A large international study found that an experimental oral diabetes medication produced significant improvements in both glucose control and weight loss. For millions of people with type 2 diabetes, GLP-1 drugs have transformed treatment by helping lower blood sugar while also promoting weight loss. But many of the most effective options still require injections, creating [...]

An endocrinologist’s new weight-care system halted population-level weight gain and could reshape obesity treatment across America. For years, endocrinologist Leigh Perreault, MD, believed there had to be a more effective way to help people manage their weight than simply advising them to eat healthier and exercise more. “There was a moment I put my face [...]

Scientists found that a tomato-soy juice rich in plant-derived compounds altered inflammation-related signals in healthy adults with obesity. A new study found that drinking tomato-soy juice rich in health-promoting plant compounds reduced levels of inflammatory proteins in healthy adults with obesity after four weeks. The results suggest the beverage could serve as a functional food [...]

A new study suggests that lingering rheumatoid arthritis symptoms are not always caused by ongoing inflammation. For people with rheumatoid arthritis, lingering pain and fatigue are often assumed to be signs that inflammation remains active. But new research suggests the real culprit may sometimes lie elsewhere. Researchers at Semmelweis University report that sleep disorders, depression, [...]

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A widely prescribed class of weight-loss and diabetes medications may be doing more than improving metabolic health. Drugs such as Ozempic and Wegovy have transformed the treatment of obesity and type 2 diabetes, helping millions lose weight and improve metabolic health. But scientists are increasingly uncovering effects that extend far beyond the scale. Research has [...]

A new AI framework called MouseMapper allows scientists to examine disease-related changes across the entire body at cellular resolution. Obesity does much more than affect metabolism and fat storage. It also changes immune activity, nerve structure, and tissue organization throughout the body, raising the risk of conditions such as type 2 diabetes, cardiovascular disease, stroke, [...]

In a small clinical trial, researchers at the Ohio State University found that a tomato juice rich in lycopene and soy isoflavones lowered several proteins linked to chronic inflammation, raising hopes for food-based therapies.

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