U.S. health officials have identified shredded iceberg lettuce served at Taco Bell as one source of contamination behind an outbreak of parasitic infections affecting over 1,000 people.
The outbreak has been caused by the protozoan parasite Cyclospora cayetanensis, which can enter the body when someone consumes food or water contaminated with the parasite. Since May 1, there have been 1,644 confirmed cases across Indiana, Kentucky, Ohio, West Virginia and Michigan, which is currently the hardest-hit state.
(Health officials are also investigating additional cases of Cyclospora infection in the U.S. that have yet to be linked to this specific lettuce-related outbreak. Those other potential cases remain under investigation and total over 5,100, per the Centers of Disease Control and Prevention (CDC).)
In the five-state outbreak, there have been 94 hospitalizations and no deaths to date.
Through an investigation, health officials found that all 1,644 of the sickened people with confirmed cases of Cyclospora reported eating Taco Bell in Indiana, Kentucky, Michigan, Ohio or West Virginia before becoming ill. Interviews with the affected individuals suggested that shredded lettuce might be a common source of exposure.
The Food and Drug Administration (FDA) then investigated the source of the lettuce, identifying a single supplier of iceberg lettuce from Mexico that was used by Taco Bell locations where the people ate before becoming ill. News reports have named California-based Taylor Farms as the supplier.
"FDA is working directly with the identified supplier to determine if potentially contaminated shredded iceberg lettuce remains on the market," an FDA notice states. "As part of this investigation, FDA and state partners have initiated collection of product samples for testing and analysis."
The investigation is ongoing, and additional sources of contamination or affected restaurants could possibly be identified later, the FDA noted. In the meantime, Taco Bell has said it will stop using lettuce from the implicated supplier.
"Taco Bell is working to stop use of all lettuce implicated by this investigation. Not all Taco Bell locations in these states received implicated product," the FDA statement says.
Currently, the CDC is warning consumers not to eat shredded iceberg lettuce served at Taco Bell locations in Indiana, Kentucky, Michigan, Ohio or West Virginia.
Case counts reported by individual states may differ from the FDA's and CDC's counts, because states may include both probable and confirmed cases. The FDA and CDC will update their totals once they can confirm additional cases reported to them.
Symptoms of Cyclospora infection typically emerge two to 14 days after a person consumes the parasite. These symptoms include watery diarrhea, fatigue, cramping, bloating, gas and loss of appetite, and without treatment, they can last between a few days to a month or more. The infection is treated with an antibiotic, which blocks the parasite's ability to multiply.
This article is for informational purposes only and is not meant to offer medical advice.
O EX30 é o Volvo mais pequeno e mais acessível da gama, e um dos SUV elétricos compactos mais interessantes do mercado. Testámos a versão P5 Plus, com bateria de 55 kWh, e ficámos rendidos ao bom ambiente a bordo, e com a eficiência superior à anunciada. Mas não conseguimos ignorar algumas decisões de design que dão que pensar numa marca com o histórico de segurança da Volvo.
On Aug. 12, I get to fulfil a lifelong ambition. I'll take a flight to Madrid and travel northwest to the city of Valladolid by rail, before striking out for Valoria la Buena — a charming town in central Spain with a population of less than 1,000.
There, I'll bear witness to one of the most spectacular naked eye shows that the solar system has to offer: a total solar eclipse. My first total solar eclipse.
Don't get me wrong. I've been obsessed with eclipses my entire life. I just haven't found myself in the right place at the right time to experience totality until now. 10-year-old me came pretty close during a deep partial eclipse in 1999, when I caught a fleeting glimpse of the moon's silhouette taking a bite out of the sun in the cloud-ridden skies over the United Kingdom.
Smash cut 20-something years later and I'm inexplicably the Skywatching Writer for Space.com, where one of the major perks of the job is being sent to report on eclipses. Things aligned quite nicely.
The DEB is a network of enthusiastic solar observers led by professional astronomers who use standardized telescopes and software to share inspiring eclipse imagery to the public, while also capturing valuable scientific data on the sun's disk and golden atmosphere.
It was Greenwald who scouted Valoria la Buena as a prime location to observe the eclipse. He's since been hard at work liaising with DEB initiative leadership to test software updates and troubleshoot other issues, while also travelling toMexico to help train student members of the team ahead of their expedition to Spain. Two more eclipse enthusiasts are due to join the group once it arrives in Madrid, making it a wonderfully international affair.
Less than a month out, things are pretty settled, and a kind of nervous anticipation has taken hold. Flights and trains are booked, and I have a pair of Celestron EclipSmart 10x42 binoculars and the EclipSmart 3-Piece Solar Eclipse Observing and Imaging Kit, courtesy of Celestron. Also hats and an ungodly amount of suntan lotion. I'm bald after all, so the sun is my greatest natural predator.
Of course, preparations can only get you so far. Once we get to Valoria la Buena on Aug. 10 there'll still be important work to do. The first order of business for Charles and his DEB team will be to stake out a location with a clear line of sight to the west for their equipment. Totality will occur with the sun less than 10 degrees above the horizon — roughly the width of your clenched fist held at arm's length — so line of sight will be everything.
We'll also be at the mercy of the weather. Clouds could easily arrive to hide the cosmic show from view — especially with the eclipse so low on the horizon. The DEB team also has to find a spot with good connectivity, which will allow them to broadcast near-live images of our parent star for the public to enjoy and scientists to pore over.
The sun's atmosphere shines out from behind the moon during a total lunar eclipse. (Image credit: Photo by Keegan Barber/NASA via Getty Images)
All being well, myself, the DEB team and over 15 million others in the path of totality will bear witness to a heartstopping display of orbital mechanics that crescendos with the fleeting artificial night of totality, as the moon blocks the last sliver of the sun from view. Space.com's Skywatching Editor Daisy Dobrijevic will also be on hand to report on the total solar eclipse as it unfolds in the skies over Greenland.
Editor's Note: Want to share your eclipse photography with Space.com's readers? Then please send your photos and comments, along with your name and location to spacephotos@space.com.
ARK augmented reality describes a form of spatial interaction in which artificial intelligence does more than place digital objects in the physical world. It uses knowledge from foundation models to understand unfamiliar scenes, generate useful information and adapt its response to the person, task and environment.
The concept comes from a 2023 research paper titled “ArK: Augmented Reality with Knowledge Interactive Emergent Ability.” Its authors proposed a system that transfers knowledge from large foundation models into new physical and virtual environments. Instead of training an AI agent separately for every room, object or activity, ArK uses existing knowledge memory to interpret what it sees and generate appropriate 2D or 3D content.
Traditional augmented reality places information over reality. ARK augmented reality tries to understand reality before deciding what should appear.
That distinction creates a compelling direction for Apple. Vision Pro already blends digital content with physical space. Apple Intelligence adds language, image understanding and personal context. Visual Intelligence lets users look at objects, text and scenes before asking for information. Siri AI adds a conversational layer. ARKit, RealityKit and visionOS provide the spatial foundation.
Apple now has many of the components required to build a knowledge layer over the physical world.
