Meet ERNEST, NASA’s Next-Generation Rover Designed to Be Faster and Tougher


One new mission is setting out to study menstruation in microgravity for the first time ever.
Forty-six years ago, NASA engineers asked Sally Ride if 100 tampons was the right amount to send with her for a six-day spaceflight. Though people laugh at that fact today, there has still never been any scientific study dedicated to studying menstruation in space. But a non-profit called Operation Period aims to change that. Led by Gen-Z researchers, this non-profit works to provide what its founder Manju Bangalore calls "menstrual freedom," which she says would mean everyone can have easy access to menstrual products. Meanwhile, the organization also aims to tackle the wider issues that leave people without such access in the first place. With its upcoming suborbital mission Operation Period-01 (OP-01), this ambitious team is taking their cause into microgravity. On OP-01, the mission's founder will launch to space to conduct the research themselves on a Virgin Galactic suborbital flight in 2027.
In conducting their work here on Earth, Operation Period found that "there were still some of those same gaps in spaceflight medicine," Manju Bangalore, the founder and executive director of Operation Period and research astronaut in training for OP-01, told Space.com. " I want all menstruators to be able to live life with their full dignity and reach their fullest potential, and that includes astronauts."
With a background in physics and astronomical engineering as well as with training in bioastronautics and having spent time working at NASA, Bangalore brings her love of space to this cause. She and Priya Abiram, the Director of Research at Operation Period's Redshift Lab, feel so strongly about their message, even 9 years since the pair founded their non-profit; in fact, with this mission, the two will become some of the youngest South Asian women to travel to space.
"On a personal level, I've always been fascinated by space and human space exploration. It's what's always excited me as a child, and I've kept that curiosity going," Bangalore said. "I didn't think those two missions would ever combine into this. It wasn't something I ever planned, but I'm very grateful to lead this historic mission to advance menstrual health in this way."
And just as this team is excited to bring their research into a suborbital environment, Virgin Galactic is excited to be expanding the range of microgravity science the non-profit supports. "This mission with Operation Period is a powerful example of how Virgin Galactic can continue to support real-time, in-flight scientific investigation into long-overlooked areas of human health, helping advance more inclusive and innovative exploration that delivers insight for both space and life on Earth," Virgin Galactic director of system analysis & research Amber Favaregh said in an emailed statement.
Recently, Operation Period expanded to include a research wing, and this mission will be conducted under that umbrella. The team was not yet able to share specific details on the exact protocol that will be conducted during the mission, information they said will be shared at a date closer to launch, but they did share the current issues that this research aims to begin to address.
Currently, astronauts typically choose to fully suppress their periods during their spaceflights, through hormonal IUDs or oral contraceptive pills. While that is a choice astronauts might continue to make in the future, without data to show the reality of dealing with a period in space, astronauts are left with fewer choices with their own bodies. Comprehensive data on menstruation in space will also be important if astronauts are to complete longer spaceflights or even extended stays on the moon. While the mission has not yet revealed its priorities and exactly what data it will collect, with such limited data on menstruation in space, there is a lot of knowledge to be gained.
While "the data that we have, although limited, says that it is generally safe to menstruate, in terms of long duration missions, we don't have quantitative data," Bangalore said. "We don't have enough data to continue to assist with patient resource allocation for mission planners."
Historic missteps like the "100 questions" moment with Sally Ride highlight an issue that could have big effects on future, longer-term missions. Sure, having a ridiculous number of backup products would ensure that there is no need unaddressed, mass considerations for spaceflight are extremely serious and future missions will need to have better data to know what will be needed in a microgravity environment.
And just like with other science in space, the research conducted in microgravity will also be used on Earth. The pair aim to collect menstruation data that will benefit astronauts as well as people back on our home planet. .
"I think on Earth, there's a lot of gaps right now in menstrual health research," Bangalore said. As just one example, she cited recent findings that menstrual product companies were reporting incorrect absorbency of their products because they were testing products with saline, which is very different from menstrual blood. "This was potentially leading to doctors to underdiagnosed heavy menstrual bleeding, which right now the stats say affects 20% of American menstruators," Bangalore said.
