After nearly two decades of work, scientists have completed a wiring diagram of the central nervous system of an adult male fruit fly (Drosophila melanogaster).
The post Researchers Unveil Complete Fruit Fly Connectome appeared first on Sci.News: Breaking Science News.
In a development that could reshape how chemists recycle one of the most persistent classes of synthetic molecules ever made, researchers have reported a new catalytic strategy that strips fluorine atoms from perfluoroalkyl chains in a controlled, sequential fashion while installing a single boron group at the chain’s terminus. The work, published in Nature Communications, introduces what the authors call zipper polydefluorination-monoborylation, a transformation that walks down a perfluoroalkyl skeleton and removes multiple fluorine atoms in a stepwise cascade before capping the partially defluorinated product with a boron substituent. The achievement addresses a longstanding challenge in fluorine chemistry: while carbon-fluorine bonds are prized in materials and pharmaceuticals for their extraordinary stability, that same stability makes them notoriously difficult to break selectively, leaving chemists with few tools for converting perfluorinated waste streams into useful building blocks.
Perfluoroalkyl substances, often grouped under the umbrella of PFAS chemistry, owe their remarkable properties to the strength of the carbon-fluorine bond, which at roughly 485 kilojoules per mole in fully fluorinated chains ranks among the strongest single bonds that carbon forms. This bond strength, combined with the sheer electronegativity of fluorine, means that perfluoroalkyl groups resist oxidation, hydrolysis, and thermal degradation under nearly all conventional conditions. As a consequence, perfluorinated chains accumulate in the environment and resist standard degradation pathways, prompting intensive research into defluorination methods ranging from photocatalytic single-electron transfer to reductive hydrodefluorination with metal hydrides. Yet most existing approaches suffer from a common limitation: they either remove fluorine indiscriminately, collapsing the entire chain to a mixture of products, or they remove only a single fluorine atom, offering little control over the degree of defluorination. The new study demonstrates a way to achieve the best of both worlds, delivering multi-fluorine removal in a predictable pattern while simultaneously introducing a versatile functional handle.
The conceptual heart of the method lies in what the authors describe as a zipper mechanism. Rather than removing fluorine atoms at random positions along the chain, the reaction initiates at a defined site and then propagates along the perfluoroalkyl backbone one carbon at a time, much as a zipper opens tooth by tooth. At each step along the chain, a fluorine atom is expelled and replaced in sequence, with the reaction front advancing until a thermodynamic or kinetic stopping point is reached. The monoborylation component of the process ensures that once the zipper has run its course, the resulting olefinic or anionic intermediate is intercepted by a boron reagent, furnishing a product in which the boron group occupies a predictable position derived from the original perfluoroalkyl terminus. Organoboron compounds are among the most valuable intermediates in modern synthetic chemistry, serving as partners in Suzuki-Miyaura cross-coupling and as precursors to alcohols, amines, and halides, so their installation at a defluorination site effectively converts a chemical dead end into a synthetic launching pad.
Mechanistically, the transformation draws on the characteristic reactivity of organoboron reagents toward geminal difluoroalkenes, the partially defluorinated intermediates that arise when consecutive fluorine atoms are eliminated from a perfluoroalkyl chain. Perfluoroalkyl chains, when subjected to strong bases or reductive conditions, can undergo sequential beta-fluoride elimination events, each generating a more highly unsaturated species. The boron reagent in the reported system engages these unsaturated intermediates through addition pathways that install boron at the terminal carbon while generating a carbanionic center adjacent to the remaining difluoromethylene unit. That newly formed carbanion is perfectly positioned to expel another fluoride ion, regenerating an unsaturated handle one carbon further down the chain and setting up the next iteration of the cycle. This intimate coupling of borylation and defluorination is what gives the reaction its chain-walking character: each borylation event creates the conditions for the next defluorination event, and the process ripples along the chain until the fluorine reservoir is exhausted or the reagents are consumed.
The practical significance of the work becomes apparent when one considers the fate of the fluorine atoms themselves. In the zipper process, fluorine is released as fluoride ion, which under the reaction conditions is sequestered by silicon-containing trapping agents to form robust silicon-fluorine bonds. Fluorosilicates of this kind are stable, isolable, and, importantly, compatible with industrial processes for recycling fluorine back into hydrofluoric acid, the feedstock from which essentially all synthetic organofluorine compounds are made. In this sense, the method does more than transform perfluoroalkyl chains into borylated products; it also lays the groundwork for closing the fluorine cycle, recovering the fluorine content of persistent molecules in a form that can be fed back into the chemical economy. With global concern over PFAS contamination intensifying and regulatory pressure on fluorinated chemicals mounting, technologies that enable fluorine recovery rather than dilution into the environment carry considerable weight.
