Biomedical tests using augmented and virtual reality tools to advance space health dominated the research schedule aboard the International Space Station on Wednesday. The Expedition 74 crew is also turning its attention to a spacewalk at the end of the month following the departure of a U.S. cargo spacecraft.

NASA flight engineers Jessica Meir and Jack Hathaway began their shift in the Columbus laboratory module conducting vein scans with guidance from doctors on the ground. The duo took turns scanning each other with the EchoFinder-2 ultrasound device that collects health data using augmented reality and artificial intelligence tools. The medical hardware provided by ESA (European Space Agency) provides a screen using augmented reality to guide the operator’s probe motion and artificial intelligence software to detect the subject’s organs. The lightweight, easy-to-use gear may enable independent crew health monitoring on spacecraft travelling to the Moon, Mars, and beyond.

Afterward, Hathaway moved to the Harmony module and loaded bacteria samples into a portable DNA sequencer to read their genetic code. Scientists will use the knowledge to understand bacterial resistance to antibiotics in the space environment potentially affecting an astronaut’s ability to fight an infection.  

Meir assisted NASA flight engineer Chris Williams who wore virtual reality goggles for a test measuring his ability to detect balance, movement, orientation in microgravity. The goggles recorded Williams’s eye movements as he responded to visual stimuli generated by computer software operated by Meir. The vestibular system investigation, just one part of the CIPHER suite of 14 human research experiments, is studying how astronauts neurologically adapt to weightlessness to improve crew training and safety.

ESA flight engineer Sophie Adenot helped her crewmates with the digital health science on Wednesday first setting up the EchoFinder-2 hardware, connecting it to a computer tablet, and installing a camera to track the vein study. Next, Adenot configured Harmony’s maintenance work area and retrieved a mini-cold bag to house the bacteria samples for the antibiotics study. Finally, she took pictures of the Moon to observe Earth’s light reflecting off the lunar surface.

All four astronauts gathered together at the end of their shift for a conference call with spacewalk experts on the ground. The quartet and the engineers discussed the tools and procedures necessary to repair a wrist joint on the Canadarm2 robotic arm during a spacewalk planned for June 30. NASA will soon announce the spacewalkers and provide a live televised briefing for more details before the end of the month.

Roscosmos flight engineer Andrey Fedyaev conducted another neurological study while wearing a virtual reality headset and responded to computerized stimuli as electrodes measured brain activity and tracked eye movement, testing his sense of direction, movement, and position. Station commander Sergey Kud-Sverchkov and flight engineer Sergei Mikaev, both from Roscosmos, started their shift in the Nauka science module checking the operation of components supporting the Elektron oxygen generator. Kud-Sverchkov then tested communications gear inside the Soyuz MS-28 crew spacecraft. Mikaev took a computer quiz documenting his mental state before terminating a 24-hour heart and blood pressure monitoring session.

A SpaceX Dragon cargo spacecraft is back on Earth following its undocking from the orbital outpost on Tuesday and splashdown in the Pacific Ocean at 5:11 a.m. PDT/8:11 a.m. EDT on Wednesday. Dragon returned sensitive scientific samples from investigations studying stem cell manufacturing, cartilage tissue printing, and more to treat a range of conditions from blood diseases, cancers, and cartilage injuries.

Learn more about station activities by following the space station blog, @space_stationon X, as well as the ISS Facebook and ISS Instagram accounts.

Get the latest from NASA delivered every week. Subscribe here.

The post Advanced Health Research on Station Using Augmented, Virtual Reality Tools appeared first on NASA Science.

At 5:11 a.m. PDT (8:11 a.m. EDT), the unpiloted SpaceX Dragon spacecraft splashed down off the coast of California near Oceanside, marking the return of the 34th SpaceX commercial resupply services mission to the International Space Station for NASA.

Dragon undocked at 12:25 p.m. EDT on June 16, carrying samples that could shape future space exploration and life on Earth.  Research returning includes bioprinted organ and cartilage tissue, data on improving cryogenic fuel storage for future space missions, and DNA‑inspired materials to develop new cancer treatments. The returning hardware includes an ocular imaging device used to monitor crew members’ eye health, an absorbent bed that filters trace contaminants from cabin air, and a separator pump from the waste and hygiene compartment.

The spacecraft arrived at the space station on May 17 after launching two days earlier on a Falcon 9 rocket from Space Launch Complex 40 at Cape Canaveral Space Force Station in Florida.

Learn more about station activities by following the space station blog, @space_station on X, as well as the ISS Facebook and ISS Instagram accounts.

Get the latest from NASA delivered every week. Subscribe here.

The post SpaceX Dragon Splashes Down in Pacific, Completes Cargo Mission appeared first on NASA Science.

Astronauts aboard the International Space Station have switched on NASA’s newly upgraded Cold Atom Lab, a one-of-a-kind facility designed to improve how scientists explore the fundamental workings of matter and develop new quantum technologies. By leveraging the unique environment of microgravity in space, the lab can accomplish cutting-edge science impossible to do anywhere else.

Quantum science is the study of matter at the smallest scales, like atoms, electrons, and single particles of light. While it’s easy to imagine atoms as billiard balls bouncing off one another, they also exhibit wave-like behavior, can exist simultaneously in two places at once, and may even pass through one another.

About the size of a minifridge and operated from Earth, the Cold Atom Lab chills atoms to temperatures below minus 459 degrees Fahrenheit (minus 237 degrees Celsius). At this extreme cold, just above absolute zero, atoms form a large quantum object called a Bose‑Einstein condensate, or BEC, a collection of matter waves that is a fifth state of matter beyond solids, liquids, gases, and plasma. This object follows the rules of quantum mechanics despite being much larger than subatomic particles, and the microgravity of low Earth orbit helps make the waves even larger.

