. Quinn fears that AI-recorded conversations could one day be exposed by hackers.

“We’re going to see breaches,” she told NPR. “Maybe not tomorrow, maybe not next week. But in a few years? I think we’re going to see them. And I don’t want my therapy session to be part of that.”

More on AI: The Pope Just Low Key Declared Holy War on Artificial Intelligence

The post Woman Alarmed When Her Trusted Therapist Starts Recording Her With AI appeared first on Futurism.

Parents say their kids are going ballistic when they take their iPads away from them, leaving them unsure of what normal behavior might be — and whether there’s something sinister going on with their child’s connection to the devices.

Rachel, a mother of two, tried limiting her son Jonah’s screen time by warning him that he had put down his iPad to leave for a birthday party at 11 AM. Despite the repeated warnings the day before and several reminders before the hour mark, when it came time to leave, Jonah had a meltdown.

“He just left his body,” the mother told The Cut of her son, who hurled the electronics and started screaming: “You said I had until 11! It’s not 11 yet! You’re always doing this!”

Jonah followed her around the house, distraught, until finally collapsing on the kitchen floor and refusing to move.

“I remember standing there thinking, I don’t know this person,” she recalled. “I genuinely did not recognize him.”

Thirty minutes later, he tied his shoes, got in the car, and acted like nothing had happened.

“That’s the part that really messes with you,” Rachel says. “How fast they come back.”

Think that’s bad? Hear what Nora had told The Cut about her 13-year-old son when she asked to check his phone settings: he accused Nora of ruining his life, before dropping a grenade in conversation.

“You make me want to kill myself,” he lashed out.

And while getting dinner last month at an Italian restaurant, Rachel told the outlet that she allowed her daughter Maya to watch YouTube Kids on the phone. When it was time too leave, she took the phone back. Maya went rigid, screamed, and hid under the table.

What’s going on here? Are these the kind of extreme tantrums that kids are prone to throw no matter the toy they’re being deprived of? Is everyone a bad parent, or at least not handling this the right way? Or are apps and the devices they run on uniquely addictive, somehow impacting a child’s development in novel and frightening ways?

The research into this area is still emerging, as are the generation of children raised on YouTube Shorts, Roblox, and other mobile games. That’s to say that we’re still a long way from grasping the long-term cognitive effects of being a so-called “iPad kid.” And the latest Silicon Valley horror, AI chatbots, are an even bigger question mark.

What evidence we do have, however, is alarming. The Cut cites a recent University of Washington study that found that 22 percent of parents’ attempts to cut down screen time sparked a negative reaction from kids under five. And in another study from Brigham Young University, 93 percent of parents reported that their toddlers would sometimes whine or throw tantrums when “transitioning away from media.”

Experts are mixed on whether the devices are provoking some newly negative response. 

“We frequently hear from parents who say, ‘When I ask my child to get off technology, they get very mad at me.’ That is true of almost anything that children find reinforcing,” Dave Anderson, a senior psychologist at the Child Mind Institute in New York City, told The Cut.

Anderson was skeptical of using the word addiction to describe what’s fueling iPad rages, noting that withdrawal symptoms of actual addiction don’t disappear within minutes. Kid’s minds just aren’t developed enough to handle having their favorite toy taken away from them, she said.

Stanford psychiatrist Anna Lembke, however, hasn’t hesitated to invoke the specter of addiction, calling screen devices a “digital drug” in an interview with Oprah. And Sarah Coyne, a professor of human development at Brigham Young, seemed to consider equating post-iPad rages to tantrums related to other pleasures outrageous. 

“I’m not sure how many children are struggling to function because their parents tell them to be done with their ice cream,” she told The Cut, adding that she’s seen addiction-like behavior in kids using devices as young as two years old.

If describing these patterns as signs of outright addictive behavior goes too far, there’s certainly there is a lot of evidence painting screen time’s cognitive effects. One study found that the more  babies and toddlers looked at screens each day, the more likely they were to miss key development goals, including fine motor skills and social skills.

The effects are no less worrying in older children. A study that followed tweens over four years found that increased screen time was a reliable predictor of ADHD diagnoses. Beyond iPad rages and worrying cognitive trends, there are other behaviors that illustrate the impact of device usage on children. In a survey of UK preschool school teachers, the teachers on average estimated that a third of their pupils didn’t know how to correctly use books — as in they literally couldn’t figure out that they had to turn the page. Instead, some reportedly tried to swipe or tap them.

More on mental health: Influential Tech Founder Says His Peers Are Suffering From Mass AI Psychosis

The post Kids Are Flying Into Lunatic Rages When Their iPads Are Taken Away appeared first on Futurism.

It’s no secret that many of the world’s top CEOs are obsessed with AI. By pursuing lofty goals of complete AI automation, these executives have created one of the largest financial bubbles in recent memory while transforming the job market into a barren wasteland, with little to show for their efforts so far.

As the top tech companies have yet to find a way to turn AI into a profitable venture, those decisions to go all-in on AI are looking increasingly delusional. According to Aaron Levie, CEO and founder of the massive cloud computing company Box, there’s a simple explanation for it: many of his colleagues are suffering from AI psychosis.