ARK Augmented Reality Goes Beyond Digital Overlays
Most familiar augmented reality experiences are relatively fixed. A furniture app places a digital sofa in a room. A navigation app displays arrows over a street. A museum app identifies an artwork. A repair app shows where a component belongs.
These experiences can be useful, but they usually depend on predefined content and rules. The system recognizes a known object or location, then presents prepared information.
ARK augmented reality proposes something more adaptive. A knowledge-enabled system could enter an unfamiliar environment, interpret what is present and generate assistance based on a broader understanding of objects, relationships and possible actions.
A user looking at a complicated electrical panel would not only see labels. The system could identify the panel type, explain the purpose of each section, compare the arrangement with standard configurations and warn the user not to touch dangerous components.
A student examining a machine could ask how it works and receive a spatial explanation attached to its real parts. A surgeon could review anatomical information positioned around a medical model. A technician could receive repair guidance even when the exact equipment had not been included in a previous training dataset.
The display becomes less like a floating screen and more like an informed interpretation of the environment.
Image Credit: Apple Inc.
Why Apple Is Positioned to Build It
Apple’s advantage would not come from inventing every part of ARK augmented reality. It would come from combining hardware, software, artificial intelligence and personal context into one controlled ecosystem.
Vision Pro already understands rooms, surfaces, hands, eyes and objects well enough to place digital content convincingly in physical space. Its cameras and sensors continuously map the environment while visionOS manages windows, volumes and immersive experiences.
Apple Intelligence provides another layer. Foundation models can interpret language, summarize information, generate content and connect requests with app actions. Visual Intelligence can identify text, images and real-world objects. Siri AI can act as the conversational interface.
The Apple ecosystem also provides personal context that a generic AR platform may not have. Calendar knows the user’s schedule. Maps understands location. Photos contains visual history. Notes and Mail hold project information. Health contains personal trends. Home understands rooms, accessories and automations.
An Apple-built knowledge layer could combine the environment in front of the user with the information already available across trusted devices and apps.
A person preparing for a meeting could look at a conference room and see the agenda, participant names and relevant documents arranged around the table. A traveler could look across a train station and receive directions connected to the correct platform, departure time and digital ticket. A homeowner could examine a room and see live information from temperature, air-quality and energy sensors.
The physical environment becomes the interface.
Vision Pro Is the Laboratory
Vision Pro is the obvious development platform for this idea because it already offers the cameras, displays, sensors and processing required for advanced spatial understanding. Its size and price limit broad adoption, but those same characteristics allow Apple and developers to test experiences that would be harder to build first on lightweight glasses.
ARK augmented reality on Vision Pro could become especially useful in enterprise environments. Apple already promotes the headset for employee training, product design, field service, collaboration and specialized visualization.
A worker could enter an unfamiliar facility and receive contextual instructions attached to real equipment. An engineer could inspect a physical prototype while design changes, performance data and maintenance history appear around it. A new employee could learn a workflow through spatial guidance generated from company manuals and operational knowledge.
The system would not need to display every available fact. It would need to understand which information fits the current task.
That is where AI knowledge becomes more valuable than a traditional AR overlay. Too much information can be as disruptive as too little. A strong system should filter, prioritize and explain rather than cover the room with floating labels.
The iPhone Could Bring ARK to More People
Vision Pro may be the development environment, but iPhone could provide the scale. The iPhone already combines cameras, LiDAR on Pro models, location, motion sensing, Visual Intelligence and Apple Intelligence.
An iPhone-based ARK experience would be less continuous because users would need to hold up the device. It could still deliver useful knowledge interaction without requiring a headset.
A user could point the camera at a plant and receive care guidance based on its species, visible condition, local weather and placement in the room. Someone assembling furniture could receive generated guidance positioned over the actual parts. A shopper could compare products by looking at them rather than manually searching for each model.
The difference from ordinary visual search would be interaction. The user could ask follow-up questions, change the goal and let the system update the visual guidance.
Future glasses could eventually make the experience persistent. The iPhone would help Apple develop the intelligence, privacy controls and app ecosystem before lightweight eyewear becomes ready.
A World That Explains Itself
The most ambitious version of ARK augmented reality is a world in which information is attached to objects, places and situations only when requested or needed.
A city could become understandable without searching through maps, review sites and separate transit apps. Buildings could reveal history. Streets could explain temporary closures. Restaurants could surface reservations, dietary options and accessibility details. Public transport could show the correct entrance and platform.
Inside a home, Apple’s knowledge layer could explain energy use, identify maintenance problems and guide repairs. In a classroom, physical models could become interactive lessons. In healthcare, patients could receive visual instructions for approved home procedures or medication devices.
The experience would depend on context rather than menus. The user looks, asks and receives information positioned where it belongs.
This is the transition from augmented reality as decoration to augmented reality as understanding.
Privacy Will Decide Whether It Works
A knowledge layer capable of understanding the physical world also creates serious privacy questions. The system may see homes, workplaces, documents, faces, screens and private conversations. The more context it receives, the more useful it becomes. The same access can also make it invasive.
Apple’s privacy architecture could become one of its strongest advantages. On-device processing would allow some scene understanding without sending continuous camera feeds to external servers. Private Cloud Compute could handle more complex requests while preserving stricter controls than an ordinary cloud AI service.
Apple would also need visible controls over what is analyzed, remembered and shared. A user should know when the system is interpreting the environment and whether information is temporary or retained. Workplaces and public spaces would need rules for recording, identification and sensitive data.
ARK augmented reality cannot become socially acceptable if people feel that nearby devices are constantly cataloging them.
The successful version would behave less like surveillance and more like intentional assistance. The user asks for understanding. The system processes only what is needed. The knowledge disappears when the task ends unless the user chooses to save it.
Image Credit: Apple Inc.
Developers Could Build Knowledge Worlds
Apple would not need to create every knowledge experience itself. visionOS, ARKit, RealityKit and App Intents could let developers connect specialized knowledge with physical environments.
A medical company could build guidance for approved equipment. A manufacturer could create spatial maintenance systems. A university could attach interactive explanations to laboratories and museums. A retailer could create product comparisons based on inventory and customer preferences.
Apple could provide the shared intelligence layer: scene understanding, object recognition, language interaction, privacy permissions and spatial presentation. Developers would provide the trusted domain knowledge.
This division would be essential. General AI can explain many things, but professional environments require verified information. A generated answer about a historical building has different consequences from an answer about industrial machinery or medical treatment.
Apple’s platform could distinguish between general knowledge and certified domain sources, allowing users to see where information comes from before acting.
From Spatial Computing to Contextual Computing
Apple describes Vision Pro as a spatial computer because digital content can occupy physical space. ARK augmented reality suggests the next progression: contextual computing.
A spatial computer knows where digital content is placed. A contextual computer understands why the content is useful in that location, what the user is trying to accomplish and which knowledge should appear.
That would connect several Apple strategies that currently look separate. Vision Pro supplies spatial awareness. Apple Intelligence supplies reasoning and generation. Siri AI supplies conversation. Visual Intelligence supplies real-world understanding. The ecosystem supplies personal context.
Together, they could create a system that does not wait for users to open the correct app and search through the correct menu. The environment itself becomes the starting point.
