NASA has selected 12 new investigations to help support human explorers in space. Six will help advance the ability to produce food off-planet, while another six advance the understanding of how unique conditions associated with space exploration can impact the health and physiology of astronauts.  

The six food-focused investigations, supported by the agency’s Space Crops grants, advance NASA’s goal of harnessing the power of plants to enhance quality of life for humans in space, as well as to enable lunar and Mars exploration. Four of the space crops proposals focus on studies of edible plants and how their growth, physiology, and associated microbial communities are affected by environmental conditions in space or on other planetary bodies.

Another proposal involves understanding mechanisms by which certain plant species, called resurrection plants, can withstand extreme, dry conditions. The last space crops proposal builds on previous studies on the International Space Station to uncover functions of algal genes, segments of DNA controlling algae survival, whose expression is modified by spaceflight. Such studies can help scientists integrate biological-based solutions into space life-support systems.

The second set of six proposals fall under the agency’s Biological and Physical Sciences Division’s focus on precision health, which seeks to unravel the mechanisms by which space exploration affects health and well-being. One proposal studies how lunar dust exposure impacts respiratory, immune, and inflammation responses.  A second proposal identifies repurposed drugs that can mitigate the effects space travel has on health and physiology.

Two more of the research proposals look at how radiation combined with other stressors affects age-relevant characteristics seen in various organ and physiological systems. The final two proposals assess molecular and cellular changes induced by stressors in space that can alter gene expression or protein function. The research will identify ways to mitigate health issues and develop early-warning detection systems to notify crew of potential concerns.

The principal investigators who conduct the space biology studies come from 10 institutions across eight states. Nine of the awards are for investigators who are receiving funding from the Space Biology Program for the first time.

Selected Space Crops Investigations

• Jannell Bazurto, University of Minnesota
  Cultivating the Cosmos: Investigating Plant-Microbe Dynamics for Sustainable Space Farming
• Miranda Haus, Michigan State University
  Investigating Legume Crop Rotations and Microbial Interactions in Regolith Simulants
• Andrew Settles, NASA Ames Research Center
  Genetic Mitigation of Spaceflight Stressors on Production of Chlamydomonas
• Christopher Taylor, Ohio State University
  Hydroponic Microbes in a Low Carbon, High-Radiation Environment; Identifying the Genetic Determinants of Water- and Plant-Associated Microbial Survival in Extraterrestrial Environments
• Robert VanBuren, Michigan State University
  Leveraging the Natural Resilience of Resurrection Plants for Space Bioregenerative Systems
• Shuyang Zhen, Texas A&M AgriLife Research
  Environmental Optimization and Cultivar Selection to Enhance Dwarf Tomato Growth and Stress Tolerance for Space Agriculture

Selected Precision Health Investigations

• Archana Dhasarathy, University of North Dakota
  Epigenetic Memory as an Adaptive Mechanism to Microgravity and Radiation Exposure
• Andrij Holian, University of Montana
  Contribution of Aging to Particle-Induced Chronic Inflammation
• Mert Gur, University of Pittsburgh
  Probing Pathogenic Mutations Under Spaceflight-Relevant Stressors Via All-Atom Molecular Dynamics Simulations
• Grace O’Connell, University of California
  Persistent Spine Health Impacts of Microgravity and Radiation Following Recovery
• Satoshi Okawa, University of Pittsburgh
  Investigating Space Flight-Induced Brain-Heart Axis Aging and Identifying Repurposed Drugs to Mitigate Its Effects
• Sanghee Yun, Ph.D., The Children’s Hospital of Philadelphia
  Spaceflight-Relevant Hypercapnia Effects on Space Radiation- and Social Isolation-Induced Biological Aging: A Systems Biology Analysis of Multiple Aging Hallmarks

When fully implemented, more than $7 million in grant money will be awarded throughout fiscal years 2026-2030. These awards were made in response to research proposals submitted to ROSES-2024: Program Element E.9: Space Biology Research Studies (NNH24ZDA001N-SBR).

To learn more about NASA’s biological and physical research in space, visit: https://science.nasa.gov/biological-physical/

Astronauts aboard the International Space Station have switched on NASA’s newly upgraded Cold Atom Lab, a one-of-a-kind facility designed to improve how scientists explore the fundamental workings of matter and develop new quantum technologies. By leveraging the unique environment of microgravity in space, the lab can accomplish cutting-edge science impossible to do anywhere else.