From a synthetic chemistry standpoint, the products of the reaction open multiple downstream avenues. Because the boron substituent is installed at a defined position on a partially fluorinated alkyl or alkenyl framework, the resulting molecules retain a programmable mixture of carbon-fluorine bonds and carbon-boron functionality. The remaining fluorine atoms can tune the lipophilicity, metabolic stability, and dipole moment of the scaffold, properties that are actively exploited in medicinal chemistry when designing fluorinated drug candidates. Meanwhile, the boron group serves as a convertible handle, allowing the defluorinated carbon center to be joined to aromatic rings through cross-coupling, oxidized to alcohols, or aminated in homologation reactions. In effect, the method converts a chemically inert perfluoroalkyl group, useful mainly as a passive coating or tail, into a functionalized partial-fluoro skeleton that can participate in the full toolkit of carbon-carbon and carbon-heteroatom bond formation.
The reported study also sheds light on the factors governing how far the zipper travels along a given chain. Chain length, the nature of the substituent anchoring the perfluoroalkyl group, and the stoichiometry of the base and boron reagent all influence the number of fluorine atoms removed and the distribution of products obtained. Through systematic variation of these parameters and careful analysis of the reaction mixtures by nuclear magnetic resonance spectroscopy and mass spectrometry, the authors map out the scope of the transformation across a range of perfluoroalkyl substrates, from short perfluoroethyl groups to longer chains approaching those found in commercial fluorosurfactants. Control experiments interrogating individual elementary steps support the proposed sequential elimination-addition mechanism and rule out alternative pathways involving radical fragmentation or random beta-scission, underscoring the unusually high degree of positional control the method achieves.
Beyond its immediate synthetic utility, the work contributes to a growing body of research aimed at taming the carbon-fluorine bond through the strategy of defluorinative functionalization. Over the past decade, chemists have developed an impressive repertoire of reactions that replace fluorine in perfluoroalkyl and fluoroarene substrates with groups ranging from hydrogen to sulfur, nitrogen, and carbon substituents. What distinguishes the zipper approach is its multiplicity and its directionality: instead of a single substitution event at a single site, the reaction performs many substitutions in a choreographed sequence along a chain, effectively treating the perfluoroalkyl group as a one-dimensional lattice to be patterned at will. This conceptual reframing, from defluorination as bond-breaking to defluorination as programmable editing, may inspire analogous strategies for other polyfluorinated motifs, including perfluoroarenes and perfluoropolyethers, two additional classes of highly persistent fluorinated materials.
Challenges remain before such chemistry can move from the laboratory bench to environmental remediation at scale. The reaction conditions reported rely on strong bases and moisture-sensitive boron reagents handled under inert atmosphere, and the substrates studied are discrete, soluble perfluoroalkyl compounds rather than the polymeric or adsorbed PFAS species that dominate environmental contamination. Scaling the chemistry will require sourcing boron reagents economically, managing the large quantities of fluoride generated, and integrating the transformation with upstream methods for extracting perfluoroalkyl pollutants from water and soil. Nevertheless, the demonstration that a perfluoroalkyl chain can be unzipped in a controlled manner, with fluorine captured in recyclable form and a valuable boron handle installed, establishes a credible chemical pathway toward defluorination that is both productive and selective, a combination that has eluded the field for decades.
As policymakers and scientists grapple with the legacy of fluorine chemistry, work of this kind illustrates a middle path between the wholesale abandonment of fluorinated molecules and their indefinite persistence in the biosphere. The fluorine atom confers properties that industry and medicine continue to depend upon, and the ability to disassemble fluorinated architectures on demand, recovering both the carbon skeleton as a functionalized building block and the fluorine content as a recyclable salt, points toward a more circular future for organofluorine chemistry. The zipper polydefluorination-monoborylation strategy reported in Nature Communications is an early but striking example of that vision made concrete at the molecular level, and it is likely to prompt rapid efforts to extend the concept across the breadth of persistent fluorinated chemicals.