Apple’s opportunity is to make that interaction restrained rather than overwhelming. The company does not need to cover reality with digital noise. It can use design, privacy and contextual intelligence to make information appear only when it improves the moment.
ARK augmented reality offers a useful description of that future. Reality remains visible. Knowledge becomes interactive. The computer begins to understand the world in front of the user instead of asking the user to translate everything into a search box.
A new Bayesian system called ALADYNOULLI is designed to forecast how multiple diseases unfold over time from longitudinal electronic health record (EHR) histories. The work targets a central challenge in longitudinal modelling: evaluating prediction without “information leakage,” so that future diagnoses never influence training for past timepoints. By explicitly simulating real clinical follow-up, the researchers aim to make risk estimates more trustworthy for decision-making.
In the primary assessment, ALADYNOULLI produced dynamic 1-year forecasts at 10 fixed moments during follow-up, starting at enrollment and extending to years 1 through 9. At each timepoint, models were retrained using only data available up to that moment, then tested on 1-year outcomes. The key metric was the median area under the receiver operating characteristic curve (AUC) across these dynamic evaluations, summarizing how predictive accuracy changes as new diagnoses accumulate.
The study spans 28 diseases and reports robust discrimination for several clinically important endpoints. Performance was strong for atherosclerotic cardiovascular disease (ASCVD), breast cancer, atrial fibrillation, heart failure, and Parkinson’s disease, with AUC values of 0.879, 0.867, 0.801, 0.811, and 0.796, respectively. Importantly, the evaluation excluded people with prevalent disease at prediction time, aligning the comparisons with prospective risk.
ALADYNOULLI was also benchmarked against established clinical risk tools where feasible. At enrollment, static models trained only on baseline information were compared for both 1-year and 10-year horizons. While longer-term predictions naturally degraded, ALADYNOULLI retained meaningful power—for example, for ASCVD at 10 years—highlighting the advantage of learning from longitudinal EHR trajectories rather than relying solely on cross-sectional inputs.
Calibration analyses further supported reliability: predicted and observed event rates matched closely across millions of at-risk patient-time observations. The researchers report a mean squared error on calibration of 4.67 × 10⁻⁷, with mean predicted rates (5.55 × 10⁻⁴) closely tracking mean observed rates (5.45 × 10⁻⁴). This suggests not only ranking accuracy, but also quantitative risk realism.
To test whether results were driven by subtle temporal artifacts, the team ran sensitivity analyses that excluded events occurring shortly before prediction and varied washout windows. They also examined alternative horizons and a dynamic 10-year rolling interpolation strategy, which updates risk estimates as annual information becomes available. Together, these checks help confirm that temporal patterns are being learned in a causally aligned manner.
Overall, the findings position ALADYNOULLI as a clinically relevant framework for multi-disease risk forecasting, combining longitudinal EHR modelling with predictive discrimination and calibration. By rigorously preventing leakage and validating dynamic follow-up scenarios, the approach offers a pathway toward more actionable, time-aware risk prediction in real-world healthcare settings.
Subject of Research: Longitudinal EHR-based multi-disease risk prediction using Bayesian modelling and genetic/EHR integration Article Title: A Bayesian framework for longitudinal EHR and genetic discovery. Article References: Urbut, S.M., Ding, Y., Nakao, T. et al. A Bayesian framework for longitudinal EHR and genetic discovery. Nature (2026). https://doi.org/10.1038/s41586-026-10780-5 Image Credits: AI Generated DOI:https://doi.org/10.1038/s41586-026-10780-5 Keywords: longitudinal EHR, Bayesian framework, disease risk prediction, dynamic forecasting, temporal validation, calibration, AUC, ASCVD
A new study in Nature Communications reports that subducting slabs can become effectively “stalled” for long periods—not simply due to mantle temperature or plate motion, but because distinct rock assemblages within the downgoing plate alter how the slab interacts with the surrounding mantle. Using geophysical constraints combined with thermodynamic modeling, the researchers argue that slab dynamics depend on whether the slab interior is dominated by hydrated ultramafic lithologies or by comparatively dry basaltic components.
The central finding is that wet harzburgite—an olivine-rich, ultramafic rock—can sustain slab stagnation by promoting hydration-related weakening processes and controlling the timing and location of mineral transformation. In parallel, the team shows that dry basaltic slab assemblages can also contribute to stagnation, but through a different pathway: by limiting certain water-driven reactions while still maintaining a mechanically coherent, slow-moving interface at depth.
According to the authors, the fate of volatiles is the key variable. As the slab descends, pressure and temperature drive phase changes and dehydration reactions. These reactions can either increase or decrease the effective viscosity and friction along plate boundaries, shifting the balance between slab pull and mantle resistance. Where hydration is sustained, water remains available to weaken lithospheric portions that would otherwise become too rigid to decouple.
In the wet harzburgite scenario, dehydration and metamorphic reactions are predicted to sustain zones of reduced strength within the slab, preventing it from sinking efficiently into the lower mantle. This creates a feedback loop: slower descent limits thermal loss, which in turn preserves conditions that keep the weakening processes active.
In the dry basaltic scenario, the model emphasizes that even without abundant water, basaltic mineralogy can maintain mechanical coupling over a broader depth range. The study suggests that dry assemblages may delay the development of decoupling horizons, thereby prolonging stagnation until the slab eventually transitions to a different rheological regime.
The researchers also connect their results to the observed diversity of subduction-zone behavior, where some slabs advance smoothly while others appear to linger at mantle depths. By treating rock composition explicitly rather than assuming uniform slab properties, the work offers a framework for interpreting why similar plate boundary geometries can yield markedly different slab lifetimes.
Crucially, the analysis links mineral stability, dehydration partitioning, and viscosity contrasts into a single physical narrative. This moves slab “stalling” away from a purely geometric explanation and toward a lithology-driven process that can be tested against seismic signatures.
The findings will likely influence how future models incorporate water budgets and rock types in subduction simulations. If validated by geophysical observations, the wet-versus-dry assemblage distinction could become a practical lever for predicting which slabs will stagnate and for how long.
In short, the study portrays slab stagnation as a sustained state maintained by the contrasting rheological effects of hydrated harzburgite and comparatively dry basaltic materials, reshaping our understanding of how deep Earth water and rock chemistry govern plate evolution.
Subject of Research: Subduction zone dynamics and slab stagnation mechanisms
Article Title: Slab stagnation sustained by wet harzburgite and dry basaltic slab assemblages.
A new study published in Communications Earth & Environment reports that central Tibet’s rugged mountain architecture was not built in a single burst. Instead, it was shaped by long-lived crustal shortening that persisted after a major ocean closed during the Cretaceous period—when the Bangong–Nujiang Ocean shut down and the surrounding plates collided.
The research team, led by Zhang, Liu, Lin, and colleagues, examines how tectonic forces transferred through the region during and after ocean closure. Their central finding is that shortening did not simply end when the ocean vanished. Rather, the continental collision continued to drive deformation well beyond the immediate collision event, helping sustain mountain growth over extended geological time.