With this being the first mission of its kind, OP-01 will not answer every question that remains about menstruation and space, but it will bring data to a conversation decades in the making. "Our hope is to continue to iterate this research so that we can do future suborbital flights, as well as orbital flights, to continue to create larger data sets," Bangalore said. "I think the point of preliminary studies is to be able to know what questions to ask in the future, so we don't expect that this suborbital flight will solve everything or create all the data that we need, right, but we hope that this will be a good stepping stone."
Momentum for this research was actually sparked by many millions of views on a viral social media video in which Bangalore conducted an early version of a menstrual fluid dynamic experiment in a low-gravity environment aboard a parabolic flight.
This viral moment "ended up being a really cool kind of 'in' to continue talking about destigmatizing periods," she said. "Through that, I got to talk more about the gaps in spaceflight medicine, in terms of menstrual health."


It's Juneteenth in the U.S. today (June 19), a federal holiday that commemorates the end of slavery in America.
Though the Civil War ended in April of 1865, it wasn't until June 19 that same year when Union soldiers officially enforced the law that all enslaved people would be free. But the end of slavery was only the beginning of the challenges soon to follow; for one, segregation between Black and white people in the U.S., both systemic and informal, persisted for years. And we still live in a time when active racism, and the consequences of prior racism, trickle into many aspects of society.
It indeed affected NASA; Black women at the agency were once discriminated against despite making serious contributions to the space program. Our image of the day today celebrates the accomplishments of one such woman, Annie Easley.
In 1955, Annie Easley started working for NASA's predecessor organization, the National Advisory Committee for Aeronautics (NACA). Her job was to serve as a "human computer," which was a position unique to the time. (NACA was dissolved in 1958, and its duties and personnel were taken on by the newly created NASA.)
Human computers at NACA and NASA were women who worked as basically early versions of computer programmers. To be a human computer, you had to be extremely good at mathematics, performing reliable calculations on a consistent basis to aid space missions.
Eventually, though, NASA moved toward the use of machine computers more often; Easley transitioned along with the space agency, ultimately becoming a full-fledged computer programmer.
As NASA explains, Easley's career shifted once again as it progressed. After some time, she took a position as the space agency's EEO, or Equal Employment Opportunity, counselor. She worked with NACA/NASA for 34 years before retiring in 1989. She passed away in 2011.
Like Easley, many of NASA's human computers became computer programmers once the agency made the transition to relying more heavily on machine computers. They together performed hundreds of thousands of calculations for the space program.
Easley alone was able to develop code that was crucial in research of energy-conversion systems, which paved the way for hybrid vehicles like the Centaur upper-stage rocket. Down the line, this work of hers contributed to the 1997 launch of the Cassini spacecraft that headed to Saturn.
However, the story wasn't as golden as it sounds retrospectively. Though NACA started hiring white women as "computers" in 1935, the agency didn't begin allowing Black women to enter the workforce until 1943. And that was only due to a shortage of professionals because of World War 2. In fact, human computers at the agency were not called professionals but rather "subprofessionals," and they were regularly talked down to by men who worked at the organization.
Black women had it particularly bad: They had to jump through hoops imposed by both racism and sexism.
Easley was one of just four African Americans out of 2,500 employees at NACA when she was hired.
In a 2001 interview, Easley recalled her mother saying to her: "'You can be anything you want to. It doesn't matter what you look like, what your size is, what your color is. You can be anything you want to, but you do have to work at it.'"
"I still believe that," she said.
A Yale-led study uncovered unexpected communication between retinal visual pathways that were thought to operate separately. Researchers at Yale School of Medicine (YSM) have discovered unexpected insights into how the eye handles visual information. When we view a scene, the visual system quickly separates different features, including color, contrast, and motion, and processes them independently. [...] 

Sally Ride made history aboard the Space Shuttle Challenger on June 18, 1983, becoming the first American woman in space 20 years nearly to the day after Soviet Valentina Tereshkova’s flight. In 1977, as she was finishing her Ph.D. in physics, Ride saw a newspaper ad placed by NASA to recruit astronauts. For the firstContinue reading "June 18, 1983: Sally Ride is the first American woman in space"
The post June 18, 1983: Sally Ride is the first American woman in space appeared first on Astronomy Magazine.