Article Title: Zipper polydefluorination-monoborylation of perfluoroalkyl chains
Article References: Albers, S. L., Harzendorf, J. K., Deliaval, M., Köllmann, J., & Streuff, J. (2026). Zipper polydefluorination-monoborylation of perfluoroalkyl chains. Nature Communications, 17(1), Article 9502. https://doi.org/10.1038/s41467-026-77437-9
Image Credits: AI Generated
DOI: 10.1038/s41467-026-77437-9
Keywords: perfluoroalkyl chains, defluorination, polydefluorinative borylation, organoboron compounds, carbon-fluorine bond activation, PFAS degradation, fluorine recycling, geminal difluoroalkenes, cross-coupling, sustainable chemistry
Tyrannosaurus rex fossils are relatively common finds, with dozens of variously complete examples on display in museums around the world. But T. rex tracks? That’s an entirely different story. Even when stomped into the mud by a 17,500-pound apex predator, dinosaur footprints rarely last long enough to fossilize over millions of years.
That’s what makes a recent discovery in southwestern North Dakota so remarkable. Paleontologists from the Denver Museum of Nature & Science and Liverpool John Moores University in England have documented not one, but four footprints preserved along a 23-foot-long path within the famous Hell Creek Formation. The prints are the first known trackway made by an adult T. rex, and are described in a study recently published in the Journal of Vertebrate Paleontology.
While rare, T. rex footprints are distinctive for their massive size and narrow toes. In this case, each dino-stomp measures about three feet long. Paleontologists identified the roughly 66.5-million-year-old path last year on federal land near the town of Marmath, North Dakota, near the state’s southwestern border with Montana. After carefully clearing the surroundings, researchers imaged each footprint using a high-resolution 3D surface scanner. This allowed the team to digitally analyze the scene, as well as create physical reproductions.
The two left and right imprints suggest that the dinosaur was a sizable adult with an estimated 13-foot stride—but paleontologists don’t think this particular T. rex was in much of a hurry. Based on the gait, it was likely moseying around at 3.5 to 4.5 miles per hour, or about the same speed as a human going on a power-walk. Given the tracks’ weathering and erosion, the team stresses their theorized speed is somewhat speculative.
Paleontologists are now planning to excavate three of the four footprints later this year, then transfer them by helicopter to the Denver Museum of Nature & Science.
“Bones tell us an enormous amount about these animals, but footprints capture a moment of behavior. With a trackway, we can actually follow an animal as it moved across the landscape,” Tyler Lyson, a Denver Museum of Nature & Science paleontologist and study co-author, said in a statement. “That is incredibly rare for T. rex.”
The post Paleontologists discover first adult ‘T. rex’ footpath appeared first on Popular Science.
Global warming will soon cross a critical threshold, surpassing a dangerous limit set years ago, the United Nations Environment Programme (UNEP) has found. But experts say it's still possible to cool things back down, emphasizing that the stakes are too high to stop trying.
In 2015, 196 nations and territories signed the Paris Agreement, pledging to restrict the average rise of global temperatures to below 2 degrees Celsius (3.6 degrees Fahrenheit) above pre-industrial levels. Ideally, the rise was meant to be kept to 1.5 degrees C (2.7 degrees F) above those levels. However, according to a new report detailed by the UNEP, we are on track to cross that 1.5 C line — and soon.
"This summer's scorching heat, raging wildfires and deadly floods are a warning of what lies ahead. We must make the overshoot above 1.5 degrees as small and short as possible. That demands an overshoot of ambition," U.N. Secretary-General Antőnio Guterres said in a statement.
According to the new report, experts have found that if we as a planet continue with business as usual, not only will we pass 1.5 C, but it will happen within just a few years. The report, however, maintained a positive tone. Rather than simply predicting a doomsday plot, the main purpose of this release is to outline a pathway with the necessary steps to set things on the right track.
"As global temperature rise gets set to cross 1.5°C, pushing climate risks and impacts to dangerous new heights, the world must strive to return to below 1.5°C as soon as possible and simultaneously reduce the vulnerability of societies, communities and economies to climate impacts," the report, titled "Limiting Overshoot: Navigating exceedance of 1.5°C and pathways towards return," states in its abstract.
Climate change is primarily caused and driven by human activities like transportation, industrial manufacturing, agriculture and more. According to the report, the two main aspects of this work need to be: reducing emissions and enabling adaptations to protect people impacted by the effects of climate change.
The U.N. states in the report the necessity of both an immediate and sustained reduction in the emissions of greenhouse gases like methane and carbon dioxide. Not only do we need to find a way to cut emissions fairly immediately, but we also need to find a way to sustain that effort over time. The U.N. further states it is important to not only work toward removing carbon from the atmosphere, eventually reaching net-negative emissions where more emissions are removed by humans from the atmosphere than added to the atmosphere.