To reach this conclusion, the authors combine regional tectonic constraints with structural observations that reflect how stress and strain were distributed through the Tibetan crust. They interpret the evolving patterns of deformation as evidence for sustained compression, including the way different crustal levels responded to continued convergence.
The study frames the Bangong–Nujiang Ocean closure as a pivotal tectonic switch: once the ocean disappeared, the mechanical coupling between continental blocks increased. That change allowed compression to remain effective, promoting ongoing uplift and crustal thickening in central Tibet.
Importantly, the paper links this sustained shortening to the broader development of Tibetan topography. Rather than treating uplift as a short-lived response to a single collisional moment, the results support a scenario in which post-closure tectonics kept feeding the mountain belt for millions of years.
By addressing the timing and persistence of shortening, the work helps refine how geologists explain the thick crust beneath Tibet and the coexistence of active deformation with long-term structural inheritance. The authors suggest that the region’s growth reflects both the closure of an ocean basin and the prolonged geodynamic consequences of that closure.
The findings also carry implications for how future modeling efforts should represent continental collisions. They highlight that plate-tectonic reorganizations can create enduring mechanical conditions, sustaining deformation even after the most dramatic phase of convergence has passed.
With the DOI link and citation tied to the 2026 publication, the study—understood through its title and approach—offers a clear, data-driven narrative: central Tibet’s rise reflects sustained shortening following Cretaceous ocean closure, shaping a mountain system that kept growing long after the ocean was gone.
Subject of Research: Tectonics and mountain growth in central Tibet following the Cretaceous closure of the Bangong–Nujiang Ocean
Article Title: Sustained shortening following Cretaceous Bangong–Nujiang Ocean closure shaped central Tibetan mountain growth.
Bacterial cellulose—nature’s own polymer scaffold—is gaining attention as a renewable feedstock for supercapacitor electrodes. With modern devices demanding fast charge, high power bursts, and long cycle life, researchers are searching for electrode materials that combine performance with sustainability.
A new systematic literature review led by Prof. Dahlang Tahir at Hasanuddin University, Indonesia, maps how bacterial cellulose-derived carbon (BCC) is turned into energy-storage electrodes—and why some fabrication paths outperform others. The study synthesizes evidence from the scientific record to clarify which processing choices control electrochemical behavior.
The review focuses on BCC as a precursor to porous carbon. Bacterial cellulose forms a naturally pure, interconnected network of nanoscale fibers, and heat treatment can convert that architecture into carbon structures with tunable porosity—critical for charge storage. The authors emphasize that electrical performance is not just a matter of “making carbon,” but of preserving and engineering the fiber network before carbonization.
Across 49 Scopus-indexed journal articles, the team compares major strategies including direct carbonization, chemical activation to enlarge pore systems, heteroatom doping to modify surface chemistry, and composite fabrication with materials that can add rapid redox (pseudocapacitive) contributions.
A recurring message is the importance of pre-carbonization drying. Freeze-drying appears as the most commonly used approach because it limits collapse of the wet nanofiber structure during water removal. Since pore architecture governs ion access and charge transport, maintaining nanoscale structure can translate into higher effective capacitance.
The review also distinguishes test formats. Three-electrode measurements are frequently reported, but two-electrode devices better represent real supercapacitor operation, where electrode–electrode interactions shape performance.
When processing is optimized, the results point toward a pathway for BCC-based electrodes to rival or surpass commercial activated carbon under comparable conditions. Activation and heteroatom doping generally increase accessible surface area and create additional active sites, while composites often achieve the strongest capacitance by combining electrical double-layer effects with fast surface reactions.
Yet the authors warn that progress is constrained by inconsistent experimental reporting, uneven protocols, and limited mechanistic understanding. To move beyond laboratory demonstrations, they call for predictive design, data-driven structure–performance models, scalable carbonization methods, and robust flexible devices resistant to deformation and humidity.
Subject of Research: Supercapacitor electrodes using bacterial cellulose-derived carbon Article Title: Bacterial cellulose-derived carbon electrodes for supercapacitors: Fabrication strategies, electrochemical performance, and mechanical properties — A review News Publication Date: 9 June 2026 Web References: https://doi.org/10.1016/j.est.2026.123044 References: 10.1016/j.est.2026.123044 Image Credits: Lightenoughtotravel from Wikimedia Commons
Keywords
bacterial cellulose; supercapacitors; porous carbon; freeze-drying; chemical activation; heteroatom doping; electrode materials; two-electrode testing; pseudocapacitance; sustainable energy storage
Les anticorps thérapeutiques ont déjà transformé la prise en charge de nombreux cancers et de maladies auto-immunes ou inflammatoires. Leur force : reconnaître avec une grande précision une cible biologique impliquée dans une maladie.
Viltrox has announced its new AF 26mm F2.8 EVO lens
It's available in Sony E and Nikon Z-mount versions, and costs $299 / £279
It measures 23.8mm thick and weighs 4.6oz / 130g
Chinese lens manufacturer Viltrox is having a prolific year, and it's now followed up a recent pair of medium-telephoto primes for APS-C cameras with a completely new 26mm f/2.8 pancake lens.
The AF 26mm F2.8 EVO is part of the same mid-range series as my recently tested AF 90mm F2.2 EVO, and is available for Sony E and Nikon Z-mount cameras at launch. It costs $299 / £279 (Australia price TBC).
Compact size and light weight are the aim here — the 26mm F2.8 is just 23.8mm thick and tips the scales at 4.6oz / 130g. I can see it pairing nicely with a Sony A7C / A7C II or Nikon Zf as a casual, everyday lens offering surprisingly sharp image quality.
It's not the smallest autofocus full-frame lens in Viltrox's range, mind you — that accolade goes to the AF 28mm F4.5. However, given the bright f/2.8 aperture and the features on board, the new 26mm lens seems impossibly small.
Those features include a dust- and splash-resistant machined metal construction, dedicated aperture and focus rings, a metal rear mount with a USB-C port for firmware updates, and a STM focus motor for snappy autofocus.
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And there's more: the AF 26mm F2.8 EVO ships with a magnetic lens cap that snaps into place, eliminating the fiddling that comes with traditional pinch-release lens caps.
It's part of a lens cap system which includes a magnetic lens hood, which also works with magnetic lens filters. Alternatively, traditional screw-on filters work too, via the 43mm thread.
I hope other lens manufacturers follow Viltrox's lead — lens caps can be a real pain to remove and re-attach, but a magnetic type simplifies the process.
Optically, we have a simple construction of eight elements in six groups, with a minimum focus distance of 0.2m which results in a 0.2x maximum magnification, for reasonable close-up photography.
The Viltrox AF 26mm F2.8 EVO is available immediately in Sony E and Nikon Z versions from Amazon US and Viltrox's official store. There's no word yet on whether L-mount or Fujifilm X-mount versions are on the way.
Yes, Fujifilm X is APS-C format, but I can see the full-frame Viltrox lens working well with these crop-sensor cameras, even for Sony and Nikon, on which it would offer an equivalent 39mm focal length.