Quantum science is the study of matter at the smallest scales, like atoms, electrons, and single particles of light. While it’s easy to imagine atoms as billiard balls bouncing off one another, they also exhibit wave-like behavior, can exist simultaneously in two places at once, and may even pass through one another.

About the size of a minifridge and operated from Earth, the Cold Atom Lab chills atoms to temperatures below minus 459 degrees Fahrenheit (minus 237 degrees Celsius). At this extreme cold, just above absolute zero, atoms form a large quantum object called a Bose‑Einstein condensate, or BEC, a collection of matter waves that is a fifth state of matter beyond solids, liquids, gases, and plasma. This object follows the rules of quantum mechanics despite being much larger than subatomic particles, and the microgravity of low Earth orbit helps make the waves even larger.

“At the coldest temperatures, matter behaves drastically different from anything we have experienced,” said Jason Williams, project scientist for Cold Atom Lab at NASA’s Jet Propulsion Laboratory in Southern California, which built the facility. “The wavelike nature of matter dominates, and ultracold matter can behave in ways that are not only unexpected, but that also enable extremely precise measurements of time, gravity, and motion. The lab has lots of tools — especially with this latest upgrade — to let us probe the nature of the universe.”

The project supports five international teams studying fundamental physics. It also tests the space-readiness of quantum tools that could support future Earth science and space exploration missions.

How it works

The heart of the Cold Atom Lab is a complex set of instruments called its science module. An upgraded module launched on April 11 as part of a Commercial Resupply Services mission to the space station, enabling new kinds of experiments.

For each experiment, a strip of rubidium or potassium metal is heated to as high as 750 F (400 C) — hot enough to form a gas within the facility’s vacuum chamber. Lasers tuned to specific frequencies are then fired at the gas, draining the energy from these atoms, and cooling them by slowing them down. Once this gas has completed the laser-cooling stage, a magnetic trap captures and holds the gas in place. Through a series of complex techniques, the laboratory reduces an atom cloud’s energy further, bringing it close to a standstill and maximizing its time in microgravity.

While facilities for studying ultracold gases exist on Earth, the Cold Atom Lab can study quantum gases in microgravity for longer periods of time and at even lower temperatures. Conducting these experiments in low gravity allows scientists to study larger quantum waves that also interact for longer times with gravity. To harness these benefits, the Cold Atom Lab essentially shrinks an atom physics lab, typically the size of an entire room filled with lasers and tabletop mirrors, to fit within an experiment rack aboard the space station.

“As the first project to create Bose-Einstein condensates in orbit, we’re demonstrating that we can make quantum technology work reliably in space,” said Ethan Elliott, deputy project scientist for Cold Atom Lab at JPL. “In the previous century, there was a quantum revolution that led to lasers, cellphones, and MRIs for medical imaging. We’re performing quantum 2.0 — direct manipulation of large quantum states — and we hope for similar gains in quantum tech by advancing this science in orbit.”

The latest upgrade is the fourth since the Cold Atom Lab arrived at the space station in 2018. Key improvements include a newly designed magnetic trap that changes the shape of the quantum gas clouds, allowing scientists to test different properties related to their atoms. The upgrade also features redesigned metal strips that act as sources for those gas clouds.

“It’s the closest thing we have to controlling the boundary of the quantum world,” said Kamal Oudrhiri, project manager of Cold Atom Lab at JPL, referring to those low temperatures. “This new upgrade pushes that boundary even further.”

The upgrade, Oudrhiri added, “demonstrates NASA’s ability to maintain U.S. leadership in space-based quantum technologies while maturing future quantum instruments, such as matter-wave interferometers for fundamental physics missions, positioning, navigation, timing, and gravity sensing of Earth, the Moon, and beyond.”

More about Cold Atom Lab

Managed by Caltech in Pasadena, JPL designed, built, and operates the Cold Atom Lab, which is sponsored by the Biological and Physical Sciences division of NASA’s Science Mission Directorate at the agency’s headquarters in Washington. The division pioneers scientific discovery and enables exploration by using space environments to conduct investigations that are not possible on Earth. Studying biological and physical phenomena under extreme conditions allows researchers to advance the fundamental scientific knowledge required to go farther and stay longer in space, while also benefiting life on Earth. 

