A research team from the School of Biomedical Sciences at the LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has achieved a significant advance in biotechnology that could revolutionize treatment strategies for neurodegenerative diseases. The team has developed a novel tool called RNA Segment Editing (RSE), which functions like a "cut-and-patch" tool for RNA. This innovative approach allows scientists to precisely remove or replace faulty segments of genetic messages within living cells without permanently changing a person's DNA.
Cell function is determined by how DNA is expressed into proteins. That process includes two main steps—transcription, when messenger RNA (mRNA) makes copies of active genes; and translation, when mRNA guides protein assembly.