6 min read
A new study of two supernova remnants, the debris left behind after stars explode, suggests the explosions came from stellar siblings that once orbited each other. The first star’s detonation sent its binary companion hurtling through space, and then, after traveling for thousands of years, the surviving star blew up too.

“Using 16 years of data from NASA’s Fermi Gamma-ray Space Telescope, our analysis uncovered gamma rays associated with a supernova remnant that was hidden in the glare of its neighbor, the Jellyfish Nebula, one of the brightest gamma-ray-emitting supernova remnants known,” said Miltiadis Michailidis, a postdoctoral fellow in the physics department at Stanford University in California. “There are so many striking connections between the two remnants that we conclude they’re likely related, giving us the first known example of a binary system where both stars have undergone supernova explosions.”
Michailidis presented the findings Wednesday at the 248th meeting of the American Astronomical Society in Pasadena, California. A paper describing the results will appear in a future edition of Nature Communications.
The study focused on a faint supernova remnant called G189.6+3.3, which is mainly visible in X-rays. It is upstaged by its brighter and better-known neighbor, the Jellyfish Nebula (IC 443). The two star wrecks, both located in the constellation Gemini, appear to partially overlap as seen in X-rays. Recent X-ray evidence suggests that hot plasma likely associated with G189.6+3.3 may extend across the entire region, a hint that the overlap may be nearly total.
A massive star explodes when its energy-producing core runs out of fuel and collapses under its own weight, triggering an explosion that blows the star apart. The explosion’s shock wave encloses a hot cloud of debris that rapidly expands into space. So far, astronomers have cataloged about 300 supernova remnants in our galaxy.
The Fermi mission is part of NASA’s fleet of observatories monitoring the changing cosmos to help humanity better understand how the universe works. More than a decade ago, observations from Fermi’s LAT (Large Area Telescope) showed that the shock waves of supernova remnants accelerated particles to within a fraction of the speed of light, a process first proposed by physicist Enrico Fermi — the mission’s namesake — in 1949.
These high-speed particles, called cosmic rays, interact with interstellar gas to produce gamma rays, the highest-energy form of light. Protons make up 99% of cosmic ray particles. To prove that accelerated protons are responsible for the glow, astronomers search for a specific gamma-ray feature. When cosmic-ray protons smash into interstellar gas, they produce a short-lived particle called a neutral pion, which almost immediately decays into a pair of gamma rays. This emission occurs within a specific band of energies associated with the neutral pion’s mass and lies within the range detected by Fermi’s LAT instrument.
In 2013, Fermi observations proved that the Jellyfish Nebula, which is interacting with part of a glowing cloud of hydrogen gas known as Sharpless 249, produced gamma rays through this mechanism. Its neighbor, G189.6+3.3, was discovered in 1994 as part of an X-ray survey by the German-led ROSAT (Roentgen Satellite) mission.
A bright filament of gas lies between the overlapping remnants. New observations of this feature reveal that the shock wave from G189.6+3.3 slammed into dense interstellar gas there and dramatically slowed, key evidence that both remnants are interacting with the same cloud system.

Astronomers think the Jellyfish Nebula is also a candidate PeVatron, a cosmic particle accelerator capable of boosting protons to energies so high they could nearly escape our galaxy. Such particles can produce gamma rays with trillions of times more energy than visible light. Finding a second particle accelerator near the Jellyfish Nebula could offer scientists new clues for how supernova remnants develop into PeVatrons.
“The overlapping remnants, a connecting gas filament, and the availability of data from Fermi and other facilities motivated us to delve into this complex but little-studied region,” said co-author Marianne Lemoine-Goumard, an astrophysicist at the French National Centre for Scientific Research (CNRS) based at the University of Bordeaux. “With Fermi’s LAT instrument, we found gamma-ray emission associated with accelerated protons in the northern part of the fainter remnant. If both remnants are interacting with the same structure, then they must share a common distance from us.”