To learn more about Cold Atom Lab, visit:

https://nasa.gov/cold-atom-laboratory/

Media Contact

Andrew Good
Jet Propulsion Laboratory, Pasadena, Calif.
818-393-2433
andrew.c.good@jpl.nasa.gov

2026-039

The post NASA’s Quantum Lab Aboard Space Station Gets Chilly Upgrade appeared first on NASA Science.

Astronauts aboard the International Space Station have switched on NASA’s newly upgraded Cold Atom Lab, a one-of-a-kind facility designed to improve how scientists explore the fundamental workings of matter and develop new quantum technologies. By leveraging the unique environment of microgravity in space, the lab can accomplish cutting-edge science impossible to do anywhere else.

Quantum science is the study of matter at the smallest scales, like atoms, electrons, and single particles of light. While it’s easy to imagine atoms as billiard balls bouncing off one another, they also exhibit wave-like behavior, can exist simultaneously in two places at once, and may even pass through one another.

About the size of a minifridge and operated from Earth, the Cold Atom Lab chills atoms to temperatures below minus 459 degrees Fahrenheit (minus 237 degrees Celsius). At this extreme cold, just above absolute zero, atoms form a large quantum object called a Bose‑Einstein condensate, or BEC, a collection of matter waves that is a fifth state of matter beyond solids, liquids, gases, and plasma. This object follows the rules of quantum mechanics despite being much larger than subatomic particles, and the microgravity of low Earth orbit helps make the waves even larger.

“At the coldest temperatures, matter behaves drastically different from anything we have experienced,” said Jason Williams, project scientist for Cold Atom Lab at NASA’s Jet Propulsion Laboratory in Southern California, which built the facility. “The wavelike nature of matter dominates, and ultracold matter can behave in ways that are not only unexpected, but that also enable extremely precise measurements of time, gravity, and motion. The lab has lots of tools — especially with this latest upgrade — to let us probe the nature of the universe.”

The project supports five international teams studying fundamental physics. It also tests the space-readiness of quantum tools that could support future Earth science and space exploration missions.

How it works

The heart of the Cold Atom Lab is a complex set of instruments called its science module. An upgraded module launched on April 11 as part of a Commercial Resupply Services mission to the space station, enabling new kinds of experiments.

For each experiment, a strip of rubidium or potassium metal is heated to as high as 750 F (400 C) — hot enough to form a gas within the facility’s vacuum chamber. Lasers tuned to specific frequencies are then fired at the gas, draining the energy from these atoms, and cooling them by slowing them down. Once this gas has completed the laser-cooling stage, a magnetic trap captures and holds the gas in place. Through a series of complex techniques, the laboratory reduces an atom cloud’s energy further, bringing it close to a standstill and maximizing its time in microgravity.

While facilities for studying ultracold gases exist on Earth, the Cold Atom Lab can study quantum gases in microgravity for longer periods of time and at even lower temperatures. Conducting these experiments in low gravity allows scientists to study larger quantum waves that also interact for longer times with gravity. To harness these benefits, the Cold Atom Lab essentially shrinks an atom physics lab, typically the size of an entire room filled with lasers and tabletop mirrors, to fit within an experiment rack aboard the space station.

“As the first project to create Bose-Einstein condensates in orbit, we’re demonstrating that we can make quantum technology work reliably in space,” said Ethan Elliott, deputy project scientist for Cold Atom Lab at JPL. “In the previous century, there was a quantum revolution that led to lasers, cellphones, and MRIs for medical imaging. We’re performing quantum 2.0 — direct manipulation of large quantum states — and we hope for similar gains in quantum tech by advancing this science in orbit.”

The latest upgrade is the fourth since the Cold Atom Lab arrived at the space station in 2018. Key improvements include a newly designed magnetic trap that changes the shape of the quantum gas clouds, allowing scientists to test different properties related to their atoms. The upgrade also features redesigned metal strips that act as sources for those gas clouds.

“It’s the closest thing we have to controlling the boundary of the quantum world,” said Kamal Oudrhiri, project manager of Cold Atom Lab at JPL, referring to those low temperatures. “This new upgrade pushes that boundary even further.”

