Cluster headache causes extreme pain, but its origins remain unclear. New research links the disorder to genetics, inflammation, and tobacco smoke exposure. Unlike an ordinary headache, a cluster attack typically erupts without warning and causes excruciating pain around one eye. Episodes can last from 15 minutes to three hours and often return at similar times [...]

A hidden molecular defect in inflammatory bowel disease may help explain why flare-ups can return even when patients appear well. Even when inflammatory bowel disease appears under control, intestinal cells may remain primed to die. In a WEHI-led study, researchers found this hidden molecular defect in patients with few or no symptoms, and higher levels [...]