An oral GLP-1 drug showed promising weight loss results in a phase II trial. A pill-based approach to GLP-1 treatment helped adults with obesity or overweight lose as much as 12 percent of their body weight over 36 weeks, according to a randomized phase II clinical trial published in Nature Medicine. The study tested aleniglipron, [...]

Researchers have developed a visible-light-driven method that could help chemists build more complex drug-like molecules in fewer steps. A blue light commonly used in aquariums and indoor gardens could help chemists solve one of drug discovery’s persistent challenges: building more intricate molecules without adding a long series of costly reactions. Many medicines are based on [...]

A generic version of a breakthrough cystic fibrosis drug, manufactured in Bangladesh for a fraction of the American price, may give some families around the world an unlikely lifeline.

New findings indicate that finerenone may help protect kidney function and reduce major health risks in people with chronic kidney disease who do not have diabetes. Chronic kidney disease affects an estimated 800 million people worldwide and is one of the leading causes of kidney failure, cardiovascular complications, and premature death. Yet for many patients [...]