Semaglutide is best known as the active ingredient in the diabetes drug Ozempic and the weight-loss drug Wegovy. It belongs to a group of medicines called GLP-1 drugs, which can reduce appetite, improve blood sugar control and help people lose weight. New animal research suggests the drug may also affect some of the biological changes […]

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Most weight lost with GLP-1 obesity drugs came from fat, while relative muscle mass was largely preserved. GLP-1 obesity drugs can lead to substantial weight loss, but an important question is what the body is actually losing. New research presented at the European Congress on Obesity (ECO2026) suggests that 80-85% of weight lost during treatment [...]

Losing weight is one challenge, but keeping it off while maintaining a healthy diet can be even harder. New research suggests that a Mediterranean-inspired eating plan redesigned for the American South can help adults maintain weight loss for two years while improving the nutritional quality of their diets. The program is called Med-South and was […]

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In a two-year head-to-head trial, researchers found that two very different dietary approaches produced similar changes in body weight. A Mediterranean-style eating plan adapted to Southern food preferences helped participants lose about as much weight as WeightWatchers over two years, but it produced substantially greater improvements in reported diet quality. The comparison was part of [...]

Muscles need fuel to work, and they can use both sugar and fat for energy. But when too much fat becomes trapped inside muscle cells, this normal energy system can begin to work less efficiently. Excess fat inside skeletal muscle is sometimes called myosteatosis. It is associated with aging, inactivity, obesity and high-fat diets, and […]

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Many weight-loss plans ask people to count calories, measure portions, or deliberately eat less. A new clinical study suggests there may be another approach: changing the kinds of foods on the plate so that people can eat satisfying amounts while naturally taking in fewer calories. The research found that adults with overweight who followed a […]

The post Why a Low-Fat Vegan Diet May Help People Lose Weight Without Eating Smaller Meals appeared first on Knowridge Science Report.

Medicines such as GLP-1 receptor agonists can help people with type 2 diabetes lose substantial amounts of weight, but doctors have questioned what that weight loss might mean for aging bones. A large UCLA Health study now offers some reassuring evidence. Instead of seeing more serious fractures, researchers found fewer among patients who started GLP-1 […]

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An oral GLP-1 drug showed promising weight loss results in a phase II trial. A pill-based approach to GLP-1 treatment helped adults with obesity or overweight lose as much as 12 percent of their body weight over 36 weeks, according to a randomized phase II clinical trial published in Nature Medicine. The study tested aleniglipron, [...]

Biological defenses make losing weight and keeping it off unusually difficult. Better treatments, healthier environments, and sustainable habits may support long-term health more effectively than willpower alone. For years, weight loss has been framed as a simple test of discipline: consume fewer calories and exercise more. Modern research, however, shows that body weight is regulated [...]

Medicines called GLP-1 receptor agonists have become some of the most talked-about drugs in recent years. They were first developed to help people with type 2 diabetes manage their blood sugar levels. Later, doctors discovered that these medicines could also help people lose weight by reducing appetite and making them feel full for longer. As […]

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Obesity and type 2 diabetes affect hundreds of millions of people around the world. These conditions are known for causing problems with blood sugar and body weight, but their effects reach far beyond that. People with obesity and type 2 diabetes also have a much higher risk of developing heart disease, strokes, and other serious […]

The post These drugs Can Protect Blood Vessels in Obesity and Type 2 Diabetes appeared first on Knowridge Science Report.

Semaglutide was linked to greater weight loss and a 15% lower fracture risk in people with type 2 diabetes, raising the possibility of an unexpected bone health benefit. People with type 2 diabetes who took semaglutide experienced greater weight loss and a lower risk of bone fractures than those using several other weight-loss medications, according [...]

Medicines that help people lose weight have transformed the treatment of obesity in just a few years. Many people who struggled with weight for decades are now losing amounts of weight that were previously difficult to achieve without surgery. Among the most widely used treatments are a group of medicines called GLP-1 drugs. These medicines […]

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People taking popular GLP-1 weight-loss drugs like Ozempic, Wegovy, Mounjaro, and Zepbound may be shedding pounds, but a new study suggests they are also moving less. People with obesity who lost weight while taking popular medications such as Ozempic, Wegovy, Zepbound, and similar drugs became significantly less physically active, according to research presented at ENDO [...]

Weight-loss medicines such as semaglutide and tirzepatide have become some of the most talked-about drugs in the world. Their brand names, including Ozempic, Wegovy, Rybelsus, Mounjaro, and Zepbound, are now familiar to millions of people. They are often described as breakthrough treatments because many patients have achieved weight loss that was previously difficult to reach […]

The post Why Some People Lose a Lot of Weight on Ozempic and Mounjaro While Others Hardly Lose Any appeared first on Knowridge Science Report.

Semaglutide delivered dramatic weight loss and health benefits in adults over 65, offering new hope for healthier aging. A new analysis of data from the STEP clinical trial program suggests that semaglutide remains both effective and generally safe for older adults living with obesity. The research, conducted by Prof. Luca Busetto of the University of [...]

Obesity has become one of the biggest health challenges of modern times. Around the world, rising body weight is linked to higher risks of type 2 diabetes, heart disease, sleep problems, certain cancers, and many other medical conditions. For years, people trying to lose weight often struggled because lifestyle changes alone do not always produce […]

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For many people trying to lose weight, one of the biggest frustrations is seeing the weight return after months or years of hard work. Many people assume that once the weight comes back, all of the health benefits disappear as well. However, a new long-term study suggests that this may not always be true. Researchers […]

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For many years, doctors have encouraged people with obesity to lose weight in order to improve their heart health. Even modest weight loss can reduce strain on the heart, improve blood sugar levels, and lower blood pressure. Now, a major new study suggests that the latest generation of weight-loss medications may deliver significant blood pressure […]

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For years, most modern weight-loss medicines have worked by helping people feel less hungry. By reducing appetite, these drugs can lead to substantial weight loss and better blood sugar control. However, scientists are now testing a completely different strategy that may help people burn more energy without changing how much they want to eat. Researchers […]

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