It's yet another new Viltrox lens available for Nikon Z cameras, which suggests that the Nikon vs Viltrox lawsuit from earlier this year has quietly been resolved. I hope that's the case, because Viltrox has consistently produced excellent optics, and the AF 26mm F2.8 EVO looks like an impressive addition. Look out for my in-depth review, coming soon.
On Aug. 12, 2026, skywatchers across the U.K. will experience a rare astronomical double-header: a deep partial solar eclipse before sunset followed, hours later, by the peak of the annual Perseid meteor shower. Although the path of totality will sweep from Greenland and Iceland to Spain, it will miss Britain entirely. However, the solar eclipse will still be dramatic, with up to 96% of the sun obscured for viewers in the far southwest.
This will be the U.K.'s deepest partial solar eclipse since 2015, and timing will be everything. The eclipse reaches its peak around 7:00-7:16 p.m. BST, with the sun hanging low above the west-northwest horizon as a narrowing crescent shortly before sunset. Because the sun will be relatively low, choosing the right location will matter far more than traveling huge distances. Coastal viewpoints, hilltops and open landscapes with unobstructed western horizons will offer guaranteed views — if the sky is clear.
The locations below prioritize another crucial factor: dark skies. While the eclipse will be visible almost everywhere in the U.K. and most will be happy to see it from close to where they live, the real reward comes after darkness falls, when the Perseids begin flashing across the sky. Find somewhere remote, stay overnight — ideally camp — and this could become one of the most memorable observing sessions of the year.
During a partial solar eclipse, it is NEVER safe to look directly at the sun without solar eclipse glasses designed for solar viewing. Read our guide on how to observe the sun safely.
1. Hugh Town
The Isles of Scilly will see the largest eclipse in the U.K. (Image credit: Westend61 via Getty Images)
Location: St. Mary's Island, Isles of Scilly, U.K.
Max eclipse: 96.4% at 7:16 p.m. BST
Sun position: 13° above west-northwest horizon
Eclipse window: 6:19-8:10 p.m. BST
Sunset: 8:49 p.m. BST
Light pollution: 3.2 Bortle/SQM 21.86
Cloud risk: 74%
The Isles of Scilly combine Britain's deepest partial eclipse with some of southern England's darkest skies. From Hugh Town and nearby west-facing beaches on St Mary's, the eclipsed sun will hang low above the Atlantic Ocean late in the day. Later that night, with minimal light pollution and broad sea horizons, the islands are an exceptional place to watch the Perseid meteor shower beneath pristine late-summer skies.
2. Land's End
Land's End will see one of the biggest eclipses on the U.K. mainland. (Image credit: PKM1 via Getty Images)
Location: Sennen, Penzance, England
Max eclipse: 95.9% at 7:16 p.m. BST
Sun position: 13° above west-northwest horizon
Eclipse window: 6:19-8:10 p.m. BST
Sunset: 8:47 p.m. BST
Light pollution: 3.1 Bortle/SQM 21.85
Cloud risk: 71%
Land's End is one of the best places on mainland Britain to watch the eclipse because of its vast Atlantic horizon and minimal obstruction toward the west-northwest. The sun will appear heavily eclipsed as it descends toward the ocean before sunset. After dark, the remote far-western location and low levels of artificial light make this region an outstanding destination for viewing the Perseid meteor shower.
3. Boscastle
Boscastle's River Valency valley will frame the eclipsed sun. (Image credit: Graham Custance Photography via Getty Images)
Location: Cornwall, England
Max eclipse: 94.7% at 7:15 p.m. BST
Sun position: 13° above west-northwest horizon
Eclipse window: 6:18-8:09 p.m. BST
Sunset: 8:45 p.m. BST
Light pollution: 4.0 Bortle/SQM 21.71
Cloud risk: 76%
Boscastle's narrow harbor and dramatic valley may create a natural frame for the eclipsed sun as it sinks toward the Atlantic. The village's northwest-facing coastline offers clear views toward the low evening eclipse, while the surrounding Cornish countryside remains relatively dark after sunset. Once twilight fades, the cliffs and headlands nearby become excellent places to watch for bright Perseid meteors.
4. Exmoor Dark Sky Reserve
Exmoor Dark Sky Reserve is a great choice for an eclipse and the Perseids. (Image credit: Devon and Cornwall Photography via Getty Images)
Location: Exmoor National Park, Somerset and north Devon, England
Max eclipse: 93.7% at 7:14 p.m. BST
Sun position: 12° above west-northwest horizon
Eclipse window: 6:17-8:08 p.m. BST
Sunset: 8:42 p.m. BST
Light pollution: 3.9 Bortle/SQM 21.67
Cloud risk: 69%
Exmoor combines elevated moorland, dramatic coastline and protected dark skies, making it ideal for both the eclipse and the Perseids. Coastal viewpoints such as Valley of Rocks and Heddon's Mouth offer clear west-facing horizons for the low-eclipsed sun before sunset. Later that night, Exmoor's status as a Dark Sky Reserve makes it perfect for seeing bright Perseid meteors — and the Milky Way.
5. Rhossili Bay
Rhossili Bay in the Gower has a west-facing beach and dark skies at night. (Image credit: Chris Griffiths via Getty Images)
Location: Gower Peninsula, Swansea, Wales
Max eclipse: 93.8% at 7:13 p.m. BST
Sun position: 13° above west-northwest horizon
Eclipse window: 6:16-8:07 p.m. BST
Sunset: 8:46 p.m. BST
Light pollution: 4.0 Bortle/SQM 21.63
Cloud risk: 73%
Rhossili Bay's enormous west-facing beach and elevated clifftops make it ideal for watching a low eclipse unfold above the sea. Located on the Gower Peninsula, the area is a Dark Sky Community that retains relatively dark skies despite its popularity during the day. As darkness falls later that evening, the open coastal landscape provides excellent visibility for Perseid meteors.
6. Strumble Head
Strumble Head in west Wales has a clear western horizon and dark skies. (Image credit: Andrea Ricordi, Italy via Getty Images)
Location: Pencaer, Pembrokeshire, west Wales
Max eclipse: 94.0% at 7:13 p.m. BST
Sun position: 14° above west-northwest horizon
Eclipse window: 6:15-8:07 p.m. BST
Sunset: 8:51 p.m. BST
Light pollution: 3.3 Bortle/SQM 21.84
Cloud risk: 70%
Strumble Head offers one of the clearest west-facing horizons in Wales, with the eclipsed sun appearing above the Irish Sea beside its iconic lighthouse. The remote Pembrokeshire coastline experiences very little artificial light, helping preserve dark skies after sunset. Once the eclipse ends, this rugged headland becomes an excellent place to watch the Perseids, with broad ocean views and little interference from nearby towns.
7. Llŷn Peninsula
The remote Lleyn Peninsula is close to a Dark Sky Sanctuary. (Image credit: WLDavies via Getty Images)
Location: Llŷn Peninsula, Gwynedd, north Wales
Max eclipse: 93.3% at 7:11 p.m. BST
Sun position: 14° above west-northwest horizon
Eclipse window: 6:14-8:05 p.m. BST
Sunset: 8:52 p.m. BST
Light pollution: 2.9 Bortle/SQM 21.91
Cloud risk: 70%
The remote Llŷn Peninsula projects deep into the Irish Sea, offering expansive views toward the west-northwest horizon, where the eclipsed sun will appear before sunset. It is also one of the darkest regions in Wales, lying close to the protected skies of Ynys Enlli (Bardsey Island) Dark Sky Sanctuary. With minimal light pollution and wide rural vistas, the peninsula becomes a superb location for watching Perseid meteors later that same night.
