The estimated size of the Ebola outbreak in the Democratic Republic of the Congo has fallen by hundreds of cases as outbreak response efforts have ramped up and increased testing has ruled out illnesses.

On Tuesday, a representative for the World Health Organization confirmed to Reuters that Congolese authorities are now reporting 437 cases in the DRC, including 321 confirmed cases and 116 suspected. That's a significant difference from the case count the WHO relayed Friday, which totaled 1,041 cases, including 135 confirmed cases and 906 suspected. Over the weekend, the director-general of the Africa Centres for Disease Control and Prevention, Jean Kaseya, also wrote in an op-ed that there were more than 1,100 suspected cases.

The number of deaths has also been lowered to 48 confirmed deaths. On Friday, the WHO had reported 241 deaths, including 18 confirmed and 223 suspected.

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The global health organization Coalition for Epidemic Preparedness Innovations (CEPI) announced Monday that it will "urgently accelerate development" of three vaccine candidates against Bundibugyo ebolavirus (BDBV), pledging a little over $60 million in the effort to extinguish an outbreak currently raging out of control in the Democratic Republic of the Congo.

Under the plans, CEPI has committed up to $50 million to US-based Moderna for preclinical development and Phase 1 clinical testing of its mRNA-based BDBV vaccine candidate. The funding will simultaneously allow the company to ramp up manufacturing capabilities and ready large-scale Phase 2/3 trials in the event the vaccine makes it through early testing. The vaccine will use Moderna's mRNA vaccine platform that allowed for rapid development of a COVID-19 vaccine during the pandemic.

"[W]e believe our mRNA platform can play an important role in responding rapidly to emerging infectious disease threats," Moderna CEO Stéphane Bancel said in a statement Monday. " We will move with urgency and scientific rigor to support the response and help bring a potential vaccine closer to the communities that need it most."

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The American Medical Association came out swinging this weekend at an executive order President Trump signed Friday that reaffirms intentions to model US childhood vaccine recommendations after those of Denmark—a country with universal healthcare, less diversity, and a population about the size of Maryland's.

“There is no credible scientific evidence to support," such a change, AMA President Bobby Mukkamala said in a statement. The current vaccine schedule "is built on decades of rigorous research and real-world data, and it is designed to protect children in the US when they are most vulnerable based on our nation’s disease burden," he said.

The plan to align federal childhood vaccine recommendations with Denmark's was first revealed by anti-vaccine Health Secretary Robert F. Kennedy Jr. in January. The overhaul would see the total number of recommended immunizations drop from 17 to 11, walking back recommendations for shots against rotavirus, COVID-19, influenza, meningococcal disease, hepatitis A, and hepatitis B. It stemmed from a December executive order by Trump to align US vaccine recommendations with the "best practices from peer, developed countries."

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The Trump administration is refusing to repatriate Americans exposed to Ebola amid the outbreak still raging in the Democratic Republic of the Congo. But the plan to send US citizens to Kenya has hit a snag, and officials are still scrambling to find other countries that might take them.

Earlier this week, it was revealed that the administration had devised a plan to establish a makeshift quarantine and treatment facility in Kenya—instead of bringing its citizens home for high-quality care at specialized facilities built for this purpose. According to the initial plans, the US facility would be in Laikipia, about 120 miles north of Nairobi, where the US has an air base. Initially, the plan was to set up a 50-bed quarantine facility that was expected to be operational today, May 29. Then, in a second state, officials would set up isolation and biocontainment units to house Americans infected with the virus.

But after a series of events on Thursday and Friday, that plan has now been stalled. The Katiba Institute, which advocates for Kenyans' constitutional rights, filed the petition on Thursday to challenge the establishment of the quarantine and treatment facility.

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For years, anti-vaccine Health Secretary Robert F. Kennedy Jr. and his zealous followers have downplayed measles as "just a rash" and falsely claimed that "Measles outbreaks have been fabricated to create fear."

In 2021, when Kennedy wrote those words, the US recorded just 49 measles cases. Yearly case counts have generally been low since 2000, when the US declared measles eliminated thanks to a decades-long vaccination campaign. But with the rise of Kennedy and his ilk in the past few decades, that public health triumph is being undone. Vaccination rates have slipped, and large, multistate outbreaks of vaccine-preventable diseases have inevitably come roaring back. Now it's becoming painfully clear once again how wrong Kennedy and his cohorts are about infectious diseases and vaccines.

In a study published yesterday in the Morbidity and Mortality Weekly Report, state and federal researchers provided a detailed postmortem of last year's massive multi-state measles outbreak that mushroomed out of West Texas. The data reveals a disease that's far from just a rash, with about 20 percent of people—mostly younger children—being hospitalized.

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