“At the coldest temperatures, matter behaves drastically different from anything we have experienced,” said Jason Williams, project scientist for Cold Atom Lab at NASA’s Jet Propulsion Laboratory in Southern California, which built the facility. “The wavelike nature of matter dominates, and ultracold matter can behave in ways that are not only unexpected, but that also enable extremely precise measurements of time, gravity, and motion. The lab has lots of tools — especially with this latest upgrade — to let us probe the nature of the universe.”

The project supports five international teams studying fundamental physics. It also tests the space-readiness of quantum tools that could support future Earth science and space exploration missions.

How it works

The heart of the Cold Atom Lab is a complex set of instruments called its science module. An upgraded module launched on April 11 as part of a Commercial Resupply Services mission to the space station, enabling new kinds of experiments.

For each experiment, a strip of rubidium or potassium metal is heated to as high as 750 F (400 C) — hot enough to form a gas within the facility’s vacuum chamber. Lasers tuned to specific frequencies are then fired at the gas, draining the energy from these atoms, and cooling them by slowing them down. Once this gas has completed the laser-cooling stage, a magnetic trap captures and holds the gas in place. Through a series of complex techniques, the laboratory reduces an atom cloud’s energy further, bringing it close to a standstill and maximizing its time in microgravity.

While facilities for studying ultracold gases exist on Earth, the Cold Atom Lab can study quantum gases in microgravity for longer periods of time and at even lower temperatures. Conducting these experiments in low gravity allows scientists to study larger quantum waves that also interact for longer times with gravity. To harness these benefits, the Cold Atom Lab essentially shrinks an atom physics lab, typically the size of an entire room filled with lasers and tabletop mirrors, to fit within an experiment rack aboard the space station.

“As the first project to create Bose-Einstein condensates in orbit, we’re demonstrating that we can make quantum technology work reliably in space,” said Ethan Elliott, deputy project scientist for Cold Atom Lab at JPL. “In the previous century, there was a quantum revolution that led to lasers, cellphones, and MRIs for medical imaging. We’re performing quantum 2.0 — direct manipulation of large quantum states — and we hope for similar gains in quantum tech by advancing this science in orbit.”

The latest upgrade is the fourth since the Cold Atom Lab arrived at the space station in 2018. Key improvements include a newly designed magnetic trap that changes the shape of the quantum gas clouds, allowing scientists to test different properties related to their atoms. The upgrade also features redesigned metal strips that act as sources for those gas clouds.

“It’s the closest thing we have to controlling the boundary of the quantum world,” said Kamal Oudrhiri, project manager of Cold Atom Lab at JPL, referring to those low temperatures. “This new upgrade pushes that boundary even further.”

The upgrade, Oudrhiri added, “demonstrates NASA’s ability to maintain U.S. leadership in space-based quantum technologies while maturing future quantum instruments, such as matter-wave interferometers for fundamental physics missions, positioning, navigation, timing, and gravity sensing of Earth, the Moon, and beyond.”

More about Cold Atom Lab

Managed by Caltech in Pasadena, JPL designed, built, and operates the Cold Atom Lab, which is sponsored by the Biological and Physical Sciences division of NASA’s Science Mission Directorate at the agency’s headquarters in Washington. The division pioneers scientific discovery and enables exploration by using space environments to conduct investigations that are not possible on Earth. Studying biological and physical phenomena under extreme conditions allows researchers to advance the fundamental scientific knowledge required to go farther and stay longer in space, while also benefiting life on Earth. 

To learn more about Cold Atom Lab, visit:

https://nasa.gov/cold-atom-laboratory/

Media Contact

Andrew Good
Jet Propulsion Laboratory, Pasadena, Calif.
818-393-2433
andrew.c.good@jpl.nasa.gov

2026-039

The post NASA’s Quantum Lab Aboard Space Station Gets Chilly Upgrade appeared first on NASA Science.

Astronauts aboard the International Space Station have switched on NASA’s newly upgraded Cold Atom Lab, a one-of-a-kind facility designed to improve how scientists explore the fundamental workings of matter and develop new quantum technologies. By leveraging the unique environment of microgravity in space, the lab can accomplish cutting-edge science impossible to do anywhere else.

Quantum science is the study of matter at the smallest scales, like atoms, electrons, and single particles of light. While it’s easy to imagine atoms as billiard balls bouncing off one another, they also exhibit wave-like behavior, can exist simultaneously in two places at once, and may even pass through one another.

About the size of a minifridge and operated from Earth, the Cold Atom Lab chills atoms to temperatures below minus 459 degrees Fahrenheit (minus 237 degrees Celsius). At this extreme cold, just above absolute zero, atoms form a large quantum object called a Bose‑Einstein condensate, or BEC, a collection of matter waves that is a fifth state of matter beyond solids, liquids, gases, and plasma. This object follows the rules of quantum mechanics despite being much larger than subatomic particles, and the microgravity of low Earth orbit helps make the waves even larger.

“At the coldest temperatures, matter behaves drastically different from anything we have experienced,” said Jason Williams, project scientist for Cold Atom Lab at NASA’s Jet Propulsion Laboratory in Southern California, which built the facility. “The wavelike nature of matter dominates, and ultracold matter can behave in ways that are not only unexpected, but that also enable extremely precise measurements of time, gravity, and motion. The lab has lots of tools — especially with this latest upgrade — to let us probe the nature of the universe.”

The project supports five international teams studying fundamental physics. It also tests the space-readiness of quantum tools that could support future Earth science and space exploration missions.

How it works

The heart of the Cold Atom Lab is a complex set of instruments called its science module. An upgraded module launched on April 11 as part of a Commercial Resupply Services mission to the space station, enabling new kinds of experiments.

For each experiment, a strip of rubidium or potassium metal is heated to as high as 750 F (400 C) — hot enough to form a gas within the facility’s vacuum chamber. Lasers tuned to specific frequencies are then fired at the gas, draining the energy from these atoms, and cooling them by slowing them down. Once this gas has completed the laser-cooling stage, a magnetic trap captures and holds the gas in place. Through a series of complex techniques, the laboratory reduces an atom cloud’s energy further, bringing it close to a standstill and maximizing its time in microgravity.

