Ofcom concerned TikTok’s age verification is ineffective, leaving some exposed to posts on suicide, self-harm and pornography
TikTok is under formal investigation over concerns it has failed to protect children from harmful content, the UK’s online regulator, Ofcom, has announced.
The social media platform’s approach to checking the ages of users has sparked “particular concerns” at the watchdog, almost a year after measures to protect children from the worst of online content came into effect under the Online Safety Act.
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© Photograph: True Images/Alamy
© Photograph: True Images/Alamy
© Photograph: True Images/Alamy
A newly published study in Nature Metabolism reports that brown fat can act as a hub of molecular messaging, using secreted microRNAs to coordinate physiology across the body. Researchers focused on brown adipose tissue—well known for its role in thermogenesis—and asked whether it also participates in long-distance communication via RNA signals.
To visualize and track these messages, the team employed brown-fat–specific RNA labeling in living systems. This strategy allowed them to connect RNA production within adipocytes to downstream effects elsewhere, moving beyond correlations toward a clearer map of inter-organ RNA traffic.
The central finding is the presence of a communication network mediated by microRNAs released from brown fat. These small regulatory RNAs appear to travel beyond the tissue of origin and engage gene-regulatory pathways in other organs, effectively relaying information about metabolic state.
Functionally, the work supports a model in which microRNA “dispatch” from thermogenic fat tunes cellular programs in remote targets. Such programs likely involve post-transcriptional regulation, a process microRNAs are known to influence by pairing with complementary sequences in messenger RNAs.
Importantly, the approach does not treat microRNAs as generic circulating molecules. Instead, the labeling confirms their brown-fat origin and strengthens the link between secretory RNA dynamics and systemic physiological outcomes.
The study also highlights the specificity of the messaging: not all RNAs are equally represented, and the labeled microRNA repertoire points to organized, tissue-defined signaling rather than random leakage.
Beyond mapping pathways, the results carry implications for metabolic disease research. If brown fat microRNAs can reshape gene expression in other organs, manipulating these signals could offer a route to modulate energy balance, insulin sensitivity, or inflammatory tone.
For now, the findings provide a blueprint for how RNA labelling combined with tissue specificity can uncover hidden layers of endocrine-like communication. As techniques improve, the field may move toward a broader “RNA connectome” linking organ behavior through secreted regulatory molecules.
Researchers describe their results as evidence that brown fat is not only a metabolic engine but also an information broadcaster. In the evolving landscape of viral-style science news, this discovery underscores how tiny RNA molecules can orchestrate large-scale biological conversations.
Subject of Research: Inter-organ communication via secreted microRNAs from brown adipose tissue.
Article Title: Brown fat-specific RNA labelling reveals a network of inter-organ communication by secreted microRNAs.
Article References: Lino, M., Palermo-Ruiz, G., Efthymiou, V. et al. Brown fat-specific RNA labelling reveals a network of inter-organ communication by secreted microRNAs. Nat Metab (2026). https://doi.org/10.1038/s42255-026-01558-0
Image Credits: AI Generated
A Comissão Europeia aprovou o plano de ação submetido pela rede social X para resolver as infrações ao DSA detectadas em dezembro de 2025. A plataforma tem seis meses para implementar as medidas e submeter uma auditoria independente, mas o Conselho para os Serviços Digitais considerou o plano apenas "parcialmente adequado".
The post Bruxelas aprova plano da rede social X para cumprir regras europeias sete meses após multa de 120 milhões appeared first on Tek Notícias.
Se você curte o Sonic e os games clássicos dele, conheça e veja como instalar o jogo Sonic Robo Blast 2 no Linux via Flatpak.
Leia o restante do texto "Como instalar o jogo Sonic Robo Blast 2 no Linux via Flatpak"
O post Como instalar o jogo Sonic Robo Blast 2 no Linux via Flatpak apareceu primeiro em Blog do Edivaldo - Informações e Notícias sobre Linux.
A family of 18 from Gaza has won the right to come to Britain with "access to public funds" after winning a human rights challenge in the British courts.
The post Family of 18 From Gaza Wins Human Rights Challenge to Allow Them to Come to Britain appeared first on The Daily Sceptic.
Conheça o Nokia 300 4G, feature phone com bateria enorme e função powerbank para carregar outros dispositivos.
