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Experimental Copper-Based Drug Clears Alzheimer’s Plaques and Boosts Memory in Mice

Using the APP/PS1 mouse model of familial Alzheimer’s disease, Pyun et al. investigated the effect of Cu(ATSM) on brain microvascular abundance and function of P-glycoprotein and the associated effects on exogenous amyloid-beta clearance, brain amyloid burden, and cognitive function. Image credit: Pyun et al., doi: 10.1021/acschemneuro.6c00252.

Copper diacetyl bis(4-methyl-3-thiosemicarbazone), or Cu(ATSM), restored a key waste-removal system in the brain, reducing toxic amyloid-beta buildup and improving spatial memory in lab models of Alzheimer’s disease, according to a team of researchers at Monash University.

The post Experimental Copper-Based Drug Clears Alzheimer’s Plaques and Boosts Memory in Mice appeared first on Sci.News: Breaking Science News.

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Follow the Money: Pandemic Fearmongering is a Growth Industry

From Ebola to Nipah, the combined death toll since Covid is under 1,000 worldwide. So why the endless panic? Follow the money – pandemic fearmongering is a growth industry, says Dr David Bell.

The post Follow the Money: Pandemic Fearmongering is a Growth Industry appeared first on The Daily Sceptic.

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Joint Pain Supplement Linke to Faster Alzheimer’s Growth

Glucosamine has become one of the world’s most popular dietary supplements. Many people take it daily to ease joint discomfort, maintain cartilage health, and remain active as they grow older. Because it has been available for years and is widely sold without a prescription, glucosamine is often viewed as a harmless addition to a healthy […]

The post Joint Pain Supplement Linke to Faster Alzheimer’s Growth appeared first on Knowridge Science Report.

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New Drug Could Slow the Development of Alzheimer’s

Alzheimer’s disease is one of the greatest medical challenges of our time. Millions of people around the world live with the condition, and the number continues to grow as populations age. The disease slowly destroys memory, thinking abilities, and independence. Although several drugs have been developed in recent years, most only slow the disease for […]

The post New Drug Could Slow the Development of Alzheimer’s appeared first on Knowridge Science Report.

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Could Alzheimer’s Disease Start With Mutated Immune Cells? New Research Reveals an Unexpected Clue

For many years, scientists have searched for the causes of Alzheimer’s disease. Most attention has focused on abnormal protein deposits that build up inside the brain. These protein clumps are considered one of the main signs of the disease. However, a new study suggests that another process may also be involved, and it comes from […]

The post Could Alzheimer’s Disease Start With Mutated Immune Cells? New Research Reveals an Unexpected Clue appeared first on Knowridge Science Report.

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