The upgrade, Oudrhiri added, “demonstrates NASA’s ability to maintain U.S. leadership in space-based quantum technologies while maturing future quantum instruments, such as matter-wave interferometers for fundamental physics missions, positioning, navigation, timing, and gravity sensing of Earth, the Moon, and beyond.”

More about Cold Atom Lab

Managed by Caltech in Pasadena, JPL designed, built, and operates the Cold Atom Lab, which is sponsored by the Biological and Physical Sciences division of NASA’s Science Mission Directorate at the agency’s headquarters in Washington. The division pioneers scientific discovery and enables exploration by using space environments to conduct investigations that are not possible on Earth. Studying biological and physical phenomena under extreme conditions allows researchers to advance the fundamental scientific knowledge required to go farther and stay longer in space, while also benefiting life on Earth. 

To learn more about Cold Atom Lab, visit:

https://nasa.gov/cold-atom-laboratory/

Media Contact

Andrew Good
Jet Propulsion Laboratory, Pasadena, Calif.
818-393-2433
andrew.c.good@jpl.nasa.gov

2026-039

Research Opportunities in Space and Earth Sciences (ROSES)-2025 is an ongoing “omnibus” or “umbrella” solicitation meaning that it includes many individual program elements each with its own topics and due dates. Refer to Table 3 of ROSES-25 for a list of those program elements. The ROSES-25 “Summary of Solicitation” is the front matter that sets the default backstop rules for each of the program elements in ROSES-25.

ROSES-25 Amendment 59 makes several additions, changes, and clarifications to the ROSES-25 Summary of Solicitation to conform with Agency and administration priorities, see Sections I, I(g), II(a), II(b), III(b), III(d), V(b)ii, VI(c) & VIII(b). New text is in bold.

Important and substantial revisions to 2 CFR 200, the government-wide guidance for grants and cooperative agreements are proposed to take effect October 1, 2026, see https://www.federalregister.gov/documents/2026/05/29/2026-10817/regulation-for-federal-financial-assistance#h-8. Many types of currently allowable costs, such as but not limited to publications, research or events outside the United States, and domestic conferences may be restricted, denied, or may be allowable by legal exception or special award conditions only. Public comments on the revisions to 2 CFR 200 may be submitted until July 13, 2026, at https://www.regulations.gov/commenton/OMB-2026-0034-0001

On or about June 15, 2026, this Amendment to the NASA Research Announcement “Research Opportunities in Space and Earth Sciences (ROSES) 2025” (NNH25ZDA001N) will be posted on the NASA research opportunity homepage at https://solicitation.nasaprs.com/ROSES2025 and will appear on SARA’s ROSES blog at: https://science.nasa.gov/researchers/solicitations/roses-2025/

Questions concerning this amendment to ROSES-25 may be directed to SARA@nasa.gov.

The post Amendment 59: Several Updates to the ROSES-25 Summary of Solicitation appeared first on NASA Science.

Since NASA’s Artemis II crew members safely splashed down in the Pacific Ocean on April 10 after their record-setting mission around the Moon, science teams have been busy collecting more data and combing through observations collected on the test flight. Results from these science investigations will help support safe human exploration of deep space and provide a blueprint for how future missions will conduct science on the lunar surface as NASA builds a Moon Base and develops an enduring human presence there.

Postflight crew health, performance data

In the hours, days, and weeks after landing, the Artemis II crew members, NASA astronauts Reid Wiseman, Victor Glover, Christina Koch, and CSA (Canadian Space Agency) astronaut Jeremy Hansen, contributed critical data to help the agency understand how the human body reacts to spaceflight. Collecting this data as soon as possible after landing was important to understand how the body adapts from microgravity to Earth’s gravity. The data will inform NASA’s understanding of how quickly crews can complete mission-critical tasks after landing on a planetary surface like the Moon or Mars, where there won’t be landing support personnel to assist.  

Within a day of splashdown, researchers collected a suite of data for the Artemis II Spaceflight Standard Measures study, which is part of a larger effort across the astronaut corps to gather a baseline set of health measurements on blood pressure, heart rate, eye health, and motor control. Crew members also completed a mini obstacle course, which included lying down, standing up, unfurling a rope ladder, ladder climbing, and more, to assess how their bodies were adapting to Earth’s gravity.

