Two decades ago, scientists seemed on the verge of understanding biology in a new, quantum way. Life unfolds over an incomprehensible span of scales, from our planet-enveloping biosphere at one end, to individual cell-building biomolecules at the other. Even at its most microscopic, though, biology doesn’t really reach down to the quantum realm, in which particles act like waves…
You might imagine that the DNA in your cells has a simple history. Even though it’s been recombined in every generation through sex and gained the occasional mutation, on the whole the genome has been stable and has been passed down reliably from your ancestors. But that’s not the entire story. Nearly half of your genome is a wild drama: mobile, repetitive, disruptive, even viral.
In 2004, two mathematicians hypothesized a powerful kind of sandwich. They were studying graphs, which are collections of points (called vertices) and lines (called edges). Graphs might represent anything from social groups to the internet to neurons in the brain. The mathematicians hoped to understand properties of one type of graph — a type that’s ubiquitous in mathematics and computer science…
Quantum mechanics may be one of the most precisely tested paradigms in science, but there’s still no universally accepted interpretation of what it tells us about reality. How do we get from the wave-like behavior of quantum systems to the solid, macroscopic world of objects and the universe at large? Jonathan Halliwell, a professor of theoretical physics at Imperial College London…
Around 700 million years ago, a group of organisms resembling little more than glowing, gelatinous blobs split off from the rest of the animals, forming possibly the earliest branching animal lineage. Nearly 200 species of ctenophores, commonly known as comb jellies (but unrelated to jellyfish), live today in environments ranging from the cold depths of the sea to warm coastal surface waters.
Astronomers built the James Webb Space Telescope to pick up faint light from the first billion years after the Big Bang, a chaotic era when vast swaths of hydrogen and helium gas gathered into the chains of galaxies we see today. Even in the telescope’s first images, astronomers could see a whole zoo of mysterious smears of light. One batch of objects proved especially difficult to interpret.
For thousands and sometimes millions of years, marine plankton all over the world built their spiral shells in one direction. Then, suddenly, the spirals switched direction at the same time, everywhere, only to switch back again later. These microorganisms are types of foraminifera, or forams. Found in all oceans, from the tropics to high latitudes, they’re among the most abundant eukaryotic…
Some math problems continue to haunt researchers long after they’ve been solved. A proof emerges, is even celebrated, and yet dissatisfaction lingers. Perhaps the argument is too convoluted — the hunt persists for the elusive one-page paper — or perhaps it fails to give a deeper theoretical insight into why something is true. Whatever the reason, mathematicians return, again and again…
The mathematical universe is boundless and heterogeneous, encompassing, over here, truths about numbers and equations; there, the logic of shapes and spaces; and over there, the study of change and probability. Its domains have grown organically over centuries, each centered around its own objects, methods, and questions. That’s why it’s so surprising when direct connections between different…
On the morning of Tuesday, September 8, mathematicians at OpenAI announced that a group of 10,000 autonomous AI agents under their direction, running on an advanced model not available to the public, had found a “singularity” in the Navier-Stokes equations in three dimensions — thus resolving one of the six remaining Millennium Prize Problems posed in 2000 by the Clay Mathematics Institute…
Mathematicians are witnessing a profound shift in their field. AI systems are now producing proofs, spotting connections between distant fields, and, in a few cases, solving problems that had stumped mathematicians for decades. The pace of progress over the past several months has raised challenging questions: What can AI systems actually do? And what happens to the more human…
In July 2026, the U.S. Department of Energy selected 278 projects to fund as part of its Genesis Mission, meant to incorporate artificial intelligence into the scientific process. One project will use AI to help physicists search for a vanishingly rare particle transformation — a muon becoming an electron — by controlling different aspects of the Mu2e experiment at Fermi National Accelerator…
No larger than the head of a match, Potamopyrgus antipodarum doesn’t look very impressive. Few people visiting New Zealand’s Lake Alexandrina even notice the tiny gastropods littering the shores. The snail’s diminutive size, however, conceals a massive secret. Sometime in the recent past, its genome doubled. Instead of having two sets of chromosomes and two copies of every gene…
At the quantum scale, tiny particles behave in bizarre ways. One reason for this is the uncertainty principle, which says that the more you know about where a quantum particle is, the less you can know about how fast it’s moving, and vice versa. Recently, this rule got a rare upgrade. The new uncertainty principle relates to fractals, shapes that remain equally complex no matter how much you…
A river has my heart. It’s not the austere, black Thames winding through London, where I was born, but a lazy green one 5,000 miles away, where I spent my adolescence: the Blanco River in Texas. My maternal ancestors have dipped into its waters for generations, as I have on countless summer days. The Blanco is a tributary of the San Marcos, which flows into the Guadalupe, and on into the Gulf of…
In a laboratory 2 kilometers underground, a crane lowers Matt Depatie, a detector technologist, through a hatch into a white-walled cavern filled with about 7,000 tons of ultrapure water that glows as blue as wiper fluid in the light. “Splashdown,” Depatie says over a radio as he steps into an inflatable raft waiting below. Normally, the cavern is one of the darkest places on Earth, but today…
Pain and pleasure seem like simple facts of life, however they are anything but that. Neuroscientists still cannot say why physical pain differs from psychological pain, for instance, or why a loved one’s touch soothes while a stranger’s touch repels. To explore the science behind these sensations, Janna Levin talked to Ishmail Abdus-Saboor, a neuroscientist at Columbia University’s Zuckerman…
At first glance, corals present as little more than colorful rocks — piles of lobes, stalagmites, and branches poking out from the seafloor. They are anything but. Corals are complex creatures that form enduring colonies, and just like other animals they need oxygen to live. Across the living surface of coral, a frantic dance of survival takes place, invisible to our eyes and unknown to science…
On May 20, 2026, OpenAI made an announcement that shook the mathematical world. An internal AI model — one not available to the public — had come up with a counterexample to the “unit distance” problem, a conjecture made in 1946 by Paul Erdős, the prolific, itinerant Hungarian mathematician. Erdős posed thousands of questions, but this one was special: It was both simple to explain and…
I’ll just say it: What the hell is going on with AI “reasoning”? Sorry for the air quotes. That punctuational side-eye was more common in 2024, when the specially trained cousins of LLMs now known as “large reasoning models,” or LRMs, were still new. Nowadays it may seem downright churlish, though, given that a “general-purpose reasoning model” from OpenAI solved a famous open mathematical…
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