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What people eat throughout life may influence more than heart health, weight, and blood sugar. A growing body of research is examining whether food choices can also affect how quickly the brain changes as people grow older. This question matters because dementia already affects tens of millions of people worldwide. With no simple way to [β¦]
In 1948, Muriel Howorth was living a relatively ordinary life in the seaside town of Eastbourne on the south coast of England when she received a letter that would completely change the trajectory of her life.
From an early age, she had wanted to take part, or as she put it, βbe of useβ in international affairs. During World War II, she was employed by the Ministry of Information, the government office primarily responsible for wartime publicity and propaganda in the UK.Β
Howorth must have been talented at promotion and publicity, because the letter that arrived in 1948ββout of the blue,β according to her personal papersβinquired if she would like to apply her talents to making atomic energy seem more friendly.
She was well-educated, but not terribly knowledgeable about atomic science, so she borrowed a book by the radiochemist Frederick Soddy, who was born in Eastbourne, titled The Interpretation of Radium. Within a few chapters, she found herself a true believer in the promise of the atom. She would devote the rest of her life to sharing the wonders of atomic science with anyone who would listen.Β
Nuclear energy gets a rebrand after WWII
The United States dropped atomic bombs on the Japanese cities of Hiroshima and Nagasaki on August 6 and 9, 1945, a key factor in the end of World War II. The scale of the destruction and the ongoing damage from nuclear fallout after these attacks was vast. Despite the devastation, when a Gallup poll was released in mid-August of 1945, 85 percent of Americans approved of the bombing.
The atom was more or less a mystery to the average American, and was seen both as something to be feared and a source of hope. The potential for nuclear energy seemed endless, and although the Soviet Union was Americaβs ally, establishing a lead over the Soviets in nuclear technology seemed prudent.
Around 1900 when this photo was taken, nearly all grapefruits were yellow. The popular Rio red grapefruit wasnβt developed until 1984 using atomic gardening. Image: Contributor / Getty Images / Rykoff Collection
Muriel Howorthβs pro-nuclear childrenβs book and atomic gardening
In the years after World War II, American and European scientists and heads of state agreed that there should be a focus on more productive and peaceful uses for atomic power. The letter that Howorth received in 1948 was part of this effort. She threw herself into projects that combined science education and entertainment.
Notable among these was an elaborately choreographed pantomime titled Isotopia: An Exposition on Atomic Structure. Howorth also self-published a childrenβs book featuring Daddy Proton, Mummy Neutron, and their electron children. Her greatest impact as an early science communicator, though, was her work in atomic gardening.Β
Irradiated peanuts and other miracles of atomic gardens
Applying radiation to agricultural plants was, in part, a response to wartime scarcity. Restricted rations had made people acutely aware of the possibility of food insecurity. Researchers hoped that exposure to gamma radiation might induce mutations that resulted in higher-yielding or disease-resistant crop varieties. Perhaps some of those crops might be more dense in nutrients, too.
As atomic ambassador, Howorth founded the Atomic Gardening Association and recruited hundreds of membersβor, as she called them, βatomic mutation experimenters.β Soon, atomic gardening kits were available to the public. One could send away for packets of seeds from an irradiated plant. By planting these seeds and propagating multiple generations of the plants, home gardeners could test whether any useful-seeming mutations had arisen.
Howorth herself served a mutated variety of Carolina peanuts to some of her scientist friends in 1959. Their response was underwhelming, so she planted the rest of the peanuts in her garden, where they grew remarkably quickly and produced extremely large peanuts. She usually kept a handful of these extra-large peanuts tucked away in her handbag in case the opportunity arose to recruit a new member to the Atomic Gardening Association.
In the June 1961 issue of Popular Science, a story promotes buying βplant atomic energized flower and vegetable seedsβ as an βamazing science buy.β Image: Popular Science, June 1961 issue
Howorthβs lasting legacy to citizen science
Itβs tempting to view Howorth as a kooky eccentric. Contemporary newspaper reports of her various events and projects were certainly dismissive in tone. More accurately, she represents an early effort at addressing the gap between scientific research and public understanding.
The world was far less interconnected in her day, with no internet, no omnipresent news media, and no social media platforms. Not only that, but the idea of women as integral parts of scientific research was slow to catch on, despite pioneering work by scientists like Marie Curie and Rosalind Franklin.Β
Today, the same gulf exists between what scientists publish in their fields and what the average person understands. The same challenge of translating scientific language for public consumption exists for science communicators, but the tools available to them have evolved beyond recognition. You can find videos and posts by scientists explaining everything from how blimps work to what various chemical reactions look like, or from how fossils form to why black holes are so dark.
If Howorth were around today, her atomic choreography might have gone viral. As it stands, she was a wonderful example of the love of sharing knowledge with the public, and of the excitement and joy that comes with learning new things about how our world works.Β
In That Time When, Popular Science tells the weirdest, surprising, and little-known stories that shaped science, engineering, and innovation.
Many things change in space, including how the intestines function. Constipation is a known side effect of space travel, but until now, little has been known about why it happens. Constipation is a familiar problem for astronauts, but the biological reason it develops during spaceflight has remained uncertain. Researchers from the University of Copenhagen working [...]