The team concludes the remnants lie about 6,000 light-years away, their explosion centers are separated by roughly 40 light-years projected onto the plane of the sky, and the original stars may have been 20 or more times the Sun’s mass.
Estimates of the remnants’ ages vary widely, but the team concludes that the age of the Jellyfish Nebula is 8,000 to 9,000 years, while G189.6+3.3 is between 20,000 to 110,000 years old. This means the delay between the explosions could have extended for up to 100,000 years.
In addition, the team conducted computer simulations of a million massive binary systems. They show that systems where the stars orbit close enough to exchange matter and interact during their lives can readily produce dual supernova explosions with similar separations and time delays as those found for the remnants. The team also estimated that the chance of randomly encountering this combination of observed spatial alignment and compatible distances to be less than 1%, strongly supporting a physical association.
“The evidence we’ve compiled — including observations across the spectrum, the chemical and physical properties of the remnants, simulations, and more — paints a compelling picture of a dual supernova event,” said Michailidis.
This study identifies a unique possible example of a binary system where both stars exploded as supernovae and left behind separate, detectable supernova remnants. Astronomers think that most massive stars form in binary or multiple-star systems. The Jellyfish Nebula/G189.6+3.3 complex offers astronomers a rare opportunity to study how massive binary stars evolve, exchange matter, explode, and experience velocity changes — called kicks — induced by the supernova blast. It also provides a powerful new laboratory for understanding how coupled supernova remnants behave, including how they accelerate particles, generate gamma rays, and shape their surrounding environments.
“Fermi’s gamma-ray observations of supernova remnants continue to reveal the dynamic lives of stars,” said Elizabeth Hays, the Fermi project scientist at NASA’s Goddard Space Flight Center in Greenbelt, Maryland. “We can now connect the glowing remains of two massive stars to a powerful pair that evolved together over thousands of years.”
By Francis Reddy
NASA’s Goddard Space Flight Center, Greenbelt, Md.
Media Contact:
Claire Andreoli
301-286-1940
NASA’s Goddard Space Flight Center, Greenbelt, Md.


6 min read
A new study of two supernova remnants, the debris left behind after stars explode, suggests the explosions came from stellar siblings that once orbited each other. The first star’s detonation sent its binary companion hurtling through space, and then, after traveling for thousands of years, the surviving star blew up too.

“Using 16 years of data from NASA’s Fermi Gamma-ray Space Telescope, our analysis uncovered gamma rays associated with a supernova remnant that was hidden in the glare of its neighbor, the Jellyfish Nebula, one of the brightest gamma-ray-emitting supernova remnants known,” said Miltiadis Michailidis, a postdoctoral fellow in the physics department at Stanford University in California. “There are so many striking connections between the two remnants that we conclude they’re likely related, giving us the first known example of a binary system where both stars have undergone supernova explosions.”
Michailidis presented the findings Wednesday at the 248th meeting of the American Astronomical Society in Pasadena, California. A paper describing the results will appear in a future edition of Nature Communications.
The study focused on a faint supernova remnant called G189.6+3.3, which is mainly visible in X-rays. It is upstaged by its brighter and better-known neighbor, the Jellyfish Nebula (IC 443). The two star wrecks, both located in the constellation Gemini, appear to partially overlap as seen in X-rays. Recent X-ray evidence suggests that hot plasma likely associated with G189.6+3.3 may extend across the entire region, a hint that the overlap may be nearly total.
A massive star explodes when its energy-producing core runs out of fuel and collapses under its own weight, triggering an explosion that blows the star apart. The explosion’s shock wave encloses a hot cloud of debris that rapidly expands into space. So far, astronomers have cataloged about 300 supernova remnants in our galaxy.
The Fermi mission is part of NASA’s fleet of observatories monitoring the changing cosmos to help humanity better understand how the universe works. More than a decade ago, observations from Fermi’s LAT (Large Area Telescope) showed that the shock waves of supernova remnants accelerated particles to within a fraction of the speed of light, a process first proposed by physicist Enrico Fermi — the mission’s namesake — in 1949.