This sort of carbon capture technology is still fairly early in its development, but according to the U.N., it is essential we find ways to rapidly move toward a future where we can capture and store carbon from the air and therefore reduce the quantity of greenhouse gases around our planet.
In addition to these long-term emission reduction actions, in this report the U.N. has also asserted that this process will need to include "adaptation actions," or ways to support the many people and communities already affected by climate change.
Even if all of the world's nations start working immediately to drastically reduce emissions, we are already seeing the sometimes fatal and irreversible effects of climate change. From increasing the intensity of wildfire seasons to worsening natural disasters, climate change is far from a distant future. It's our reality, especially for those living in high-risk areas like coastlines. So, while the nations of the world need to work together to reduce emissions, it is also important that adaptations are found to reduce the existing and future impacts of climate change on our communities.
"There are no good outcomes if we remain above 1.5°C. Across the globe, extreme heatwaves are already proving that climate impacts will strike faster, hit harder, and last longer — costing more lives and causing deeper disruption," Inger Andersen, the Executive Director of UNEP, said in the same statement. "Now is the time we must double down on climate action. We can — and must — get on the right path. By cutting greenhouse gas emissions, strengthening resilience and adaptation, and ensuring exceedance of 1.5°C is as small and short as possible."
A conversation with neuroscientist and author Antonio Damasio about intelligence, feelings, and robots
The post Does Consciousness Require a Body? appeared first on Nautilus.
A single manufacturing step can now do something that normally takes two separate chemicals. It makes a material bright white and water-repellent at the same time, without using either titanium dioxide or PFAS. Researchers at Kyoto University say the technique could remove two of the materials industry’s most persistent chemical dependencies in one move.
Professor Easan Sivaniah, at Kyoto University’s Institute for Integrated Cell-Material Sciences, led the project with collaborators from Tokyo Metropolitan University and Donghua University. The team calls the resulting process Deep Foam Photolithography.
Titanium dioxide has long served as the default white pigment across packaging, films, and coatings. The European Union recently banned its use as a food additive, though, over safety concerns. PFAS compounds face a parallel reckoning. These fluorinated chemicals give materials their water- and oil-repellent properties, yet mounting evidence of their environmental persistence has manufacturers worldwide hunting for substitutes.
Sivaniah’s team set out to solve both problems using physics rather than chemistry. Rather than finding safer replacement chemicals, they asked whether a material’s structure alone could deliver the same effects.
The underlying phenomenon is called structural whiteness, and it appears throughout nature without any pigment involved at all. Snow, sea spray, and clouds all owe their brightness to how light scatters off foam-like structures made mostly of air. That same principle is at work in plant tissues and the protective nests certain frogs build.
That principle even shows up in centuries-old art. The blinding white of the waves in Hokusai’s The Great Wave off Kanagawa comes entirely from light scattering off bare washi paper fibers. The print itself contains no white ink at all.
Researchers engineered porous structures that replicate this same light-scattering effect, drawing additional inspiration from how light interacts with leaves and flower petals in nature.
Making the material requires just two steps. Light exposure first breaks a polymer down into smaller molecular fragments. A mild solvent treatment then causes those fragments to react and swell, forming an open, porous structure throughout the material.
That single process yields two properties at once. Internally, the porous structure scatters light to produce bright whiteness with no added pigment whatsoever. On the surface, that same structure becomes rough enough to repel water and oil, mimicking the effect seen on a lotus leaf.
Working with textile researchers at Donghua University, the team confirmed the process works on fabrics in addition to printable polymer films. Crucially, it required no newly invented specialty chemicals, succeeding instead with polymers already available commercially.
The resulting platform supports printing resolutions up to 20,000 DPI while delivering structural whiteness and water repellency together, all without titanium dioxide or PFAS. Rather than relying on added pigments or persistent chemical coatings, the approach builds both color and function directly into a material’s physical structure. That points toward a lighter, more sustainable way to manufacture everyday materials.
Solar system simulations starting from varied initial conditions suggest that Earth-like planets can emerge naturally from planet formation. Computer simulations of planetary systems can now begin from thousands of different starting conditions, allowing researchers to explore how worlds might emerge without assuming the final outcome. Over the past three decades, these models have advanced from [...]As the 2026-2027 NFL season kicks off, the Philadelphia Eagles are giving new meaning to their signature “Fly, Eagles, Fly” fight song. The football team is partnering with the National Marine Sanctuary Foundation for Birds Supporting Birds, an initiative to support seabirds off the coast of Massachusetts (and in New England Patriots’ territory) this fall.
