A new AI framework called MouseMapper allows scientists to examine disease-related changes across the entire body at cellular resolution. Obesity does much more than affect metabolism and fat storage. It also changes immune activity, nerve structure, and tissue organization throughout the body, raising the risk of conditions such as type 2 diabetes, cardiovascular disease, stroke, [...]

Scientists identified phosphatidylcholine loss as a key driver of mitochondrial aging and showed that restoring it can rejuvenate cellular energy networks. Why do cells age, and why do people gradually lose energy and vitality over time? Scientists have long focused on mitochondria, the tiny structures inside cells responsible for producing energy. Researchers now understand that [...]

Stanford researchers have developed a microscope that can show how nanostructures interact inside living cells at the highest resolution achieved so far. The view into living cells just got better. Stanford researchers have merged two microscopy methods to build a unique instrument that can capture cell structures interacting in real time at an unprecedented resolution [...]

A new evolutionary analysis suggests that modern blood and immune cells may preserve a 700-million-year legacy inherited from ancient single-celled ancestors. Long before humans, dinosaurs, or even fish existed, ancient single-celled organisms may have already carried the genetic blueprint for one of the body’s most important systems: blood. A new study from Kyoto University suggests [...]

Scientists are discovering that some of the cells linked to aging may also be key to staying healthy. A growing body of research is changing how scientists view one of aging biology’s most studied cell types: senescent cells, often called “zombie cells.” While these cells have long been associated with aging and chronic disease, new [...]

A remarkable new study of the world’s oldest verified living person reveals a surprising picture of extreme longevity. Maria Branyas lived through two world wars, the 1918 flu pandemic, the Spanish Civil War, and COVID-19. When she died in 2024 at age 117 years and 168 days, she was the oldest verified living person in [...]