A compound produced in the body after eating pomegranates improved heart function by up to 80% in experimental models of a type of heart failure with limited treatment options. For people with heart failure with preserved ejection fraction, the heart can still pump blood but struggles to relax and refill properly between beats. In experimental [...]
A lot of us like to start our days with a cup of coffee. Whether itβs a pour-over you make at home or a latte from your favorite coffee shop, many people need caffeine to wake up and feel alert.Β
If you rely on coffee as a productivity hack, you might be wondering if thereβs a time of day that would optimize its effects on the brain. It turns out the answer isnβt that straightforward. How the body reacts to caffeine depends on factors such as age, metabolism, and tolerance. So, hereβs what the experts say about how to time that cup of joe.Β
What effect does coffee have on the body?Β
Caffeine is the central stimulant found in coffee and other foods like tea, soda, and chocolate. It helps us feel more awake by blocking adenosine, a naturally occurring chemical that builds up in the brain while weβre awake. Experiencing morning grogginess, or sleep inertia, is related to residual adenosine in the brain, though other factors like your sleep quality also play a role.Β As adenosine builds up throughout the day, it makes us feel increasingly tired and helps signal to the brain that itβs time for sleep.Β
Since caffeine has a similar chemical structure to adenosine, it fits into the same receptors in the brain. When caffeine binds to these receptors, it blocks adenosine from doing its job. As a result, the brain receives fewer of the signals that make us feel tired, helping us feel more awake, alert, and energized.Β Β
Caffeine is the central stimulant found in coffee. Video: How does caffeine keep us awake? β Hanan Qasim, TED-Ed
βBut this perceived energy does come at a cost,β says Dustin Lee, an assistant professor of psychiatry and behavioral science at Johns Hopkins, in an email to Popular Science. The brain adapts to these conditions incredibly well, so over time, the brain produces more adenosine receptors.Β
The more receptors your brain has, the more caffeine it needs to feel alert, eventually leading to caffeine tolerance and withdrawal. βWithdrawal symptoms, which Iβm sure most of us have some familiarity with, include headache, irritability, fatigue, and difficulty concentrating,β Lee explains.Β
If you want to quit caffeine or miss your usual cup of joe, then youβre likely to experience these symptoms very quickly. They usually start within 12 to 24 hours after stopping caffeine, peak within 48 hours and resolve within two to nine days.Β
When should you drink coffee?Β
βThereβs no set answer for everyone,β says Marie-Pierre St-Onge, a professor of nutritional medicine at Columbia University Medical Center, to Popular Science. It depends on your age, metabolism, and caffeine tolerance.Β
βPeak caffeine absorption occurs rapidly, at about 30 to 60 minutes after ingestion,β says Lee, so a simple answer to the question would be to drink coffee about an hour before whatever activity that would benefit from caffeineβs stimulating effects. If youβre going on a run, for example, you might want to get some caffeine in before heading out, says St-Onge. Thatβs why its use is limited by some sports governing organizations like the National Collegiate Athletic Association.Β
You shouldnβt really need caffeine right when you wake up, as your body should already be alert, says St-Onge. βIf youβre starting to feel a slump a few hours after waking up, that would be when to drink coffee.βΒ
Both Lee and St-Onge stress that the answer to when you should drink coffee really depends on the individual. The ability to metabolize caffeine slows down with age, so the amount of time to clear caffeine from your bloodstream gets longer as you get older. Your circadian rhythm also changes as you get older, which means you might get tired earlier in the day.Β
βCompounded, [these changes] make it so that you would want to consume your caffeine earlier as you get older,β explains St-Onge.Β
βCaffeine dose matters just as much as the time at which you drink your cup of coffee,β adds Lee.Β
A cup of coffee can actually have a wide range of caffeineβthe dose can depend on the ratio of coffee to water, how you brewed your cup, and even bean type. And βtolerance has a major effect on caffeineβs effects, so the morning cup of coffee might serve more to partially reverse overnight caffeine withdrawal, so that should be taken into consideration as well,β he says. Basically, that means that for regular coffee drinkers, the first cup of the day is contributing to reversing the effects of not having had any caffeine since the day before.Β
When should you not drink coffee?
βNot too close to bedtime,β says St-Onge. If youβre finding that youβre having trouble falling asleep, make sure that youβre not drinking coffee too late in the afternoon.Β
Drinking coffee on an empty stomach can also be too abrasive for some people, and may lead to side effects like increased jitters and an increased urge to go to the bathroom. (Though the idea that it can lead to stomach ulcers is a myth.) If youβre someone with a sensitive stomach, try eating something alongside your cup of coffee to be safe.Β
So, donβt fret too much the next time youβre thinking of when to have a cup of coffee. Just remember: not too late, and not too much. Then you might become dependent on the stuff.Β Β
In Ask Us Anything, Popular Science answers your most outlandish, mind-burning questions, from the everyday things youβve always wondered to the bizarre things you never thought to ask. Have something youβve always wanted to know? Ask us.
