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An unusual bacterium that penetrates and lives inside human cells may offer a new drug target

Research underway in the lab of Rebecca Alexander, a professor in Wake Forest University's Department of Chemistry, is shedding light on an unusual human bacterium, Mycoplasma penetrans. Alexander's work to understand how and why this unique pathogen acts as it does could one day lead to new classes of drugs that better target illnesses associated with this particular pathogen, as well as others that act similarly.

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A cellular threshold can determine whether herpesvirus becomes active or lies dormant

During the COVID-19 pandemic, we wore masks and kept 2 meters (6.6 feet) apart in an effort to reduce the spread of the tiny droplets we release into the air with every breath, conversation or cough. The main goal was to reduce the number of virus particlesβ€”known as virionsβ€”to which we were exposed. For each virus, a person must be exposed to a minimum infectious dose to develop disease, and in many cases, the larger the dose, the more severe the illness.

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