8. Galloway Forest Dark Sky Park
The shore of Clatteringshaws Loch in Galloway Forest Park. (Image credit: Flavio Vallenari via Getty Images)
Location: Galloway Forest Park, Dumfries and Galloway, Scotland
Max eclipse: 91.8% at 7:07 p.m. BST
Sun position: 14° above west-northwest horizon
Eclipse window: 6:10—8:01 p.m. BST
Sunset: 8:47 p.m. BST
Cloud risk: 85%
Galloway Forest Park was Britain's first Dark Sky Park and remains one of the country's premier stargazing destinations. Open western views around Clatteringshaws Loch, along with other viewpoints away from the forests, make it well-suited to the low evening eclipse. After twilight fades, exceptionally dark skies reveal the Milky Way in striking detail, creating near-perfect conditions for viewing the Perseid meteor shower in the early hours — if the sky is clear.
9. Northumberland Dark Sky Park
Sunset at Kielder Water in Northumberland. (Image credit: Paul Hayes via Getty Images)
Location: Northumberland National Park and Kielder Water & Forest Park, Northumberland, England
Max eclipse: 90.4% at 7:07 p.m. BST
Sun position: 13° above west-northwest horizon
Eclipse window: 6:10-8:00 p.m. BST
Sunset: 8:49 p.m. BST
Light pollution: 3.3 Bortle/SQM 21.82
Cloud risk: 90%
Northumberland's Dark Sky Park combines remote landscapes with some of England's darkest skies. Locations around Kielder Water and Northumberland National Park provide broad views toward the low west-northwest eclipse shortly before sunset. Later that night, the region becomes one of the finest places in Europe to watch the Perseids, with frequent views of the Milky Way and bright meteors overhead. Check for any events at Kielder Observatory.
10. Giant's Causeway
Giant's Causeway will have a great view of the eclipse. (Image credit: Francesco Vaninetti Photo via Getty Images)
Location: Bushmills, Northern Ireland
Max eclipse: 93.1% at 7:07 p.m. BST
Sun position: 16° above the west horizon
Eclipse window: 6:09-8:02 p.m. BST
Sunset: 9:31 p.m. BST
Light pollution: 4.2 Bortle/SQM 21.52
Cloud risk: 81%
The Giant's Causeway in Northern Ireland offers a spectacular foreground for the eclipse, with the sun appearing low above the Atlantic beyond the famous basalt columns. Although the skies here are not as dark as in some rural parks, the north Antrim coastline still experiences relatively modest light pollution. Nearby coastal viewpoints and beaches provide good conditions for watching Perseid meteors later that night beneath expansive northern skies.
Que mangeaient les bâtisseurs du plus vieux village du monde, il y a 12 000 ans ? En analysant les vestiges de Karahan Tepe, en Turquie, des archéologues ont percé le secret de leur menu. Gazelle sauvage et légumineuses : le carburant, peut-être, de l'une des premières grandes aventures humaines.
Lettuce and salad greens have become the prime suspects in an explosive outbreak of the diarrheal parasite Cyclospora, which is surging nationwide but erupting to extraordinary heights in Michigan.
In recent years, Michigan has typically reported around 50 cases of cyclosporiasis, which causes urgent bouts of watery diarrhea, abdominal cramps, and nausea. But, this year, as of July 14, the state has reported 3,309 cases of the food-borne pathogen. Of those 44 have been hospitalized.
Based on interviews with more than 1,000 people sickened in Michigan, the latest data is pointing to leafy greens as the source, according to the Michigan Department of Health and Human Services (MDHHS).
Nitrogen is an essential building block of proteins, amino acids, and DNA. Without nitrogen, cells can’t function or reproduce. Nitrogen is abundant in the atmosphere as dinitrogen gas, but plants and animals can’t access atmospheric nitrogen. Instead, we rely on biologically available forms like ammonia and nitrate.
Specialized microbes can transform atmospheric nitrogen into ammonia via a process called biological nitrogen fixation. Nitrogen-fixing soil bacteria have a unique protein complex, the nitrogenase complex, that facilitates this nitrogen transformation. The nitrogenase complex is activated by a group of genes known as nif genes.
Legume plants like peanuts, peas, and beans have nitrogen-fixing bacteria in the soil zone around their roots, called the rhizosphere. The symbiotic relationship between nitrogen-fixing soil bacteria and legume plants supplies most of the biologically available nitrogen to life on Earth.
Bacteria attached to plant roots “feed” nitrogen to plants through the soil, and in turn receive organic acids for energy from plants performing photosynthesis. Source: Wikimedia Commons
However, one piece of the puzzle remains unexplored: the role of soil viruses in these nitrogen transformations, referred to as the nitrogen cycle. Viruses are microscopic particles made up of genetic material and proteins, but they can’t reproduce without a host cell. Scientists consider viruses to be biological entities that are halfway between living and non-living.
To reproduce, viruses contact a host cell and inject their genetic material into it. The virus’s genetic material takes over the host cell’s genome and forces the cell to produce proteins that assemble into new viruses. As new viruses are created, they can incorporate genes from the host cell into their own genetic material. Genes that are transferred from a host cell to a virus are known as auxiliary metabolic genes (AMGs). Viruses can carry AMGs and pass them to other hosts or use them to increase their own ecological fitness.
Scientists from China, Spain, and the Czech Republic set out to investigate whether viruses from legume roots could increase local soil nitrogen fixation by expressing nif AMGs or by transferring nif genes to other bacteria. First, they determined the global distribution of viral nitrogen-fixing genes by analyzing about 8.6 million viral genomes from the Integrated Microbial Genomes/Virus database. They looked for the DNA sequences of known nitrogen-fixing genes and the locations where the viruses were sampled. They found that only 0.003% of the viruses in the database had at least 1 nitrogen-fixing gene, but they clustered in the same locations as nitrogen-fixing bacteria.
The team also found 3 types of viruses that most commonly carried nitrogen-fixing genes: Kyanoviridae, Nudiviridae, and Bronfenbrennervirinae. Kyanoviridae viruses carried a nif gene called nifU. The researchers used a computer program called DRAM-v to confirm that nifU was a fully functional gene and a real tool that viruses could use.
Next, the team collected soil samples from a cowpea field in Nanjing, China, to test whether the cowpea roots influenced the abundance of viruses using nitrogen-fixing genes. They collected soil from the cowpea rhizospheres and soil away from the plants. They analyzed both viral and bacterial RNA in the soil samples to identify active genes, using a sequencing process called metatranscriptomics. They found that the viral nifU gene was actively expressed in the cowpea rhizosphere samples more than in the non-crop soil. Although about 96% of nifU genes were being expressed by bacteria, viruses contributed about 4%.