These high-speed particles, called cosmic rays, interact with interstellar gas to produce gamma rays, the highest-energy form of light. Protons make up 99% of cosmic ray particles. To prove that accelerated protons are responsible for the glow, astronomers search for a specific gamma-ray feature. When cosmic-ray protons smash into interstellar gas, they produce a short-lived particle called a neutral pion, which almost immediately decays into a pair of gamma rays. This emission occurs within a specific band of energies associated with the neutral pion’s mass and lies within the range detected by Fermi’s LAT instrument.
In 2013, Fermi observations proved that the Jellyfish Nebula, which is interacting with part of a glowing cloud of hydrogen gas known as Sharpless 249, produced gamma rays through this mechanism. Its neighbor, G189.6+3.3, was discovered in 1994 as part of an X-ray survey by the German-led ROSAT (Roentgen Satellite) mission.
A bright filament of gas lies between the overlapping remnants. New observations of this feature reveal that the shock wave from G189.6+3.3 slammed into dense interstellar gas there and dramatically slowed, key evidence that both remnants are interacting with the same cloud system.

Astronomers think the Jellyfish Nebula is also a candidate PeVatron, a cosmic particle accelerator capable of boosting protons to energies so high they could nearly escape our galaxy. Such particles can produce gamma rays with trillions of times more energy than visible light. Finding a second particle accelerator near the Jellyfish Nebula could offer scientists new clues for how supernova remnants develop into PeVatrons.
“The overlapping remnants, a connecting gas filament, and the availability of data from Fermi and other facilities motivated us to delve into this complex but little-studied region,” said co-author Marianne Lemoine-Goumard, an astrophysicist at the French National Centre for Scientific Research (CNRS) based at the University of Bordeaux. “With Fermi’s LAT instrument, we found gamma-ray emission associated with accelerated protons in the northern part of the fainter remnant. If both remnants are interacting with the same structure, then they must share a common distance from us.”
The team concludes the remnants lie about 6,000 light-years away, their explosion centers are separated by roughly 40 light-years projected onto the plane of the sky, and the original stars may have been 20 or more times the Sun’s mass.
Estimates of the remnants’ ages vary widely, but the team concludes that the age of the Jellyfish Nebula is 8,000 to 9,000 years, while G189.6+3.3 is between 20,000 to 110,000 years old. This means the delay between the explosions could have extended for up to 100,000 years.
In addition, the team conducted computer simulations of a million massive binary systems. They show that systems where the stars orbit close enough to exchange matter and interact during their lives can readily produce dual supernova explosions with similar separations and time delays as those found for the remnants. The team also estimated that the chance of randomly encountering this combination of observed spatial alignment and compatible distances to be less than 1%, strongly supporting a physical association.
“The evidence we’ve compiled — including observations across the spectrum, the chemical and physical properties of the remnants, simulations, and more — paints a compelling picture of a dual supernova event,” said Michailidis.
This study identifies a unique possible example of a binary system where both stars exploded as supernovae and left behind separate, detectable supernova remnants. Astronomers think that most massive stars form in binary or multiple-star systems. The Jellyfish Nebula/G189.6+3.3 complex offers astronomers a rare opportunity to study how massive binary stars evolve, exchange matter, explode, and experience velocity changes — called kicks — induced by the supernova blast. It also provides a powerful new laboratory for understanding how coupled supernova remnants behave, including how they accelerate particles, generate gamma rays, and shape their surrounding environments.
“Fermi’s gamma-ray observations of supernova remnants continue to reveal the dynamic lives of stars,” said Elizabeth Hays, the Fermi project scientist at NASA’s Goddard Space Flight Center in Greenbelt, Maryland. “We can now connect the glowing remains of two massive stars to a powerful pair that evolved together over thousands of years.”
By Francis Reddy
NASA’s Goddard Space Flight Center, Greenbelt, Md.
Media Contact:
Claire Andreoli
301-286-1940
NASA’s Goddard Space Flight Center, Greenbelt, Md.
The post NASA’s Fermi Mission Uncovers Possible Sibling Supernova Remnants appeared first on NASA Science.