Once the crew returned to NASA’s Johnson Space Center in Houston, researchers guided them through further medical check-ups and tests of motor control. Over the next several days, the crew completed obstacle courses wearing spacesuits offloaded to lunar gravity, which is roughly one-sixth the force of Earth’s gravity. Researchers are now analyzing this data to gain insight into how crews may perform as they adapt to the gravity of a planetary surface.

As part of the Immune Biomarkers study, researchers are comparing blood and saliva samples collected after the Artemis II splashdown with samples collected preflight and during the mission. Among other topics, the study investigates whether and how dormant viruses reawaken in astronauts’ bodies while in space.

Some crew members completed postflight cognition tests and a simulated manual spacecraft docking task to assess motor control for the ARCHeR (Artemis Research for Crew Health & Readiness) study. This, combined with data collected through a wrist-worn device while crew members were in space, is used to understand the effect of space hazards on well-being and performance.

Initial data collections for Artemis II health studies concluded 45 days after splashdown. However, medical teams will continually monitor astronaut health throughout the Artemis II crew members’ lifetimes.

Once this data is processed and anonymized, information will be available for scientists to study the effects of spaceflight via a request to NASA’s Life Sciences Data Archive. The results from this work could lead to new technologies and studies that help predict the adaptability of crews on future missions to the Moon and Mars.

Analyzing astronaut-derived organ chips flown around Moon

Organ chips from NASA’s AVATAR (A Virtual Astronaut Tissue Analog Response) investigation are being analyzed at chip developer Emulate’s laboratory in Boston. The organ chips included bone marrow cells from each Artemis II astronaut. They flew around the Moon with the astronauts, and now researchers are studying these organ chips to determine how deep space radiation and microgravity affect human health at the molecular level.

Scientists are comparing the chips flown aboard the spacecraft to ground controls and crew blood samples using advanced techniques, including single-cell RNA sequencing. The analysis will characterize how organ chips model individual responses to spaceflight, which is data that could allow NASA to send future astronauts’ AVATAR chips ahead on missions to develop personalized medical kits. The researchers plan to share early findings at scientific conferences while full analysis continues.

Lunar imagery, audio for data release

On April 6, the Artemis II crew members studied features on and around the Moon for nearly seven hours during Orion’s closest approach to the lunar surface. Their work was guided by a minute-by-minute observation plan developed by the Artemis II lunar science team.

Scientists are reviewing the data collected from the mission, which includes images, video, and audio files, to release a report of their initial data interpretations later this year. The report will cover observations of impact flashes, variations in color on the lunar surface, and the shape and texture of faults and ridges. The team also will publish a report on how Artemis II lunar science observations were planned, organized, and executed for the benefit of future Artemis missions.

NASA will publish more than 100 science-related audio recordings with transcripts, as well as approximately 11,500 Earth and Moon image and video files from the mission science campaign, with accompanying data. While many of these images already are public, these records will be available through NASA’s Planetary Data System, a public archive of data from all of NASA’s planetary missions. To get the data ready, the team is converting files into standard formats that anyone can easily open and add information to make the data searchable in NASA’s archive for generations to come.

For more information on NASA’s Artemis II science efforts, visit:

https://www.nasa.gov/humans-in-space/artemis-ii-science/

Karen Fox / Molly Wasser

Headquarters, Washington

240-285-5155 / 240-419-1732

karen.c.fox@nasa.gov / molly.l.wasser@nasa.gov

The post NASA’s Artemis II Moon Mission Research Continues on Earth appeared first on NASA Science.

Since NASA’s Artemis II crew members safely splashed down in the Pacific Ocean on April 10 after their record-setting mission around the Moon, science teams have been busy collecting more data and combing through observations collected on the test flight. Results from these science investigations will help support safe human exploration of deep space and provide a blueprint for how future missions will conduct science on the lunar surface as NASA builds a Moon Base and develops an enduring human presence there.