The researchers then assessed whether rhizospheric viruses changed the amount of nitrogen being fixed in these soils. They set up small, enclosed containers of sterile soil and added either bacteria or a mixture of bacteria and viruses extracted from the cowpea rhizospheres. They found that soil with viruses had higher total nitrogen (36 milligrams per kilogram, or mg/kg) than soil without viruses (17 mg/kg).
Finally, they adjusted the air in each container to have a different form of dinitrogen gas. Atoms of the same element that have different atomic masses are known as isotopes. Nitrogen has 2 stable isotopes: lighter nitrogen-14 and heavier nitrogen-15. Bacteria or viruses that fix nitrogen at natural isotope abundances will take up nitrogen-14. But scientists can track who in the population fixes nitrogen by adding nitrogen-15 to the air, a process called nitrogen-15 stable isotope probing. Nitrogen-fixers will incorporate the heavy nitrogen-15 into their biomass over time and increase their weight, allowing researchers to separate and identify them.
The team grew the bacteria and viruses with nitrogen-15 for 35 days, then used stable isotope probing to separate the nitrogen fixers. They detected viral nifU AMGs among the heavier biomass, confirming that rhizospheric viruses were fixing nitrogen.
The team concluded that rhizospheric viruses and the viral nifU AMG can increase nitrogen fixation in cowpea soils. The team suggested that although viruses with nitrogen-fixing genes are rare, they can influence the soil nitrogen cycle. They recommended that future researchers further test the contribution of viral nifU genes to plant nitrogen fixation with controlled infection experiments.
One month from today, millions will turn their eyes to the skies for one of the most anticipated skywatching events of the year: the total solar eclipse on Aug. 12, 2026.
The eclipse will sweep across parts of Greenland, Iceland and Spain, briefly turning day into night for those lucky enough to be within the narrow path of totality.
It's been a long time coming for European skywatchers, as the event marks Europe's first total solar eclipse since 1999.
Where can I see the total solar eclipse?
If you're hoping to experience totality, now is the time to finalize your plans. Thepath of totality crosses Greenland, Iceland and northern Spain, with maximum eclipse lasting up to 2 minutes and 18 seconds.
Path of totality over Iceland.Created using MapHub.net. Source: Esri, Maxar, GeoEye, Earthstar Geographics, CNES/Airbus DS, USDA, USGS, AeroGRID, IGN, and the GIS User CommunityPath of totality over Spain.Created using MapHub.net. Source: Esri, Maxar, GeoEye, Earthstar Geographics, CNES/Airbus DS, USDA, USGS, AeroGRID, IGN, and the GIS User CommunityEntire path of totality. From Greenland through Iceland and Spain. Created using MapHub.net. Source: Esri, Maxar, GeoEye, Earthstar Geographics, CNES/Airbus DS, USDA, USGS, AeroGRID, IGN, and the GIS User Community
Spain is expected to be one of the most popular destinations thanks to its favorable weather prospects, though it's not without a catch! Viewers will need to secure a clear view of the western horizon because the eclipsed sun will sit very low in the sky during totality.
Notable locations and timings of totality
Location
Totality duration
What time?
Sun height
Scoresby Sund, Greenland
1 minute, 46 seconds
4:35 p.m. CGST
24 degrees above west
Reykjavik, Iceland
1 minute, 1 second
5:48 p.m. GMT
25 degrees above west
Snæfellsjökull National Park, Iceland
2 minutes, 10 seconds
5:45 p.m. GMT
25 degrees above west
Gijón, Spain
1 minute, 46 seconds
8:26 p.m. CEST
10 degrees above west-northwest
A Coruña, Spain
1 minute, 15 seconds
8:27 p.m. CEST
12 degrees above west-northwest
Palencia, Spain
1 minute, 42 seconds
8:29 p.m. CEST
9 degrees above west-northwest
Burgos, Spain
1 minute, 44 seconds
8:28 p.m. CEST
8 degrees above west-northwest
Segovia, Spain
54 seconds
8:31 p.m. CEST
8 degrees above west-northwest
Sigüenza, Spain
1 minute, 38 seconds
8:30 p.m. CEST
7 degrees above west-northwest
Mallorca, Balearic Islands, Spain
1 minute, 36 seconds
8:31 p.m. CEST
2.7 degrees above west-northwest
Will I see the eclipse from where I live?
Not inside the path of totality? Don't worry. A spectacular partial solar eclipse will be visible across much of Europe, with more than 90% of the sun covered from locations including London, Paris and Dublin.
Over the coming weeks, Space.com will bring you everything you need to prepare for eclipse day. We'll publish viewing guides, safety advice and information on how to watch the eclipse online.
Closer to the event, we'll launch a dedicated live blog covering the latest eclipse news and insights from our reporters in the field.
Skywatching Editor Daisy Dobrijevic will join an eclipse expedition to Greenland with HX, while Skywatching Writer Anthony Wood will travel to northern Spain with the DEB initiative and citizen scientists to report firsthand from the path of totality.
The symptoms: The man sought medical attention at a hospital because the muscles on one side of his face had weakened suddenly, causing it to droop — a condition called unilateral peripheral facial-nerve palsy. He had also recently had a fever, which had since resolved.
Tests run by the neurology department found the man had anemia, fatty liver disease and an enlarged spleen. Combined with his recent fever, these findings led the team to assume he had a viral infection. However, he tested negative for a variety of germs, including Epstein-Barr virus, which causes mono; cytomegalovirus; human immunodeficiency virus (HIV); and hepatitis A, B, C, and E.
The man's liver abnormalities hadn't resolved by one week later, but his facial-nerve palsy cleared following a 10-day course of a strong corticosteroid. But then, over the next month, the man's knees and ankles became stiff and painful, and his legs and feet — and occasionally his face, arms and hands — began to swell. He reported feeling generally unwell, he had gained 11 pounds (5 kilograms), and his urine had darkened even though he had been drinking more water than usual. All of these signs pointed to problems with his kidney function.
Besides the conditions uncovered on his recent medical examinations, the patient had long-standing high blood pressure, high cholesterol, an enlarged prostate and chronic obstructive pulmonary disease (COPD), for which he was taking medications. He had also been diagnosed with rectal cancer 20 years beforehand and received various treatments over the years. He and his wife of 50 years had been sexually inactive since that cancer treatment, he told his doctors.
What happened next: After weeks spent in and out of the hospital, the man went to an emergency room after his skin suddenly became intensely itchy. He had a red, scaly rash on his calves. A neurological exam revealed "normal motor strength, sensation, reflexes, coordination, and gait," the doctors wrote in a report of the case.
At the ER, the patient was questioned further about his medical history, at which point he told doctors that, during his military service as a young man, he'd had unprotected sex with multiple casual partners. He reported being treated for various sexually transmitted infections (STIs) during that time but had forgotten the specific diagnoses.
Tests revealed that the patient was anemic and that his urine contained blood and an abnormal amount of protein. Additionally, a test for autoimmune diseases found abnormally high levels of antinuclear antibodies, which target the control centers of cells that house DNA. Because the patient had recently had facial-nerve palsy, the doctors analyzed his cerebral spinal fluid — the clear fluid that surrounds the brain and spinal cord. This revealed elevated levels of white blood cells, which hinted at an active infection.