While facilities for studying ultracold gases exist on Earth, the Cold Atom Lab can study quantum gases in microgravity for longer periods of time and at even lower temperatures. Conducting these experiments in low gravity allows scientists to study larger quantum waves that also interact for longer times with gravity. To harness these benefits, the Cold Atom Lab essentially shrinks an atom physics lab, typically the size of an entire room filled with lasers and tabletop mirrors, to fit within an experiment rack aboard the space station.

“As the first project to create Bose-Einstein condensates in orbit, we’re demonstrating that we can make quantum technology work reliably in space,” said Ethan Elliott, deputy project scientist for Cold Atom Lab at JPL. “In the previous century, there was a quantum revolution that led to lasers, cellphones, and MRIs for medical imaging. We’re performing quantum 2.0 — direct manipulation of large quantum states — and we hope for similar gains in quantum tech by advancing this science in orbit.”

The latest upgrade is the fourth since the Cold Atom Lab arrived at the space station in 2018. Key improvements include a newly designed magnetic trap that changes the shape of the quantum gas clouds, allowing scientists to test different properties related to their atoms. The upgrade also features redesigned metal strips that act as sources for those gas clouds.

“It’s the closest thing we have to controlling the boundary of the quantum world,” said Kamal Oudrhiri, project manager of Cold Atom Lab at JPL, referring to those low temperatures. “This new upgrade pushes that boundary even further.”

The upgrade, Oudrhiri added, “demonstrates NASA’s ability to maintain U.S. leadership in space-based quantum technologies while maturing future quantum instruments, such as matter-wave interferometers for fundamental physics missions, positioning, navigation, timing, and gravity sensing of Earth, the Moon, and beyond.”

More about Cold Atom Lab

Managed by Caltech in Pasadena, JPL designed, built, and operates the Cold Atom Lab, which is sponsored by the Biological and Physical Sciences division of NASA’s Science Mission Directorate at the agency’s headquarters in Washington. The division pioneers scientific discovery and enables exploration by using space environments to conduct investigations that are not possible on Earth. Studying biological and physical phenomena under extreme conditions allows researchers to advance the fundamental scientific knowledge required to go farther and stay longer in space, while also benefiting life on Earth. 

To learn more about Cold Atom Lab, visit:

https://nasa.gov/cold-atom-laboratory/

Media Contact

Andrew Good
Jet Propulsion Laboratory, Pasadena, Calif.
818-393-2433
andrew.c.good@jpl.nasa.gov

2026-039

At 12:25 p.m. EDT, the unpiloted SpaceX Dragon spacecraft undocked from the forward‑facing port of the International Space Station’s Harmony module after a command from SpaceX ground controllers. Flight controllers delayed the undocking slightly to power‑cycle a navigation sensor and restore full redundancy before departure.

Dragon will reenter Earth’s atmosphere on Wednesday, June 17, before splashing down off the coast of California at approximately 5:08 a.m. PDT. NASA will not stream the splashdown but will post updates on its space station blog.

Learn more about station activities by following the space station blog, @space_stationon X, as well as the ISS Facebook and ISS Instagram accounts.

Get the latest from NASA delivered every week. Subscribe here.

The post Dragon Undocks to Return Science Experiments to Earth appeared first on NASA Science.

NASA’s live coverage of the undocking and departure of 34th SpaceX commercial resupply services mission to the International Space Station for NASA is underway on NASA+, Amazon Prime, and the agency’s YouTube channel. Learn how to watch NASA content through a variety of online platforms, including social media.

The unpiloted SpaceX Dragon spacecraft will undock at approximately 12:05 p.m. EDT from the forward-facing port of the station’s Harmony module and fire its thrusters to move safely away from the orbital complex.

On Wednesday, June 17, Dragon will reenter Earth’s atmosphere before splashing down off the coast of California at approximately 5:08 a.m. PDT. NASA will not stream the splashdown but will post updates on its space station blog. 

Dragon will return to Earth with thousands of pounds of cargo in one of the most research-packed returns in commercial resupply mission history, carrying samples that could shape future space exploration and life on Earth. Research returning on this mission includes bioprinted organ and cartilage tissue, data on improving cryogenic fuel storage for future space missions, and DNA‑inspired materials to develop new cancer treatments. The returning hardware includes an ocular imaging device used to monitor crew members’ eye health, a sorbent bed that filters trace contaminants from cabin air, and a separator pump from the waste and hygiene compartment.  

Loaded with nearly 6,500 pounds of crew cargo and science experiments, Dragon arrived at the station on May 17 after launching two days earlier on a Falcon 9 rocket from Space Launch Complex 40 at Cape Canaveral Space Force Station in Florida. 

Learn more about station activities by following the space station blog, @space_stationon X, as well as the ISS Facebook and ISS Instagram accounts.

Get the latest from NASA delivered every week. Subscribe here.

The post SpaceX Dragon Prepares for Undocking and Return to Earth appeared first on NASA Science.

Scientists await a big splash in the Pacific Ocean as one of the most research-packed Dragon spacecraft to date returns, completing the 34th SpaceX commercial resupply mission to the International Space Station for NASA. Biological and materials samples, along with tested hardware, are heading back to research teams on Earth for further analysis, advancing NASA’s work to prepare humans for exploration beyond low Earth orbit and to deliver benefits back home.

Tiny cells, huge health insights

Some samples returning are for NASA’s Hematopoietic Stem Cell Expansion in Space: Pathfinder Investigation (InSPA-StemCellEX-H2), which seeks to use the microgravity environment to scale up the production of stems cells. On Earth, lab-produced blood stem cells lose their ability to form different cell types, like red and white blood cells that are critical to treating patients with certain blood diseases and cancers. In microgravity, researchers believe this ability will be better preserved while also growing these stem cells in greater numbers. The returning samples will undergo further analysis to determine if space-based efforts produce larger quantities of enhanced stem cells suitable for clinical use.