Postflight crew health, performance data

In the hours, days, and weeks after landing, the Artemis II crew members, NASA astronauts Reid Wiseman, Victor Glover, Christina Koch, and CSA (Canadian Space Agency) astronaut Jeremy Hansen, contributed critical data to help the agency understand how the human body reacts to spaceflight. Collecting this data as soon as possible after landing was important to understand how the body adapts from microgravity to Earth’s gravity. The data will inform NASA’s understanding of how quickly crews can complete mission-critical tasks after landing on a planetary surface like the Moon or Mars, where there won’t be landing support personnel to assist.  

Within a day of splashdown, researchers collected a suite of data for the Artemis II Spaceflight Standard Measures study, which is part of a larger effort across the astronaut corps to gather a baseline set of health measurements on blood pressure, heart rate, eye health, and motor control. Crew members also completed a mini obstacle course, which included lying down, standing up, unfurling a rope ladder, ladder climbing, and more, to assess how their bodies were adapting to Earth’s gravity.

Once the crew returned to NASA’s Johnson Space Center in Houston, researchers guided them through further medical check-ups and tests of motor control. Over the next several days, the crew completed obstacle courses wearing spacesuits offloaded to lunar gravity, which is roughly one-sixth the force of Earth’s gravity. Researchers are now analyzing this data to gain insight into how crews may perform as they adapt to the gravity of a planetary surface.

As part of the Immune Biomarkers study, researchers are comparing blood and saliva samples collected after the Artemis II splashdown with samples collected preflight and during the mission. Among other topics, the study investigates whether and how dormant viruses reawaken in astronauts’ bodies while in space.

Some crew members completed postflight cognition tests and a simulated manual spacecraft docking task to assess motor control for the ARCHeR (Artemis Research for Crew Health & Readiness) study. This, combined with data collected through a wrist-worn device while crew members were in space, is used to understand the effect of space hazards on well-being and performance.

Initial data collections for Artemis II health studies concluded 45 days after splashdown. However, medical teams will continually monitor astronaut health throughout the Artemis II crew members’ lifetimes.

Once this data is processed and anonymized, information will be available for scientists to study the effects of spaceflight via a request to NASA’s Life Sciences Data Archive. The results from this work could lead to new technologies and studies that help predict the adaptability of crews on future missions to the Moon and Mars.

Analyzing astronaut-derived organ chips flown around Moon

Organ chips from NASA’s AVATAR (A Virtual Astronaut Tissue Analog Response) investigation are being analyzed at chip developer Emulate’s laboratory in Boston. The organ chips included bone marrow cells from each Artemis II astronaut. They flew around the Moon with the astronauts, and now researchers are studying these organ chips to determine how deep space radiation and microgravity affect human health at the molecular level.

Scientists are comparing the chips flown aboard the spacecraft to ground controls and crew blood samples using advanced techniques, including single-cell RNA sequencing. The analysis will characterize how organ chips model individual responses to spaceflight, which is data that could allow NASA to send future astronauts’ AVATAR chips ahead on missions to develop personalized medical kits. The researchers plan to share early findings at scientific conferences while full analysis continues.

Lunar imagery, audio for data release

On April 6, the Artemis II crew members studied features on and around the Moon for nearly seven hours during Orion’s closest approach to the lunar surface. Their work was guided by a minute-by-minute observation plan developed by the Artemis II lunar science team.

Scientists are reviewing the data collected from the mission, which includes images, video, and audio files, to release a report of their initial data interpretations later this year. The report will cover observations of impact flashes, variations in color on the lunar surface, and the shape and texture of faults and ridges. The team also will publish a report on how Artemis II lunar science observations were planned, organized, and executed for the benefit of future Artemis missions.

NASA will publish more than 100 science-related audio recordings with transcripts, as well as approximately 11,500 Earth and Moon image and video files from the mission science campaign, with accompanying data. While many of these images already are public, these records will be available through NASA’s Planetary Data System, a public archive of data from all of NASA’s planetary missions. To get the data ready, the team is converting files into standard formats that anyone can easily open and add information to make the data searchable in NASA’s archive for generations to come.

For more information on NASA’s Artemis II science efforts, visit:

https://www.nasa.gov/humans-in-space/artemis-ii-science/

Karen Fox / Molly Wasser

Headquarters, Washington

240-285-5155 / 240-419-1732

karen.c.fox@nasa.gov / molly.l.wasser@nasa.gov