“CEOs are uniquely prone to AI psychosis because they’re sufficiently distant from the last mile of work that still has to happen to generate most value with AI,” Levie wrote on X-formerly-Twitter. Translation: AI-happy CEOs are out of touch with the rank-and-file workers tasked with making their AI ambitions come to life.

As an example, Levie offers cases in which corporate executives say “look I made this awesome product prototype” with an AI chatbot. “Yes but you didn’t have to review the code before it went into production and fix a bunch of issues,” he retorts.

Whether “AI psychosis” is the best metaphor for this concept is up for debate. Arguably the most common definition of AI psychosis is that it’s a phenomenon where extreme interactions with AI triggers or amplifies delusions or paranoia, sometimes already existing and sometimes seemingly newly cooked up with the AI. The symptoms can be extreme, with AI chatbots convincing victims that they’re communing with God-like entities, or have singlehandedly uncovered a grave threat to humankind.

There are indeed some executives who seem to fit the bill. Last year, Futurism reported that colleagues of Geoff Lewis, managing partner of the multi-billion dollar investment firm Bedrock, were concerned that he was suffering from a break with reality after spending too much time with ChatGPT (ironically, Bedrock was an early investor in OpenAI.) In that case, Lewis had claimed to be mapping an incomprehensible “non-governmental system” that was designed to disrupt his life.

That said, there’s a major gap between an exec believing they’re targeted by a vast conspiratorial network and an exec buying into AI hype. The phenomenon Levie is identifying might better fall under “organizational blindness,” a known phenomenon where leaders of a company find themselves disconnected from the reality of work on the ground. Coupled with a ravenous hunger for profit, this kind of tunnel vision seems to be exactly what we’re seeing in companies around the globe.

In today’s world, many executives and managers operate at an abstract level, working via spreadsheets, emails and Zoom meetings. This is different from concrete labor, meaning the specific, friction-heavy tasks that workers perform, like writing code or wiring server racks. When a board-room full of executives loses sight of this tangible labor — by failing to consider the kinds of tasks AI chatbots are actually good at, for example — it can certainly create a break from material reality, though one driven by social factors rather than psychological.

In other words, there are two possibilities: either the world’s CEOs are losing their minds, or they’re just succumbing to the latest manifestation of capitalism run amok. Occam’s razor probably suggests the latter.

More on AI and CEOs: 99 Percent of CEOs Are Preparing to Lay Off Workers and Replace Them With AI Within Two Years, Survey Finds

The post Influential Tech Founder Says His Peers Are Suffering From Mass AI Psychosis appeared first on Futurism.

Longtime Cybertruck watchers might remember a peculiar day back before the brutalist pickup was even released, when Tesla CEO Elon Musk randomly tweeted that the vehicle would function as a rudimentary flotation device.

“It will even float for a while,” he wrote at the time.

It wasn’t a one-off claim. Musk later boasted that the vehicle would be able to “traverse at least 100m [330 feet] of water as a boat.”

“Mostly just need to upgrade cabin door seals,” he claimed, writing at another point that the “Cybertruck will be waterproof enough to serve briefly as a boat, so it can cross rivers, lakes and even seas that aren’t too choppy.”

The Cybertruck finally did make it to market, where it’s suffered a seemingly endless parade of recalls, embarrassing incidents, and dismal sales figures.

Unsurprisingly, all Musk’s bluster about the truck serving as a makeshift schooner turned out to be flimflam. In fact, it quickly emerged that just getting wet in a car wash could brick the thing.

To muddy the waters further, the company ended up adding what it calls “Wade Mode” to the vehicles, which sets the truck’s ride height to the highest level, ostensibly so it can ford creeks and streams.

All that mixed messaging clearly got jumbled for a Texas man, though, who activated Wade Mode and drove his Cybertruck into a lake. Unsurprisingly, things didn’t go well for him.

“Yesterday, [Grapevine Police Department] and [Grapevine Fire Department] were dispatched to Grapevine Lake, where a Tesla Cybertruck was stranded in the water,” police in Grapevine, Texas, wrote on X-formerly-Twitter. “The driver drove into the lake to use the ‘Wade Mode’ feature when the vehicle became disabled.”

Not only is the man’s vehicle swamped — as the cops showed in an amazing attached photo — but he’s in legal trouble as well.

“The passengers abandoned the vehicle and the driver was arrested,” they wrote.

More on the Cybertruck: Cybertruck Recalled to Keep Its Wheels From Flying Off While Driving

The post Man Drives Cybertruck Into Lake to Test Elon Musk’s “Boat” Claims, and It Went About as Well as You’d Guess appeared first on Futurism.

Some effects can be traced to chemical signals inside appetite neurons.

Japanese researchers may have found a way to help neurons.

By tracking eye movements in zebrafish, researchers identified four different types of sleep, analogous to the complex sleep patterns of humans and other animals.

New research from the University of Oxford and the University of Reading suggests bipedalism and expanding brain size helped drive the overwhelming dominance of right-handedness in humans.

The post Upright Walking and Larger Brains May Explain Why 90% of Humans Favor Their Right Hand appeared first on Sci.News: Breaking Science News.

Engaging the fine motor system to produce letters by hand has positive effects on learning and memory

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A long-awaited study of people with ME/CFS revealed differences in their immune and nervous system. The findings may offer clues about long COVID

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Virtual-reality could assist researchers in decoding how emotions spur a decision to commit a crime

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