Biological defenses make losing weight and keeping it off unusually difficult. Better treatments, healthier environments, and sustainable habits may support long-term health more effectively than willpower alone. For years, weight loss has been framed as a simple test of discipline: consume fewer calories and exercise more. Modern research, however, shows that body weight is regulated [...]

A natural supplement strengthened lasting anticancer immune responses in obese mice. Weight loss can improve many aspects of health, but the immune system may not recover as quickly. Obesity can leave behind long-lasting changes in the bone marrow, where immune cells are formed, potentially weakening the body’s ability to respond to cancer even after excess [...]