An unusual immune signature in lung cancer has led researchers toward a potential therapy involving tumor microbes and MAIT cells. Bacteria living inside lung tumors may be doing more than simply occupying the tumor environment. In preclinical research from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy, researchers found that [...]

Scientists found that some inherited traits can bypass the traditional rules of genetics, revealing a surprising new layer of inheritance beyond DNA. For more than a century, Gregor Mendel’s laws of inheritance have served as the foundation of genetics. But new research suggests that inheritance can be more complicated than the DNA sequences passed from [...]

Tiny lab-grown brain models and the particles they release may reveal hidden differences among Alzheimer’s patients. Personalized treatment remains one of the biggest challenges in Alzheimer’s disease. Two patients can receive the same medication for symptoms such as depression, anxiety, or agitation and experience very different outcomes, leaving doctors with few ways to predict who [...]

New ACC/AHA cholesterol guidelines promote earlier detection, personalized risk assessment, and more aggressive LDL cholesterol lowering to reduce long-term cardiovascular disease risk. For decades, cholesterol management has been a cornerstone of heart disease prevention. Yet despite widespread awareness, cardiovascular disease remains the leading cause of death worldwide, and millions of adults continue to have cholesterol [...]