Neanderthals vanished roughly 42,000 years ago, but a piece of their biology appears to be quietly at work in some people today, according to a new study led by scientists from the Max Planck Institute for Evolutionary Anthropology.
A lot of the AI work in biology has been focused on designing proteins. That's partly because proteins do most of the business of life, catalyzing the interesting chemistry and structuring cells. So, figuring out how to make a new protein can mean directly tinkering with biochemistry, providing new and potentially useful functions.
Since the genetic code provides a layer of abstraction between DNA and proteins, it wasn't obvious what a model trained on DNA could do. Yet people went ahead and made a large genome model, and it turned out to be able to output DNA sequences that could encode functional proteins in bacteria and mimic the gene structures found in complex cells. Now, those same models have been used to output the genomes of viruses that infect bacteria.
This isn't science fiction—all the viruses the models created are closely related to an existing virus. But they do have some distinct features that would be challenging to evolve. And the researchers who did the work, based at Stanford University, suggest we may want to start thinking now about preparing for the potential that someone could develop a related AI that can design a virus that targets vertebrates.
More than 150 years after Charles Darwin first wondered whether certain sticky-leaved Saxifraga plants might be secretly carnivorous, Kunming Institute of Botany researcher Tao Deng and colleagues say they have finally confirmed it.
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