PFDA, a PFAS “forever chemical,” can cause craniofacial birth defects by disrupting retinoic acid regulation during fetal development, revealing the first clear molecular mechanism behind the link. Researchers have long linked perfluoroalkyl and polyfluoroalkyl substances (PFAS), often called “forever chemicals,” to serious birth defects. However, scientists have struggled to explain exactly how these pollutants affect [...]

Scientists have uncovered an early brain mechanism that may help explain why people carrying the APOE4 gene face a higher risk of Alzheimer’s disease. For millions of people who carry the APOE4 gene, the strongest known genetic risk factor for Alzheimer’s disease, changes in brain activity may start years before memory problems become noticeable. Researchers [...]

A new study challenges the long-held idea that habits form only through slow, gradual repetition. What if your habits don’t form through countless repetitions over months or years? What if the brain can decide, almost instantly, that a behavior is no longer worth thinking about? That possibility is at the center of a new Johns [...]