The team is supporting NOAA’s Stellwagen Bank National Marine Sanctuary Shearwater Tagging Project, an ongoing initiative dedicated to studying the great shearwater (Ardenna gravis) and their migration. Great shearwaters are large, white-and-grey seabirds known for their epic journeys. They travel thousands of miles every year from their remote South Atlantic breeding grounds up to the cooler North Atlantic waters during the nonbreeding season. According to the National Marine Sanctuary Foundation, they fly the equivalent of over 200,000 football fields across the Atlantic Ocean every single year.
Birds Supporting Birds will help support researchers in Stellwagen Bank, an 842-square-mile marine sanctuary east of Boston, to tag great shearwaters and track their migratory routes across the Atlantic.
“The Eagles are directly funding researchers to attach lightweight, solar-powered satellite transmitters to great shearwaters,” Joel R. Johnson, President and CEO of the National Marine Sanctuary Foundation, tells Popular Science. “These tags track the birds’ migration patterns around the Eastern Seaboard and down to the Southern Atlantic Ocean in real time.”
Lovingly known as “The Birds” by their incredibly devoted fanbase, the football team is leveraging their platform to bring attention to ocean conservation and highlight environmental stewardship.
A major 2015 study found that the Gulf of Maine is warming faster than 99 percent of the ocean due to climate change. While the water has slightly cooled since 2021, a report published by NOAA in July found that the environment in the Gulf of Maine still remains unstable. These changes in ocean temperature, currents, and other conditions can impact the seabirds’ food supply.
Great shearwaters are reliable indicators of an ecosystem’s health, who rely on small fish called sand lance in their diets. Whales, dolphins, bluefin tuna (Thunnus thynnus), and other key Gulf of Maine species also rely on these fish belonging to the family Ammodytidae in their diets. By studying great shearwaters and their health, researchers can better understand what is happening in the local ecosystem as a whole.
Researchers at Stellwagen Bank National Marine Sanctuary used satellite tracking technology in 2013. These tags are lightweight and attached to the birds with degradable thread. They have small solar panels so scientists can monitor the birds’ routes over extended periods.
Researchers have now deployed tags on Phil, Franklin, Hoagie, and Liberty, four great shearwaters with very Philly-appropriate names.
“We are thrilled to invite the public to follow Phil, Franklin, Hoagie, and Liberty in real time on our interactive maps and social channels, bringing everyone along on our shared mission to protect our ocean waters and marine life,” says Johnson, who lists bald eagles (Haliaeetus leucocephalus), great blue herons (Ardea herodias), and great shearwaters among his favorite birds.
Live interactive maps will be available soon on the Stellwagen Bank National Marine Sanctuary and National Marine Sanctuary Foundation’s website, so you can follow the great shearwater’s epic journey, while the Eagles (or your favorite team) compete on the gridiron.
The post ‘Birds Supporting Birds’ connects the Philadelphia Eagles with migrating seabirds appeared first on Popular Science.
A viral video shows sprinklers soaking a green lawn outside a denver data center during severe water restrictions.
The science of getting Z’s has progressed rapidly in recent years. A growing body of research links poor sleep to increased risk of cognitive decline, a higher likelihood of Alzheimer’s disease, and even greater chances of developing heart problems. At the same time, wearables, like smart rings and watches, are transforming the way everyday people view sleep, turning their resting hours into rich datasets to pore over, sometimes to unhealthy obsessive levels.
What’s still less understood, is how the subtle, everyday fluctuations in sleep quality that come from simply living a normal life can alter brain chemistry. People don’t live in controlled lab settings, and even the most avid bio-optimizer still has nights where quality sleep takes a backseat. Actually understanding how someone’s day-to-day sleep patterns affect their brain chemistry would require putting them in an MRI machine and collecting data over and over again, over long stretches of time to get a more holistic view.
That’s exactly what Auburn University electrical and computer engineering graduate student Joshita Majumdar signed up for. Over 76 weeks, Majumdar slipped into the university’s 7-Tesla MRI scanner 104 times. That’s a level of commitment that would make even a stalwart Zen meditator fidget with frustrated boredom. Thankfully, Majumdar had a special companion to accompany her during the loud, cramped, 90-minute sessions: the hit television sitcom Friends.