The team behind NASA’s Streptococcus pneumoniae (Spn) Infection of Cardiac Tissue (MVP Cell-09) experiment is awaiting the return of stem cell-derived heart tissues that were intentionally infected with a pneumonia-causing bacterium as part of ongoing microgravity research. Pneumonia increases the risk of heart disease, which is not fully understood. Because bacteria tend to become more active and virulent in microgravity, this experiment could amplify their effects, making it possible to detect cellular responses that cannot be observed on Earth.

NASA’s Megakaryocyte Flying-One (MeF1) samples are returning to Earth to help understand how large cells found in bone marrow, known as megakaryocytes, and the platelets they produce adapt to spaceflight. Megakaryocytes and platelets play important roles in the formation of blood clots and immune responses. The returning samples, including those taken from astronauts, could show us how the human immune system reacts aboard the space station and help prepare for future exploration missions.

Driving design enhancements

Many spacecraft use cryogenic fuels for propulsion, but temperature swings in space can cause these extremely cold fuels to slowly evaporate and escape their tank, reducing fuel efficiency and complicating mission planning. NASA’s Zero Boil-Off Tank Noncondensables (ZBOT-NC) investigation aboard station studies how gases that do not condense into liquids at cold temperatures affect pressure control and fluid behaviors in propellant tanks. Hardware returning aboard Dragon, including drives containing fluid-physics data, could help validate models and contribute to the design of more efficient cryogenic fuel storage systems for long-duration missions.

Semiconductor research samples as part of NASA’s In-Space Production of Semimetal-Semiconductor Composite Bulk Crystals in Microgravity (SUBSA-InSPA-SSCug) investigation are returning to Earth for further analysis. This study manufactured semimetal-semiconductor composite alloy crystals in space, which have applications in many electronics, including sensors and lasers. Researchers believe microgravity could enable the production of significantly greater and higher-quality crystals, supporting the development of next-generation semiconductor technologies.

Innovative medical research mix

NASA’s DNA Nano Therapeutics-3 research team will receive tiny, space-assembled DNA-inspired materials that are combined with medicines to create active cancer treatments. Producing these treatments in microgravity can improve how well they perform in the body. This research could improve patient outcomes by helping therapies reach tumors more effectively, stay in the body longer, and improve medicine release.

Tissue models of the brain, heart, liver, and kidney that were tested with novel RNA-based medicines as part of NASA’s InSPA-Sachi Nanoligomer investigation are also returning. Microgravity can accelerate aging and disease processes, giving researchers a unique environment to better observe how well these new drugs work on different organs ahead of clinical trials.

Samples from ESA’s (European Space Agency) Green Bone investigation are returning to Earth to help understand how bone cells grow and develop on a new scaffold made from wood. Designed to mimic real bone, this scaffold was tested in microgravity to understand its ability to heal defects and fractures. Because living in microgravity simulates conditions like osteoporosis, a skeletal disorder which affects millions of people worldwide, the results could help treat patients with these fragile bone conditions. 

NASA’s 3D Bone Marrow Analog research team will analyze the returning 3D-printed tissues that mimic parts of the bone marrow. Spaceflight can cause aging-like changes, including bone and muscle loss. To investigate potential countermeasures, these tissue models were exposed to small vibrations aboard the space station to simulate exercise. After the samples return to Earth, researchers will measure bone-like mineral formations and observe cellular and genetic changes. Findings from this investigation could help develop new strategies to maintain astronaut bone and muscle health during future long-duration missions.

In the United States, more than 900,000 knee cartilage injuries occur annually, with many requiring surgery. NASA’s InSPA-Auxilium Bioprinter-Cell Printing is investigating how to treat these injuries and is returning 3D-printed cartilage tissue samples from space station. This investigation uses the orbiting laboratory’s unique microgravity environment to bioprint cartilage tissues with more evenly distributed cells compared to those printed on Earth. The results could help produce higher-quality cartilage prints to treat joint injuries.

The post NASA’s SpaceX CRS-34 Dragon Returns Packed with Space Station Science appeared first on NASA Science.

Scientists await a big splash in the Pacific Ocean as one of the most research-packed Dragon spacecraft to date returns, completing the 34th SpaceX commercial resupply mission to the International Space Station for NASA. Biological and materials samples, along with tested hardware, are heading back to research teams on Earth for further analysis, advancing NASA’s work to prepare humans for exploration beyond low Earth orbit and to deliver benefits back home.

Tiny cells, huge health insights

Some samples returning are for NASA’s Hematopoietic Stem Cell Expansion in Space: Pathfinder Investigation (InSPA-StemCellEX-H2), which seeks to use the microgravity environment to scale up the production of stems cells. On Earth, lab-produced blood stem cells lose their ability to form different cell types, like red and white blood cells that are critical to treating patients with certain blood diseases and cancers. In microgravity, researchers believe this ability will be better preserved while also growing these stem cells in greater numbers. The returning samples will undergo further analysis to determine if space-based efforts produce larger quantities of enhanced stem cells suitable for clinical use.

The team behind NASA’s Streptococcus pneumoniae (Spn) Infection of Cardiac Tissue (MVP Cell-09) experiment is awaiting the return of stem cell-derived heart tissues that were intentionally infected with a pneumonia-causing bacterium as part of ongoing microgravity research. Pneumonia increases the risk of heart disease, which is not fully understood. Because bacteria tend to become more active and virulent in microgravity, this experiment could amplify their effects, making it possible to detect cellular responses that cannot be observed on Earth.

NASA’s Megakaryocyte Flying-One (MeF1) samples are returning to Earth to help understand how large cells found in bone marrow, known as megakaryocytes, and the platelets they produce adapt to spaceflight. Megakaryocytes and platelets play important roles in the formation of blood clots and immune responses. The returning samples, including those taken from astronauts, could show us how the human immune system reacts aboard the space station and help prepare for future exploration missions.