In a groundbreaking advancement that could reshape the landscape of bioelectronic medicine, researchers have developed a wirelessly powered, bioresorbable electrical stimulation system with unprecedented programmable control over stimulation waveforms. This innovation integrates tissue-penetrating near-infrared (NIR) light to modulate electrical currents with precision, harnessing a novel bioresorbable silicon phototransistor as the cornerstone of its operation. Pioneering beyond earlier monophasic pulse devices, this technology allows for the delivery of monophasic, biphasic, and polyphasic stimulation patterns, significantly enhancing the versatility and therapeutic potential of implantable electrical stimulators designed to dissolve harmlessly after use.
Traditional electrical stimulators implanted in biological tissues have largely relied on wired connections or bulky batteries, impeding patient mobility and often necessitating additional surgeries for device removal. Bioresorbable devices emerged as a solution to these challenges by safely degrading in the body over time, eliminating the risks associated with permanent implants. However, these earlier systems primarily delivered monophasic pulses, limiting therapeutic precision and adaptability in complex treatments. The innovation reported by Kim, Seo, Wang, and colleagues introduces a new paradigm by integrating wireless power transfer via NIR light and programmable waveform control within a fully bioresorbable platform, thus extending the functional range and easing the clinical management of bioelectronic therapies.
Central to this system is the incorporation of bioresorbable silicon phototransistors engineered to serve as optoelectronic modulators within the electrical circuitry. When illuminated by externally applied near-infrared light that penetrates deep into biological tissues, these phototransistors effectively adjust current flows at critical circuit nodes. This optical modulation capability replaces conventional electronic control elements, which often rely on persistent power sources or invasive wiring, thereby enabling the device to operate autonomously while still allowing fine-tuning of stimulation parameters through non-contact optical inputs.
The adoption of near-infrared light as the wireless power and control mechanism is particularly significant. NIR light possesses the ability to penetrate through several centimeters of tissue without causing damage, providing a safe and efficient transmission channel between the external controller and the implanted device. This feature supports programmability in situ, empowering clinicians to tailor electrical stimulation waveforms dynamically after device implantation. Precisely controlling the shape, amplitude, and timing of the electrical pulses is crucial for optimizing therapeutic outcomes in applications such as neuroregeneration and cardiac pacing.
The research team demonstrated the remarkable versatility of their bioresorbable system by successfully delivering a variety of stimulation waveforms. Monophasic pulses, which are unidirectional current flows, serve as a baseline therapy. More complex biphasic and polyphasic waveforms, which alternate current direction and comprise multiple phases respectively, have been shown to minimize tissue damage and improve efficacy in various biosignaling contexts. The ability to generate these sophisticated patterns expands the therapeutic range of the device, potentially enabling treatments that were previously inaccessible using bioresorbable technologies.
In demonstrating practical utility, the device was tested in both small and large animal models, validating its capacity for clinically relevant electrical stimulation regimes. The system was effectively employed in single- and dual-chamber cardiac pacing, a critical intervention for managing arrhythmias and heart block. Through controlled electrical stimulation, the device could synchronize cardiac contractions, a feat crucial for restoring efficient cardiac output. These trials highlight the translational potential of the technology for future human applications, situating it as a promising alternative to current electronic pacemakers that require permanent implantation and battery replacements.
Further extending the functional scope, the researchers utilized the bioresorbable stimulator to activate phrenic neuromuscular pathways to either induce or block diaphragmatic movements. The phrenic nerve controls diaphragmatic excursion, essential for respiration, and its modulation has significant implications for respiratory therapies, such as in patients with spinal cord injuries or central hypoventilation syndromes. By enabling wireless, programmable neurostimulation of the phrenic nerve, the technology offers a minimally invasive approach to manage life-sustaining respiratory functions, with the added benefit of device degradation after the therapeutic window.
The bioresorbable nature of the silicon phototransistors and associated electronics assures that after fulfilling their therapeutic role, the devices gradually dissolve into biocompatible byproducts. This process circumvents the complications related to device explantation surgeries, reducing patient risk and healthcare costs. Moreover, the materials chosen minimize inflammatory responses and tissue irritation, facilitating seamless integration with host biology during the operational phase.
