Researchers have captured the first atomic-level views of human SMUG1, a key enzyme involved in repairing damaged DNA. Every cell in your body is constantly battling damage to its DNA. Now, scientists have captured the first atomic level images of a key human repair enzyme in action, revealing how cells identify and remove some of [...]

A surprising backup pathway allows cells to make a crucial amino acid when their primary machinery fails. For decades, biologists believed cells had only one way to access a molecule they cannot live without. New research suggests they were wrong. Scientists at Montana State University have uncovered a previously unknown cellular survival pathway that allows [...]

A naturally occurring anti-inflammatory protein fragment is showing promise in early Parkinson’s disease research. Parkinson’s disease affects millions of people worldwide, yet current treatments mainly address symptoms rather than the underlying damage occurring in the brain. Now, researchers in Brazil have identified a promising new approach that targets a different aspect of the disease: inflammation. [...]

A copper-based drug helped the brain flush out Alzheimer’s toxins, cutting plaque buildup and improving memory in a promising new study. Scientists at Monash University have identified a promising new approach to tackling Alzheimer’s disease. In laboratory studies, a copper-delivering drug significantly lowered levels of toxic proteins linked to the disease while also improving long-term [...]

Semaglutide delivered dramatic weight loss and health benefits in adults over 65, offering new hope for healthier aging. A new analysis of data from the STEP clinical trial program suggests that semaglutide remains both effective and generally safe for older adults living with obesity. The research, conducted by Prof. Luca Busetto of the University of [...]

Researchers in Sweden have developed a machine-learning approach that embeds the laws of physics directly into neural networks. A new study from Chalmers University of Technology in Sweden shows that machine learning can become far more efficient when it starts with a built-in understanding of the laws of physics. Researchers found that giving an AI [...]

Bird flocks, bacterial swarms, and even crowds move according to interaction rules that appear to break one of physics’ most fundamental principles: Newton’s law of action and reaction. Birds can see much of what is happening around them, but when flying in a flock, they respond only to birds beside them or ahead of them. [...]

Scientists have found a way to make GPS remarkably accurate in city “urban canyons,” where navigation has long gone wrong. Most of us trust that the location shown by our GPS is accurate. But anyone who has tried navigating an unfamiliar city knows that is not always the case. You may be walking steadily down [...]

Oxford physicists have created an unconventional class of quantum superpositions from highly nonclassical states. Researchers at the University of Oxford have created a new class of quantum superpositions, including Schrödinger’s cat-like states, using building blocks that are themselves strongly nonclassical. The advance could support future quantum computing architectures based on more complex systems than conventional [...]

Researchers explored how different dietary changes could reduce the carbon footprint of food consumption. A single change at the dinner table could have a bigger climate impact than many people realize. Researchers in the UK found that replacing just one beef steak per week with salmon could significantly reduce food-related carbon emissions over time. In [...]

Researchers found that a magma’s thermal history may be a key factor in determining whether an eruption becomes more vigorous or remains relatively gentle. What happens deep beneath a volcano can determine whether an eruption unfolds as a slow-moving lava flow or explodes into towering fountains of molten rock. New research suggests that one overlooked [...]

A new satellite-based framework allows scientists to measure the changing rhythms of cities in near real time. Cities are often described as living systems, but until now that idea has mostly been a metaphor. Roads, buildings, parks, and neighborhoods change constantly, yet much of that activity is hard to see as it happens. By the [...]

Bumble bees demonstrated an unexpected ability to solve a novel object-based challenge without training. A bee’s brain is smaller than a sesame seed, yet in a new experiment, some bumble bees appeared to solve a problem that required more than simple instinct. They had to move an object into position, climb onto it, and use [...]

A newly identified sensory pathway links fine hairs to itch sensations, revealing an unexpected biological system that may contribute to chronic itching disorders and provide new targets for treatment. An itch can seem simple, but scientists are finding that the sensation is far more complex than it appears. Researchers at the University of Michigan have [...]

New research indicates that when it comes to heart health, the types of fruits and vegetables consumed may be just as important as the amount. Most healthy eating advice focuses on quantity: eat more fruits and vegetables, aim for five servings a day, and your heart will benefit. But new research suggests that when it [...]

A new study suggests that overstimulating key cancer-growth pathways, rather than shutting them down, could offer a novel way to target pancreatic tumors driven by KRAS mutations. New research points to a possible way to fight pancreatic cancer by turning the disease’s own growth signals against it. The research, published in the journal Aging, focused [...]

New research suggests that a common second-line blood pressure treatment may not be as kidney-friendly as previously assumed for some people with diabetic kidney disease. Blood pressure control is one of the most important ways to slow kidney damage in people with type 2 diabetes. But new research suggests that one of the most commonly [...]

JUNO’s first results have launched a new era of precision neutrino physics and brought scientists closer to solving the neutrino mass mystery. The Jiangmen Underground Neutrino Observatory (JUNO) has achieved its first major scientific milestone. On June 10, its debut physics result was featured as a cover article in Nature. Using 59 days of high-quality [...]

A major challenge to dark energy, the mysterious force believed to be driving the universe’s accelerating expansion, has been overturned by a new study. Astronomers say a new analysis has reinforced one of the most important discoveries in modern cosmology, finding that the universe is still expanding at an accelerating rate. The result counters a [...]

James Webb has revealed that the sunrise and sunset sides of WASP-121 b have surprisingly different atmospheres. Astronomers using the James Webb Space Telescope (JWST) have discovered striking differences between the morning and evening sides of the atmosphere of WASP-121 b, an ultra-hot gas giant located far beyond our solar system. The findings provide the [...]