Driving design enhancements

Many spacecraft use cryogenic fuels for propulsion, but temperature swings in space can cause these extremely cold fuels to slowly evaporate and escape their tank, reducing fuel efficiency and complicating mission planning. NASA’s Zero Boil-Off Tank Noncondensables (ZBOT-NC) investigation aboard station studies how gases that do not condense into liquids at cold temperatures affect pressure control and fluid behaviors in propellant tanks. Hardware returning aboard Dragon, including drives containing fluid-physics data, could help validate models and contribute to the design of more efficient cryogenic fuel storage systems for long-duration missions.

Semiconductor research samples as part of NASA’s In-Space Production of Semimetal-Semiconductor Composite Bulk Crystals in Microgravity (SUBSA-InSPA-SSCug) investigation are returning to Earth for further analysis. This study manufactured semimetal-semiconductor composite alloy crystals in space, which have applications in many electronics, including sensors and lasers. Researchers believe microgravity could enable the production of significantly greater and higher-quality crystals, supporting the development of next-generation semiconductor technologies.

Innovative medical research mix

NASA’s DNA Nano Therapeutics-3 research team will receive tiny, space-assembled DNA-inspired materials that are combined with medicines to create active cancer treatments. Producing these treatments in microgravity can improve how well they perform in the body. This research could improve patient outcomes by helping therapies reach tumors more effectively, stay in the body longer, and improve medicine release.

Tissue models of the brain, heart, liver, and kidney that were tested with novel RNA-based medicines as part of NASA’s InSPA-Sachi Nanoligomer investigation are also returning. Microgravity can accelerate aging and disease processes, giving researchers a unique environment to better observe how well these new drugs work on different organs ahead of clinical trials.

Samples from ESA’s (European Space Agency) Green Bone investigation are returning to Earth to help understand how bone cells grow and develop on a new scaffold made from wood. Designed to mimic real bone, this scaffold was tested in microgravity to understand its ability to heal defects and fractures. Because living in microgravity simulates conditions like osteoporosis, a skeletal disorder which affects millions of people worldwide, the results could help treat patients with these fragile bone conditions. 

NASA’s 3D Bone Marrow Analog research team will analyze the returning 3D-printed tissues that mimic parts of the bone marrow. Spaceflight can cause aging-like changes, including bone and muscle loss. To investigate potential countermeasures, these tissue models were exposed to small vibrations aboard the space station to simulate exercise. After the samples return to Earth, researchers will measure bone-like mineral formations and observe cellular and genetic changes. Findings from this investigation could help develop new strategies to maintain astronaut bone and muscle health during future long-duration missions.

In the United States, more than 900,000 knee cartilage injuries occur annually, with many requiring surgery. NASA’s InSPA-Auxilium Bioprinter-Cell Printing is investigating how to treat these injuries and is returning 3D-printed cartilage tissue samples from space station. This investigation uses the orbiting laboratory’s unique microgravity environment to bioprint cartilage tissues with more evenly distributed cells compared to those printed on Earth. The results could help produce higher-quality cartilage prints to treat joint injuries.

The Expedition 74 crew members packed a SpaceX Dragon cargo spacecraft on Monday with sensitive science experiments and lab hardware for return to Earth. The orbital residents also configured spacewalking tools and conducted cardiac research to kick off the week aboard the International Space Station.

A SpaceX Dragon cargo spacecraft is scheduled to undock from the Harmony module’s forward port at 12:05 p.m. EDT on Tuesday ending its stay at the orbital laboratory that began on April 17. NASA+ will begin its broadcast of Dragon’s undocking and departure at 11:45 a.m. Dragon’s parachute-assisted splashdown in the Pacific Ocean off the coast of southern California the following day will not be televised.

The astronauts are partnering together transferring portable science freezers loaded with critical research samples and packing lab equipment into Dragon following a month of intense research into a variety of space-designed therapies to protect human health. The freezers house the results of investigations into stem cell manufacturing, cartilage tissue printing, and more to treat a range of conditions from blood diseases, cancers, and cartilage injuries. Doctors on the ground will analyze the preserved samples to gain advanced health insights unobtainable in Earth’s gravity environment.

NASA flight engineers Chris Williams and Jack Hathaway started the cargo work early Monday packing and securing station hardware inside Dragon for the ride back to Earth. Next, flight engineer Sophie Adenot of ESA (European Space Agency) installed the sample-packed freezers in Dragon where they will stay powered on preserving the biomedical specimens for retrieval on the ground. Finally, NASA flight engineer Jessica Meir capped off Monday’s shift with more scientific transfers then cleaned and inspected hatch seals on Harmony’s port where Dragon is docked.

Meanwhile, preparations continue for a spacewalk planned for June 30 to replace a wrist joint on the Canadarm2 robotic arm. Adenot began her shift in the Quest airlock charging lithium-ion batteries that power spacesuit gloves, helmet cameras, and pistol grip tools. Williams and Meir joined each other during a break in their Dragon packing and inspected tethers that secure astronauts to the orbiting lab during spacewalks.

Station commander Sergey Kud-Sverchkov and flight engineer Sergei Mikaev, both from Roscosmos, took turns wearing a series of arm, wrist, and finger cuffs measuring how living in space affects their blood pressure. Next, Kud-Sverchkov attached electrocardiogram sensors to his chest that will monitor his cardiac activity for 24 hours. Mikaev turned his attention to Earth observations, pointed a camera out a station window, and photographed landmarks across the Pacific Ocean including islands and volcanos.

Flight engineer Andrey Fedyaev began his shift transferring fluids and disinfecting tanks throughout the station’s Roscosmos segment. Fedyaev wrapped up his shift working on ventilation system maintenance and checking station lighting conditions and illumination levels.