Majumdar recalls how a screen in the machine would cycle through four 10-minute videos of the staple from the 90’s and early 2000’s, each made up of several different scenes clipped together. The idea was twofold. Majumdar needed something playing during the sessions that would keep her from getting bored, and Friends just happens to be her self-described “guilty pleasure.” It was also one of the first shows she connected with as an international student adjusting to her early days in the United States, so some scenes strike particularly nostalgic, emotional notes. And like any great sitcom, Friends runs the gamut from numbing brain-rot to tear-jerking sentimentality. That’s potentially a great backdrop for a study analyzing changes in brain chemistry.
“If you’re happy, you watch Friends. If you’re sad, you watch Friends,” Majumdar tells Popular Science. “So all times [are] a good time to watch Friends, right?”
Past studies have looked at the way sleep variability affects brain chemistry, but many of those involve intentionally depriving the subject of sleep. This longer-term approach takes a more subtle approach that should better reflect the nuances of everyday life.
“This is a person living her life, going through normal ups and downs and we are seeing how brain chemistry responds to that,” Majumdar’s advisor and Auburn University Electrical and Computer Engineering Professor Gopikrishna Deshpande said. “That’s what makes this dataset so powerful. It’s not artificial. It’s not forced. It’s real.”
Majumdar grew up in Kolkata, West Bengal, India, and moved to the U.S. in 2016 to pursue a master’s degree in engineering at the University of Georgia, with an emphasis on mechanical engineering. Early on, she became interested in how different environmental factors affect brain function. And while she was busy pushing forward with her rigorous academic work, she also dealt with occasional homesickness, living in a new country thousands of miles away from friends and relatives.
Around that same time, Majumdar says she started watching Friends to see what all the fuss was about. People around her seemed obsessed with the show, but she hadn’t seen it, and initially didn’t really understand the hype. Eventually, she went back to the show with fresh eyes and everything clicked. The sarcastic Chandler Bing (Matthew Perry) and affable actor Joey Tribbiani (Matt LeBlanc) are among her favorite characters.
“I gave it another try, and then I was like, oh no, this is fun,” Majumdar said. “And then it became a guilty pleasure.”
When it came time to pick a test subject for this new, lengthy MRI study, Majumdar says Dr. Deshpande asked her if she’d be up for volunteering. Majumdar has some experience with MRI machines from past projects, enough to know that she wasn’t prohibitively claustrophobic or bothered by the machine’s loud industrial noises. Still, nothing she’d done before this could compare to the endurance and commitment it would take to see this through. The team decided not to commit to a set number of scans at the onset, and took it day by day to see how much the grad student could handle.
“We said, like, ‘Okay, we’ll take one day at a time, one week at a time, and see how far we can pull it through,” Majumdar explained.
Majumdar was the one who pitched playing Friends episodes in the machine. She compiled four 10-minute videos, each made up of different scenes from various episodes. The material ran the gamut in tone, with the goal of eliciting a range of brain responses. One particularly strategic choice was to include clips of episodes aired around Thanksgiving. These fan-favorites tend lean heavily on themes of family, friendship, and camaraderie. Friends, in other words, was meant to roughly simulate the backdrop for Majumdar’s everyday life brain state.
“In a task-based MRI, we are giving a particular stimulus, so we kind of have an idea what we are trying to activate in the brain,” Majumdar said. “But in a naturalistic run, it’’s kind of like you’re putting yourself into a real-world situation.”
But that wasn’t all. Every session, the team would also play a roughly four-minute music video to the song “Love You Zindagi,” from the 2016 Bollywood film Dear Zindagi. Similar to the Thanksgiving episodes, this video was thoughtfully selected for its depiction of friends and family. It also helps remind Majumdar of home.
“I have left my friends and family back in India,” Majumdar said. “So depending upon what my emotions are on that day, I used to really connect to it differently each day.”
Majumdar and her colleagues quickly settled into a routine for their MRI odyssey. She would come to the university’s neuroimaging center on Tuesdays and Thursdays, typically around 7:30 in the evening. She had the choice of that later time slot or first thing in the morning, but chose the former because she says she isn’t really a morning person. That choice came with some trade-offs, though.
Early on, she discovered that eating a meal immediately before entering the machine made her feel dizzy. After one fraught experience, she made a point of giving herself a gap of 90 minutes to two hours after eating before going into the scanner. Coming in later at night, especially after a long day of PhD work, also meant she sometimes had to fight the urge to fall asleep. Even though she was stuck in the machine for 90 minutes at a time, the tests required that she keep her eyes open for the vast majority of it. That struggle is partly what makes subsequent findings all the more interesting.