The engineering behind this system represents an intersection of materials science, optoelectronics, and biomedical engineering. The architecture leverages the semiconducting properties of silicon in thin-film, bioresorbable form, combined with circuit design optimized for minimal power consumption and maximal efficiency during NIR irradiation. These multidisciplinary innovations collectively overcome longstanding barriers in the fabrication of transient electronic implants capable of sophisticated programmable functionality.
Controlling the stimulation waveforms via light permits remote adjustment without physical connections, paving the way for real-time therapeutic modulation responsive to patient status or physiological signals. Future iterations could incorporate feedback mechanisms by integrating bioresorbable sensors that monitor tissue response, creating closed-loop systems for personalized medicine. This dynamic adaptability could be transformative in managing chronic conditions requiring variable and responsive electrical stimulation protocols.
This research also addresses one of the fundamental challenges of implantable devices: power delivery. The optical wireless power transfer circumvents the need for bulky batteries or explant procedures, offering renewed device miniaturization potential. Coupled with programmable phototransistors, these innovations enable multifunctional implants that conform to soft tissues and degrade harmlessly, a trifecta crucial for implantation in sensitive organs like the heart and nervous system.
The ability to deliver polyphasic waveforms through a single bioresorbable receiver unit is particularly noteworthy. Conventionally, generating these complex waveforms requires sophisticated circuitry and stable power sources, neither of which are trivial to implement in resorbable devices. The research showcases how optical control unlocks this capability without sacrificing bioresorbability or wireless operation, representing a paradigm shift in transient biomedical electronics.
The successful application of this device in large animal cardiac models bridges a critical gap toward clinical translation. Such models replicate human physiological scales and complexities far more closely than small animals, validating both the efficacy and safety of the system under conditions analogous to human therapies. This demonstration is an essential milestone on the path toward human clinical trials and eventual regulatory approval.
Moreover, the phrenic nerve stimulation experiments illustrate the broader applicability beyond cardiac pacing. Neuromuscular control via electrical stimulation has vast clinical relevance, from restoring motor function to modulating organ systems. The biodegradable, wireless nature of this system makes it especially suited for temporary therapeutic interventions, such as post-surgical recovery or transient disease states, where permanent implants would be unnecessary or undesirable.
While this work represents a major leap forward, ongoing challenges remain, including further optimization of device longevity relative to treatment durations, refinement of light delivery systems to maximize tissue penetration and minimize off-target effects, and integration with advanced biocompatible materials to tailor resorption timelines. Addressing these will be key to broadening the range of clinical applications and ensuring patient safety across diverse scenarios.
Overall, this wirelessly powered, light-controlled, bioresorbable stimulation system emerges as a versatile platform poised to transform bioelectronic therapies. Its elegant combination of programmable polyphasic waveform delivery, wireless operation via near-infrared light, and full bioresorbability addresses critical limitations of current implantable stimulators. By enabling sophisticated, minimally invasive, and transient electrical stimulation paradigms, this technology advances the frontiers of regenerative medicine, cardiac therapy, and neuromodulation, marking a significant milestone in the evolution of biomedical devices.
Subject of Research: Wireless bioresorbable electrical stimulation device with programmable waveform control using near-infrared light
Article Title: A wirelessly powered, light-controlled, bioresorbable stimulation system with programmable polyphasic waveforms
Article References:
Kim, J.U., Seo, S.G., Wang, H. et al. A wirelessly powered, light-controlled, bioresorbable stimulation system with programmable polyphasic waveforms. Nat Electron (2026). https://doi.org/10.1038/s41928-026-01655-8
Image Credits: AI Generated
DOI: https://doi.org/10.1038/s41928-026-01655-8

On June 16, 1963, 26-year-old Soviet cosmonaut Valentina Tereshkova made history by becoming the first woman to travel into space. A former factory seamstress, Tereshkova was an accomplished amateur parachutist with over 100 jumps — a vital skill, since Vostok cosmonauts ejected before landing. Selected from over 400 applicants in 1962, she underwent months ofContinue reading "June 16, 1963: Valentina Tereshkova is the first woman in space"
The post June 16, 1963: Valentina Tereshkova is the first woman in space appeared first on Astronomy Magazine.