Learn more about station activities by following the space station blog, @space_stationon X, as well as the ISS Facebook and ISS Instagram accounts.

Get the latest from NASA delivered every week. Subscribe here.

The post Crew Packs Dragon for Tuesday Departure and Preps for Spacewalk appeared first on NASA Science.

Space agriculture, stem cells, and cargo operations wrapped up the week aboard the International Space Station. The Expedition 74 crew also conducted blood tests and installed a new food processor as a U.S. cargo spacecraft nears the end of its mission.

Launching a spacecraft on Earth packed with enough food for a yearslong crew mission or sending resupply ships to replenish a crew beyond low Earth orbit is prohibitive. Therefore, growing plants aboard a spacecraft is key to sustaining crews on long-duration missions to the Moon, Mars, and beyond. As a result, NASA and its international partners have been exploring growing crops in space to enable crews to feed themselves without support from Earth. NASA flight engineer Chris Williams contributed to the ongoing space agriculture research at the end of the week and configured a microscope to observe plant cell division in microgravity. Insights may lead to improved methods of growing food in space as well as on lunar and planetary surfaces.

Low Earth orbit may also be the next frontier for biomedical manufacturing as doctors seek to overcome the limitations of gravity on the ground. NASA flight engineer Jessica Meir harvested blood stem cells inside the Kibo laboratory module’s Life Science Glovebox (LSG) that have been growing aboard the orbital outpost since the arrival of a SpaceX Dragon cargo craft on May 17. Next, she looked at the density and viability of the live cells using the KERMIT fluorescent microscope. Researchers are exploring space-designed cell therapies to treat serious medical conditions such as blood cancers and immune diseases.

Dragon is due to depart the International Space Station at 12:05 p.m. EDT on Tuesday, June 16, to return the stem cell samples, including several tons of completed science experiments and lab hardware, for analysis on Earth. Live coverage of Dragon’s undocking and departure begins at 11:45 a.m. on NASA+.

Williams and Meir also partnered with flight engineers Jack Hathaway of NASA and Sophie Adenot of ESA (European Space Agency) packing Dragon with return cargo together throughout Friday. The quartet will intensify their cargo transfers early next week when they begin loading Dragon with sensitive research samples packed inside portable science freezers for preservation, retrieval, and analysis on Earth.

Williams and Meir began their Friday shift collecting blood samples for spinning in a centrifuge then stowing in a science freezer for future analysis. Hathaway removed a research freezer from inside Kibo’s Life Science Glovebox used the day before to preserve bacteria samples for genetic and chemical analysis. Adenot also spent some time assisting Meir during the stem cell operations then tested a new food processor in the Columbus laboratory module by cooking a Mediterranean dish.

The station’s three cosmonauts, station commander Sergey Kud-Sverchkov and flight engineers Sergei Mikaev and Andrey Fedyaev enjoyed an off-duty day on Friday.

Learn more about station activities by following the space station blog, @space_stationon X, as well as the ISS Facebook and ISS Instagram accounts.

Get the latest from NASA delivered every week. Subscribe here.

The post Botany and Biology Research Wrap Up Week as Dragon Preps for Earth Return appeared first on NASA Science.

Microbiology dominated the research schedule aboard the International Space Station on Thursday helping doctors protect health on Earth and in space. The Expedition 74 crew also tested a new spacesuit, packed a U.S. cargo spacecraft, and kept up lab maintenance throughout the orbital outpost.

Scientists are comparing bacteria samples grown onboard the orbiting lab to similar samples living in simulated microgravity chambers on Earth to learn how microbes respond to space-like conditions. ESA (European Space Agency) astronaut Sophie Adenot kicked off the Odyssey biotechnology investigation processing microbe samples inside the Kibo laboratory module’s Life Science Glovebox (LSG) to document their genetic function. Next, NASA flight engineer Chris Williams collected the microbes for preservation and cleaned the research hardware inside the LSG for continuing operations. Finally, NASA flight engineer Jessica Meir took over and completed the day’s genetic study treating the sensitive samples to observe their chemical response. She immediately stowed the microbes for preservation afterward inside the LSG’s science freezer that she had installed the day before. Insights gained from the new study may lead to new ways of protecting humans and equipment exposed to harsh conditions on and off the Earth.

After completing her microbe work, Adenot moved to the Columbus laboratory module and tried on a prototype spacesuit designed by ESA to be worn inside a spacecraft. She tested the EuroSuit for its ease of donning on and off, as well as its comfort and mobility, then documented her experience for engineers to review. Results will inform the final design of the suit to meet the ergonomic requirements of living and working in space.

Williams also continued packing cargo inside a SpaceX Dragon cargo spacecraft with assistance from NASA flight engineer Jack Hathaway. Dragon is being loaded with several thousand pounds of station gear and science experiments that will be returned to Earth for analysis by engineers and scientists. Hathaway spent the majority of his shift inside the Tranquility module swapping orbital plumbing components and transferring water between tanks for life support maintenance.

Meir began her shift servicing fluid-containing sample processing hardware that is supporting the observation of pharmaceutical crystal growth to promote the production of advanced cancer therapies in weightlessness. Next, she activated tubes filled with microbial and botanical samples for a variety of student-designed experiments inside the Harmony module.

Roscosmos cosmonaut and station commander Sergey Kud-Sverchkov inspected and cleaned ventilation equipment then repaired a thermal sensor inside the Zvezda service module. Flight engineer Sergei Mikaev disinfected surfaces inside the Zarya module and checked the functionality of video hardware. Flight engineer Andrey Mikaev spent his shift on orbital plumbing and oxygen generator maintenance in the space station’s Roscosmos segment.

Learn more about station activities by following the space station blog, @space_stationon X, as well as the ISS Facebook and ISS Instagram accounts.

Get the latest from NASA delivered every week. Subscribe here.

The post Microbiology DNA and Chemistry for Health Insights Tops Research Schedule appeared first on NASA Science.