“Sometimes I was a little bit sleepy, but that’s part of it,” Majumdar said. “And that’s the thing that we wanted to bring out through this research: that you are in a very natural setting. You’re not in a kind of a forced experiment where you are either sleep-deprived or put under some conditions that might evoke a different brain response. We really wanted to look at the real-world condition where I’m just living my life, and in parallel I’m getting scanned and seeing how the brain chemistry responds to it.”
In addition to sitting in the MRI machine, Majumdar logged everything she ate and wore a sleep-tracking ring. With all of that data, the team was able to match each night’s sleep metrics with the next day’s scan and compare patterns over time. Though there’s still data being combed through, they’ve already found an important connection: across the 104 sessions collected over 76 weeks, nights with less deep sleep and more light sleep tended to be followed by higher glutamate levels the next day. Glutamate is an amino acid that acts as a kind of chemical messenger in the brain. In a previous university blog post, Majumdar compared this finding to the brain flushing out byproducts that build up during active, wakeful moments, allowing for a more restful night’s sleep.
“You wake up with a fresh mind,” she said. “But if that process is blocked, it’s going to hamper you the next day.”
Majumdar’s work in this area has only just begun. Moving forward, she and her colleagues hope to bring on more study participants to make the dataset even richer, though they’ll likely make adjustments so that each participant doesn’t have to go in for scans quite as often as she did.
Eventually, she says she also hopes to use AI and other tools to try and extract the feelings and emotions experienced during those MRI sessions (and during certain Friends’ moments) to get a better sense of what’s happening in the brain when certain feelings are evoked.
Miraculously, even after watching the show in a cramped, rumbling tube for 18 months, Majumdar says she still isn’t sick of Friends. When asked if she can still watch the silly sitcom without getting bored, Majumdar responds with an emphatic,
“Yes, definitely.”
The post Classic sitcom ‘Friends’ helps grad student endure 104 brain scans appeared first on Popular Science.
In July, the Trump administration relegated endangered leatherback turtles, sea lions, and whales to mere collateral damage in its race to profit from the oceans. Now, fisheries science is in the government’s crosshairs.
The National Oceanic and Atmospheric Administration (NOAA) announced new agency priorities last week that they say are a commitment to “cutting bureaucracy, modernizing our science, and putting our fishing communities first.” But experts say the agency’s actions will erode fish stocks, threaten endangered species, and surrender marine habitats to destructive trawlers.
The agency-level reforms serve as a self-proclaimed “operational roadmap” to fulfilling President Donald Trump’s “Restoring American Seafood Competitiveness” executive order, signed in April 2025.
© Reinhard Dirscherl
In July, the Trump administration relegated endangered leatherback turtles, sea lions, and whales to mere collateral damage in its race to profit from the oceans. Now, fisheries science is in the government’s crosshairs.
The National Oceanic and Atmospheric Administration (NOAA) announced new agency priorities last week that they say are a commitment to “cutting bureaucracy, modernizing our science, and putting our fishing communities first.” But experts say the agency’s actions will erode fish stocks, threaten endangered species, and surrender marine habitats to destructive trawlers.
The agency-level reforms serve as a self-proclaimed “operational roadmap” to fulfilling President Donald Trump’s “Restoring American Seafood Competitiveness” executive order, signed in April 2025.
© Reinhard Dirscherl
Researchers developed a model showing how lava-covered planets close to their stars can hold onto their atmospheres, which could help guide the search for life beyond our solar system. Some planets orbit so close to their stars that intense radiation should strip away their atmospheres. Yet several of these scorching, lava-covered worlds still retain thick [...]How did you get on?
28 words Warming up nicely
38 words Getting hot, hot, hot
48 words Top dog!
Fancy some more? Check out our puzzles page.
The post Word flower puzzle no. 8 appeared first on Physics World.
A telescope with no moving parts, stationed in the mountains of British Columbia, has produced the largest single accounting of fast radio bursts ever assembled. The Canadian Hydrogen Intensity Mapping Experiment (CHIME) and its FRB collaboration have released a second catalog logging 4,539 fast radio bursts from 3,641 distinct sources, drawn from more than five years of continuous sky-watching between July 25, 2018, and September 15, 2023.