A compound connected with foods such as pomegranates and walnuts could point scientists toward a new treatment for one of the most stubborn forms of heart failure. Researchers found that urolithin A helped stiff heart tissue relax and reduced several damaging changes linked to the disease. Urolithin A is not simply a nutrient that comes [β¦]
Intelligence is an energetically expensive luxury β as the rise of artificial intelligence has reminded us. The human brain is no exception. Comprising roughly 2% of the body weight, it uses one fifth the bodyβs energy in the resting state β compared with less than half of this in non-human primates. A five-year-old child devotes [β¦]
Scientists have theorized for decades about how the human brain evolved and grew dramatically in size. Now, new research points to one common ingredient that may have played a crucial role in the brainβs evolution over time: sugar.
A research team at the University of Sydney and the University of Glasgow created a model comparing modern nutrition with that of our ancestors over a span of four million years. The findings suggest that our ancestors relied on naturally occurring carbohydrate-rich foods, which could have played an important role in not only their overall dietary nutrition but also the evolution of the human brain.
These new findings challenge an older scientific model that emphasizes meat as a primary driving force behind human evolution.
βRaw starch does not release glucose, meaning early humans likely relied on naturally sweet foods long before grains became a regular part of the diet,β said lead author Professor Jennie Brand-Miller, Professor of Human Nutrition at the University of Sydney Charles Perkins Center and School of Life and Environmental Sciences, in a statement.Β
While meat played a role in our ancestorsβ diets, the new research suggests that the amount of energy required by a growing brain also needs to be considered. Throughout human evolution, brain size increased from roughly 300 grams in early hominins to approximately 1,500 grams in modern humans. Glucose is the brainβs primary energy source, creating increasing nutritional demands as brain size grew over time.
βWhile animal foods were important, the brainβs need for glucose has largely received little attention from anthropologists,β Professor Brand-Miller said.Β Β
The Research
To better understand this hypothesis, the team created a model encompassing six evolutionary stages. Researchers estimated the βobligatory glucose demandβ of the brain and other glucose-dependent tissues, including red blood cells, kidneys, and reproductive tissues. They then compared these glucose requirements with the carbohydrate sources that would have been readily available to humans during different stages of evolution.
βThe human brain is unusually large for our body size and requires substantial amounts of energy,β Professor Brand-Miller said.Β βGlucose is the brainβs primary energy source, and for much of human evolution, would have come from carbohydrates found in foods such as fruit and honey.βΒ
The model incorporated evidence from numerous fields, including metabolism, food composition, fossil isotope studies, dental morphology, archaeology, primate diets, and genetics.
Overall, the research suggests that early hominins, including Australopithecus, Homo habilis, and Homo erectus, were highly dependent on carbohydrate-rich foods, with fruit representing an important source. Later, as humans began using fire to cook food, starch-rich plants could also provide significant amounts of glucose. Grains, meanwhile, appear to have entered the human diet much later. The researchers point to archaeological evidence of seed grinding dating to around 65,000 years ago.
βPeople often think of carbohydrates as breads and cereals, but for most of human evolution carbohydrates came from fruits, honey and underground plant foods,β said Professor Brand-Miller. βThe earliest evidence of seed grinding is 65,000 years ago, when we see the first evidence of grinding stones to make flour.βΒ
The study also examined the role of glucose in reproduction and pregnancy. Pregnancy and lactation significantly increase glucose demands, since energy is required not only by the mother but also by the developing fetus and placenta, as well as for milk production.
The new findings may also help explain humansβ longstanding attraction to sweet foods. For much of human evolution, naturally sweet foods such as fruit and honey provided concentrated sources of energy while also supplying fiber, vitamins, minerals, and other nutrients.
That doesnβt mean people should start making a run for the candy aisle. The findings do not suggest that modern humans should consume more refined sugar. Instead, the researchers distinguish between naturally occurring sugars found in whole foods and highly processed foods containing large quantities of added sugar.
Sugar was also not the human brainβs only source of fuel, nor were carbohydrates the sole dietary factor influencing human evolution. Rather, the researchers argue that glucose requirements have often received less attention than other dietary factors, including meat, fat, and protein. Our ancient appetite for naturally sweet, carbohydrate-rich foods, however, may have helped fuel the extraordinary expansion of the human brain.
Chrissy Newton is a PR professional and the founder of VOCAB Communications. She currently appears on The Discovery Channel and Max and hosts theΒ Rebelliously Curious podcast,Β which can be found onΒ YouTubeΒ and on all audio podcast streaming platforms. Follow her on X:Β @ChrissyNewton,Β Instagram:Β @BeingChrissyNewton, andΒ chrissynewton.com. To contact Chrissy with a story, please email chrissy @ thedebrief.org.
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A team of researchers from the University of Sydney and the University of Glasgow argues that dietary sugars, not animal foods, may have played the decisive role in the expansion of the human brain over the past 4 million years, as hominin brain size grew nearly fivefold, from about 300 grams in early relatives like [β¦]
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Childrenβs eating habits may shape their heart health decades later, according to a major new study. Scientists found that people who regularly drank sugary beverages while growing up were more likely to develop high blood pressure as adults, while choosing whole fruit instead appeared to lower that risk. The findings were published in Circulation by [β¦]