A soccer ball floats in microgravity in this March 2, 2026, picture from the International Space Station. The space station crew tested soccer balls to study how internal mass affects motion and stability in microgravity. The findings have improved understanding of how embedded technologies, including match-ball sensors, can influence performance during play.

Through research aboard the International Space Station and technology developed for exploration, NASA continues to demonstrate how discoveries made for space can benefit people on Earth—including athletes and fans participating in the world’s most popular sport.

Image credit: NASA

The post Soccer Meets Space Science appeared first on NASA Science.

A soccer ball floats in microgravity in this March 2, 2026, picture from the International Space Station. The space station crew tested soccer balls to study how internal mass affects motion and stability in microgravity. The findings have improved understanding of how embedded technologies, including match-ball sensors, can influence performance during play.

Through research aboard the International Space Station and technology developed for exploration, NASA continues to demonstrate how discoveries made for space can benefit people on Earth—including athletes and fans participating in the world’s most popular sport.

Image credit: NASA

Scientific hardware installations and biomedical monitoring topped the research schedule aboard the International Space Station on Wednesday. The Expedition 74 crew members also adjusted a spacesuit to prepare for a spacewalk and explored space physics to round out their day.

A series of shoebox-sized CubeSats will soon be deployed outside the Kibo laboratory module into Earth orbit for public and private research. One of the satellites, Hokushin-1 CubeSat, will test space technologies such as radio frequency, propulsion, and solar arrays. NASA flight engineer Jack Hathaway finished installing a small satellite orbital deployer, packed with the CubeSats, into Kibo’s airlock where it will soon be placed in the vacuum of space and grappled by the Japanese robotic arm. The deployer will be maneuvered with the robotic arm and positioned away from the orbital outpost to safely release the tiny satellites into Earth orbit.

Onboard the orbital outpost are a variety of research freezers—large, small, portable, and permanent—that house and preserve station research samples for analysis both on Earth and in space. One of them, a smaller glovebox freezer, is being installed inside Kibo’s Life Science Glovebox (LSG) by NASA flight engineer Jessica Meir for upcoming experiment operations. The freezer’s location inside the LSG allows the samples to be stowed and frozen immediately after processing to prevent degradation and preserve integrity during sensitive biology research.

Meir also assisted flight engineer Sophie Adenot of ESA (European Space Agency) as she set up wearable devices for a pair of biomedical tests on Wednesday. Adenot first measured her blood pressure to calibrate the PhysioTool technology demonstration gear. Next, she wore head and body sensors that measured her brain oxygen and blood flow levels as she performed cognitive and mental tasks on a computer. Researchers are testing the portable device onboard the station to potentially monitor crew health on missions to the Moon, Mars, and beyond.

Meir also had time to help NASA flight engineer Chris Williams pack cargo inside a SpaceX Dragon cargo spacecraft that will undock from the Harmony module’s forward port and soon return to Earth. Williams then maneuvered into the Quest airlock and adjusted a spacesuit’s legs, arms, and helmet, then ensured the suit’s switches and valves were correctly configured ahead of an upcoming spacewalk.

On May 27, during routine operations of the International Space Station’s Canadarm2, the system demonstrated an elevated motor current in a wrist joint and arm motion did not occur as expected. NASA worked alongside CSA (Canadian Space Agency) to understand the issue and determined a spacewalk will be required to replace the joint using a spare already aboard the orbital complex. The Canadarm2, which is designed to be repaired in orbit, is in a safe configuration and standard operations using the arm have been paused. In the coming weeks, NASA will host a news conference to discuss the repair and preview the planned Tuesday, June 30 spacewalk. NASA will share more on the spacewalkers closer to the activity.

Roscosmos cosmonauts Sergey Kud-Sverchkov and Sergei Mikaev joined each other and explored space physics in the Zvezda service module. The duo observed how two different sized spheres drift freely in microgravity with no pushing movement from the crew. Results may lead to the design of newer space tools, improved robotics, and a deeper understanding of crew motion. Roscosmos flight engineer Andreu Fedyaev focused primarily on maintenance testing computer operations, cleaning ventilation systems, and transferring water between station tanks.

Finally, the space station is orbiting higher today after the Progress 95 cargo spacecraft fired its thrusters for over eight minutes early Wednesday raising its altitude by 1.9 miles. This adjusts the orbital outpost’s altitude ahead of the launch and docking of the Soyuz MS-29 crew spacecraft planned for mid-July.

Learn more about station activities by following the space station blog, @space_stationon X, as well as the ISS Facebook and ISS Instagram accounts.

Get the latest from NASA delivered every week. Subscribe here.

The post Expedition 74 Works Scientific Installs, Suit Prep Ahead of Canadarm2 Repair Spacewalk appeared first on NASA Science.

Microbiology and human research were the main scientific focus aboard the International Space Station on Tuesday to protect health on and off the Earth. The Expedition 74 crew members also worked on advanced research hardware and sent down a congratulatory message to the Artemis III crew, who were named during an announcement from the Johnson Space Center in Houston.

Some common bacteria have shown an increased resistance to antibiotics in the space environment potentially affecting an astronaut’s ability to fight an infection. Flight engineers Jack Hathway of NASA and Sophie Adenot of ESA (European Space Agency) explored the antibiotic-resistant organisms inside the Kibo laboratory module’s Life Science Glovebox and the Harmony module’s maintenance work area by processing the microbial samples and preparing them for DNA extraction and analysis. Doctors will use the data to understand how microbes adapt to microgravity possibly informing countermeasures to reduce the risk to astronaut health and protect patients on Earth.

NASA flight engineers Jessica Meir and Chris Williams partnered together loading a CubeSat-packed small satellite orbital deployer into Kibo’s airlock that will soon be placed into the vacuum of space. The Japanese robotic arm will grapple the deployer and point it away from the orbital outpost where it will safely deploy the shoebox-sized satellites into Earth orbit. A series of tiny satellites will be released for public and private research, including the Hokushin-1 CubeSat that will test space technologies such as radio frequency, propulsion, and solar arrays.