The result, posted to arXiv in January 2026 and published in The Astrophysical Journal Supplement Series, supersedes the collaboration’s first catalog, which covered a single year of observations ending in mid-2019 and recorded 536 bursts. The new release spans roughly five times the observing period and delivers more than eight times as many detected events, cementing CHIME’s role as the dominant instrument for cataloging these millisecond-long flashes of radio energy.
CHIME’s design is unusual for an instrument that has become the world’s leading fast radio burst detector. Located at the Dominion Radio Astrophysical Observatory near Penticton, British Columbia, it consists of four stationary half-pipe reflectors, each 100 meters long and 20 meters wide, laid side by side and oriented north-south. ICHIME has no moving parts at all — unlike dishes that swivel to track a target. Each cylinder’s focal line is strung with 256 dual-polarization antennas, for 1,024 across the array, feeding a digital signal-processing system that forms 1,024 beams electronically rather than through any physical steering.
That fixed geometry means CHIME cannot be aimed at a particular patch of sky the way a conventional radio dish can. Instead, it watches a roughly 200-square-degree strip of sky directly overhead and lets Earth’s rotation carry the rest of the northern sky through its field of view over the course of a day. The technique, known as transit observing, trades the ability to target specific objects on demand for near-continuous coverage of a wide swath of sky, night and day — precisely the kind of monitoring that catching rare, unpredictable millisecond bursts requires.
The collaboration’s first catalog, released in 2021, logged just over 500 bursts from a single year of data. That release established CHIME as a serious FRB survey instrument and provided the first large, uniformly selected sample for statistical study. The new catalog is a different scale of effort entirely: it folds in more than four additional years of observing time, past the original one-year window, and pushes the source count past 3,600 — a population increase that lets researchers move from spotting a phenomenon to characterizing it as a class.
Fast radio bursts are intense pulses of radio waves lasting typically a few milliseconds, first identified in archival data in 2007 and confirmed as an astrophysical population in the years since. Most detected bursts appear to flash once and never repeat from the same location, but a minority repeat, sometimes many times, from sources that can be pinpointed to host galaxies. Among the 4,539 bursts in the new catalog, 981 come from 83 known repeating sources, while the remainder appear as one-off events, at least within the observing window. That repeater fraction, drawn from a sample nearly nine times larger than before, gives researchers a substantially firmer basis for comparing the properties of repeating and apparently non-repeating bursts, including their durations, frequency structure, and the dispersion imposed on the signal as it crosses intervening plasma on its way to Earth.
The physical origin of fast radio bursts remains only partly settled. Magnetars — neutron stars with extraordinarily strong magnetic fields — are the leading candidate source for at least some bursts, following the 2020 detection of a burst from a magnetar inside the Milky Way. But the diversity of burst durations, brightness, and repetition behavior recorded across thousands of events suggests more than one physical mechanism, or more than one class of source, may be responsible. Larger, more uniform catalogs let researchers test that diversity statistically rather than relying on a handful of well-studied individual sources.
Because each burst’s radio signal is dispersed — delayed by different amounts at different frequencies as it passes through free electrons in space — the catalog also functions as a probe of matter distributed between galaxies. That diffuse, low-density gas is difficult to detect by any other means, and a sample of thousands of bursts at known or estimated distances allows astronomers to map its distribution across large volumes of the universe, an application sometimes described as using fast radio bursts to weigh the cosmos.
The catalog paper reports each burst’s arrival time, dispersion measure, scattering timescale, and flux density, along with a dynamic spectrum across the 400–800 megahertz band CHIME observes, at just under a millisecond time resolution. That level of detail, applied uniformly across thousands of bursts rather than compiled from disparate instruments and detection methods, is what distinguishes a catalog release from a series of individual discovery announcements.
CHIME/FRB’s outrigger stations — companion antenna arrays built at separate sites across North America — extend the core telescope’s ability to localize individual bursts to their host galaxies with far greater precision than CHIME alone can achieve, a capability that has already been applied to a subset of local-universe bursts drawn from the same multi-year dataset. As those outriggers accumulate their own detections alongside the main array, the size and precision of future catalogs are expected to grow further, sharpening the statistical picture the second catalog has already begun to draw.
The post Four fixed half-pipe reflectors in British Columbia, each 100 meters long and strung with 1,024 antennas, watched the same overhead strip of sky from July 25, 2018 to September 15, 2023 and logged 4,539 fast radio bursts from 3,641 separate sources, on a telescope that cannot be aimed. appeared first on Space Daily.
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