The diagnosis: While tests for HIV and tuberculosis came back negative, an assay for Treponema pallidum, the bacterium that causes syphilis, was positive, confirming that the patient had an active syphilis infection.
Syphilis infections can progress through four stages, each with different symptoms. If an infected person doesn't get effective treatment during the primary and secondary stages, the bacteria can go latent, sometimes for decades. And in a minority of cases, latent syphilis can awaken and cause a late, or tertiary, infection.
A more recent, unreported exposure must be considered.
Based on his positive T. pallidum test, rash, general unwell feeling, abnormal liver results, high urinary protein count, leg swelling, facial drooping and swollen lymph nodes, the man's doctors diagnosed him with secondary syphilis with early neurosyphilis, in which the bacteria attack the nervous system.
The treatment: The patient had been given a single injection of penicillin before the test results confirmed that his infection had neurological involvement. He was subsequently given a 14-day course of intravenous penicillin, which is the recommended treatment for neurosyphilis, according to the case report.
The severe itching was treated with antihistamines, and he was prescribed diuretics to reduce the swelling in his legs. The rash, itching and swelling had improved by his one-month follow-up appointment, and his liver tests and urinary output had normalized.
Public health authorities were informed of the patient's diagnosis, and his wife was referred for testing. The case report does not note whether his wife tested positive for syphilis.
What makes the case unique: Secondary syphilis normally occurs within the first year of an untreated infection and only rarely develops after four years have passed. Normally, smooth, hard sores appear on the mouth or genitals during primary syphilis, and once those sores disappear, secondary syphilis sets in within months, if left untreated.
"Although the patient's history of multiple sexually transmitted infections as a young man prompted testing for syphilis, an exposure from that period would not be expected to explain his current presentation," his doctors wrote.
There's a possibility that the man had a latent infection that recently reactivated, perhaps due to the immune-suppressing effect of his recent steroid treatment. But you'd expect the reactivation to cause only symptoms of tertiary syphilis — like nervous system problems — not symptoms associated with secondary syphilis, like fever, rash and weight loss.
Therefore, exactly when the man contracted the infection is uncertain. "A more recent, unreported exposure must be considered," the doctors wrote.
A years-long malaria control campaign in the Brazilian Amazon nearly eliminated the disease from a city — but then cases rebounded. Now, scientists think they've uncovered why.
The campaign took place in northern Brazil during the construction of the Belo Monte Dam in the Xingu River, one of the largest hydroelectric dams in the world. From 2013 to 2017, the initiative slashed annual malaria rates from more than 1,200 cases to fewer than 60. But the program ended, and within a few years, infections had rebounded to more than 700 cases a year. This time, they were concentrated in the rural communities surrounding the river in the city of Altamira.
In a study published Thursday (July 9) in the journal GeoHealth, scientists analyzed 15 years of malaria surveillance records alongside satellite images of forests around Altamira. Earlier studies have pointed to deforestation and dam construction as a driver of malaria because they can provide habitats for mosquito larvae, which inhabit the forest edge. In Altamira, large stretches of rainforest have been cleared for cattle ranching, logging and settlement along the Xingu River in the decades since the region was first opened up by road-building, leaving a patchwork of cleared land pressed up against the remaining forest.
However, the study found that the malaria resurgence wasn't simply a result of how much forest had been cut down. Instead, cases tracked most closely with the forest edge, the boundary where intact forest meets cleared or open land. There, mosquitoes get everything they need to thrive: shade from the tree line, sunlit pools of standing water for their larvae, and people living or working close by.
The findings highlight how the environment contributes to malaria risk, suggesting that maintaining surveillance in these high-risk landscapes could be just as important as driving cases down in the first place.
"What made Altamira compelling was that the timing gave us something rare, close to a natural experiment," study co-author Eloise Skinner, an epidemiologist and postdoctoral research fellow at the University of Queensland in Australia, told Live Science in an email. The results of that natural experiment could help Brazil in its efforts to eliminate malaria from the country in the next decade, she said.
A program tied to temporary funding
The researchers tracked malaria trends before, during and after the construction of the Belo Monte Dam. Before construction began, malaria was already a persistent problem in the region; Altamira city alone reported more than 1,200 cases a year.
As thousands of workers moved in, local health authorities and the dam's developers rolled out an intensive control program that involved spraying insecticides indoors, using mosquito nets, and deploying rapid diagnosis and treatment when cases did emerge. The goal was to head off outbreaks spread by Nyssorhynchus darlingi, the mosquito that carries the malaria-causing parasite in the Brazilian Amazon.
Mosquitoes pick up the parasite that causes malaria by feeding on the blood of infected people, and they can then spread that parasite to others they bite. Treating infected people quickly can help break that chain of transmission.
Cases plummeted despite the influx of workers, but once construction wrapped up and the program lost its funding, malaria came back.
Nyssorhynchus darlingi, the mosquito that spreads malaria in the Amazon, breeds in partially shaded bodies of water. (Image credit: Sabrina Simon)
To understand what drove the resurgence, the researchers combined three streams of data. Case records came from Brazil's national malaria surveillance system and covered 150 health centers in Altamira over 15 years. The team layered on temperature, forest cover and rainfall data, since both shape how favorable an area is for mosquito breeding and how efficiently the malaria parasite develops inside mosquitos. Plus, they added an estimate of travel time between each cluster of cases and the nearest town, as a proxy for how easily people and the diseases they carry might move around.
From the observations, the forest edge consistently emerged as the strongest predictor of increased malaria cases. For every 1% increase in the perimeter of the forest edge, malaria cases rose by roughly 0.7%; for every 1% increase in Altamira's population, who are located at the forest edge, cases rose by about 1.4%.
The rebound wasn't evenly distributed. Before the dam was built, most of Altamira's malaria cases came from clusters inside the city itself. Afterward, that pattern flipped: by 2020, the roughly 700 annual cases were concentrated almost entirely in remote, rural clusters near forest edges. Meanwhile, Altamira's urban center stayed comparatively protected, much as it had during construction.
"When the funded program wound down, malaria came back to the communities that are hardest for the health system to reach," Skinner said. "The city stayed protected, most likely because fast diagnosis and treatment are easier to deliver and keep going in a town."
That leaves the same communities exposed twice over, Skinner said. The places that are already the hardest to reach with health services also sit where the ecological risk is the highest.
But this pattern could point to solutions. The resurgence didn't scatter unpredictably. It came back to the same kind of place — rural communities at the forest edge — each time. That's the kind of risk that can be anticipated in the future.
Brazil aims to eliminate locally acquired malaria by 2035. Skinner said Altamira's near elimination of the disease, and its rebound within a few years of the control program ending, is a warning for that effort. When a community contains a strong environmental driver for malaria, like forest-edge ecosystems, stopping a control program short is sure to let the disease climb back.
"Because the resurgence wasn't diffuse, we can predict where malaria is likely to return first," Skinner said. "The message for a 2035 goal isn't only that elimination needs sustained investment. It is that where the environment drives risk, that risk is predictable, and planning for it from the start is what lets the money go where it matters most."
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