Roscosmos cosmonauts Sergey Kud-Sverchkov and Andrey Fedyaev worked on a pair of different investigations on Tuesday to continuously monitor how weightlessness affects the human body. Kud-Sverchkov, the orbital outpost’s commander, strapped an acoustic sensor around his neck that recorded his rapid exhalation to learn how living in space affects the respiratory system. Fedyaev wore a set of cuffs attached to his arms, wrist, and fingers measuring his blood pressure for a microgravity cardiac experiment. Roscosmos flight engineer Sergei Mikaev was back on artificial intelligence research studying new tools to boost crew efficiency and communications aboard a spacecraft.

Four of the station’s astronauts also sent down a message congratulating the four new Artemis III crew members commander Randy Bresnik of NASA, pilot Luca Parmitano of ESA, and NASA mission specialists Frank Rubio and Andre Douglas. The four flight engineers each spoke a few inspiring words with Meir stating, “Congratulations, Artemis III and godspeed on the journey ahead.” Watch the crew message on @Space_Station X.

Learn more about station activities by following the space station blog, @space_stationon X, as well as the ISS Facebook and ISS Instagram accounts.

Get the latest from NASA delivered every week. Subscribe here.

The post Crew Works Microbiology, Advanced Tech and Congratulates New Artemis III Crew appeared first on NASA Science.

Expedition 74 began the week bioprinting human cartilage tissue and harvesting alfalfa plants aboard the International Space Station to advance health and promote self-sustainable space crews. The orbital residents also retrieved materials exposed to the external space environment and conducted their own ultrasound vein scans to continuously learn how living in space affects physics and biology.

NASA flight engineer Jessica Meir opened up the Kibo laboratory module’s Life Science Glovebox on Monday and set up a bioprinter to produce viable cartilage tissues aboard the orbiting laboratory. NASA flight engineer Chris Williams assisted Meir collecting the frozen cartilage samples for thawing then mixing the living cells with a gel-like bioink for placement in a printing cartridge. The biotechnology study tests the manufacturing of cartilage in weightlessness to increase its stability for printing on demand implants using a patient’s own cells to treat a range of health conditions.

Earlier, Williams began his shift with NASA flight engineer Jack Hathaway harvesting alfalfa plants inside the Columbus laboratory module’s Veggie facility. The astronauts collected the plants and roots for photographing, placed the botanical samples inside foil, then stowed them inside a science freezer for later analysis for the Veg-06 study. Insights may lead to the development of advanced methods to grow plants for food on future space missions.

Afterward, Hathaway scanned Williams neck, shoulder, and leg veins using the Ultrasound 3 biomedical device as doctors on the ground monitored in real time. Roscosmos cosmonauts Sergey Kud-Sverchkov and Sergei Mikaev also took turns scanning each other’s veins with the Ultrasound 3. The ultrasound imagery will help researchers protect crew members from space-caused blood clots.

Flight engineer Sophie Adenot of ESA (European Space Agency) and Meir joined each other during the first half of their shift retrieving containers of samples from Kibo’s airlock that were placed outside the orbital outpost for a materials exposure test. The samples included radiation shields, crew suit fabrics, optical fibers, and more to help engineers build robust technologies that can survive harsh environments both on Earth and in space.

Sergey Kud-Sverchkov and Sergei Mikaev, the orbiting lab’s commander and flight engineer, spent the majority of their shift inspecting and servicing the Zvezda service module’s treadmill. The space station’s other treadmill, COLBERT, is located in the Tranquility module.

Roscosmos flight engineer Andrey Fedyaev spent the first half of his shift locating and identifying computer components and video gear in the Zarya module to update the station’s inventory management system. Fedyaev wrapped up his day studying using artificial intelligence tools to boost crew efficiency and communications.

Learn more about station activities by following the space station blog, @space_stationon X, as well as the ISS Facebook and ISS Instagram accounts.

Get the latest from NASA delivered every week. Subscribe here.

The post Crew Begins Week with More Cartilage Printing and Plant Harvesting appeared first on NASA Science.

The Zvezda service module’s transfer tunnel, known as the PrK, on the International Space Station has experienced cracks since 2019 that have resulted in small atmosphere leaks and prompted ongoing monitoring and repair efforts by Roscosmos. NASA and Roscosmos have worked together to identify the root cause while Roscosmos has been applying leak mitigation measures, including temporary and permanent sealants.

The week of June 1, during Progress 95 spacecraft cargo operations, Roscosmos noted an increase of the previous leak rate to two pounds per day and identified new suspected leak areas in the PrK. Following this observation, Roscosmos made the decision to begin work toward a more extensive inspection and structural repair effort Friday morning. This revised approach involved cutting a bracket to better access an area identified as a possible leak source for further inspection, using a method that could have resulted in elevated risk to the structure in the area. In response, NASA directed the four SpaceX Crew-12 members and NASA astronaut Chris Williams, who flew to station aboard the Soyuz MS-28 spacecraft, to take a heightened safety posture, known as a safe haven, inside the SpaceX Dragon spacecraft during the procedure.

Later Friday morning, Roscosmos paused and did not perform the structural repair work in favor of conducting additional measurements and data assessments, which included inspection of suspected areas of interest and review of areas where sealant was previously applied. NASA strongly supported that decision, and as a result, following that decision, Crew-12 and Williams ended their safe haven activities and returned to normal operations aboard the orbiting laboratory.

NASA will continue to work with our Russian counterparts, along with the rest of the international partners that support the space station, to assess and ensure a resolution to this matter.

Learn more about station activities by following the space station blog, @space_stationon X, as well as the ISS Facebook and ISS Instagram accounts.

Get the latest from NASA delivered every week. Subscribe here.

The post NASA Provides Update on Space Station Leak appeared first on NASA Science.