O post Nokia 300 4G Powerbank: bateria gigante e lanterna integradas apareceu primeiro em Blog do Edivaldo - Informações e Notícias sobre Linux.
At the Royal College of Nursing meeting last month, top of the agenda was not the recruitment crisis or NHS waiting lists but climate change. Have nurses nothing better to do, asks Professor Roger Watson.
The post Have Nurses Nothing Better to Do Than Discuss Climate Change? appeared first on The Daily Sceptic.
Thousands of fossilized bones from a Cretaceous-period bonebed in Wyoming, the United States, offer rare physical evidence that Tyrannosaurus rex fed on the carcasses of a duck-billed dinosaur species called Edmontosaurus annectens.
The post Tyrannosaurus rex Scavenged Duck-Billed Dinosaurs in Ancient Wyoming, Bite Marks Reveal appeared first on Sci.News: Breaking Science News.
A dried-out felt-tip marker and a snapped-off piece of molded black plastic sold for $857,600 at a Sotheby's auction on Wednesday.
What otherwise might have been worthless bits of trash commanded the highest bids due to where the two items were 57 years ago—lifting off aboard NASA's Apollo 11 spacecraft on humanity's first mission to land astronauts on the Moon. More than flown odds and ends, one was the problem that almost stranded Neil Armstrong and Buzz Aldrin on the lunar surface, and the other was the simple solution to saving the mission.
"Houston, Tranquility. Do you have a way of showing the configuration of the engine arm circuit breaker?" radioed Aldrin to Mission Control after realizing he or Armstrong had inadvertently broken off the top of the circuit breaker switch that would enable their ascent engine to ignite, beginning their trip back to Earth. "The reason I'm asking is because the end of it appears to be broken off. I think we can push it back in again. I'm not sure we could pull it out if we pushed it in, though."
© Sotheby's
A dried-out felt-tip marker and a snapped-off piece of molded black plastic sold for $857,600 at a Sotheby's auction on Wednesday.
What otherwise might have been worthless bits of trash commanded the highest bids due to where the two items were 57 years ago—lifting off aboard NASA's Apollo 11 spacecraft on humanity's first mission to land astronauts on the Moon. More than flown odds and ends, one was the problem that almost stranded Neil Armstrong and Buzz Aldrin on the lunar surface, and the other was the simple solution to saving the mission.
"Houston, Tranquility. Do you have a way of showing the configuration of the engine arm circuit breaker?" radioed Aldrin to Mission Control after realizing he or Armstrong had inadvertently broken off the top of the circuit breaker switch that would enable their ascent engine to ignite, beginning their trip back to Earth. "The reason I'm asking is because the end of it appears to be broken off. I think we can push it back in again. I'm not sure we could pull it out if we pushed it in, though."
© Sotheby's
This week, the Coalition for Independent Technology Research (CITR) won a key battle in its fight to reverse a visa-restriction policy that the Trump administration had used to attempt to revoke green cards and deport non-US citizens who work on misinformation, disinformation, fact-checking, content moderation, compliance, and trust and safety.
In an opinion published Tuesday, US District Judge James Boasberg granted a preliminary injunction blocking the State Department from enforcing the policy until the CITR’s lawsuit is resolved.
On its face, the policy does not require visa denials or deportations. Instead, it authorizes immigration investigations into individuals suspected of helping foreign adversaries attempt to manipulate public opinion by suppressing US speech.
© UCG / Contributor | Universal Images Group
Jurassic Park, while beloved as a film, has been the subject of snarky memes for the infamous line in which one of the characters declares, "This is a Unix system, I know this!" while using a computer with an unusual 3D file manager interface.
Despite the memes, the film's production team was meticulous in accurately sourcing the right PCs (and adjacent details) for the sets—not too much of a surprise, given writer Michael Crichton's background with computing and his obsessive attention to detail in the book the film is based on.
© Universal Pictures
Jurassic Park, while beloved as a film, has been the subject of snarky memes for the infamous line in which one of the characters declares, "This is a Unix system, I know this!" while using a computer with an unusual 3D file manager interface.
Despite the memes, the film's production team was meticulous in accurately sourcing the right PCs (and adjacent details) for the sets—not too much of a surprise, given writer Michael Crichton's background with computing and his obsessive attention to detail in the book the film is based on.
© Universal Pictures
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