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A global view of human centromere variation and evolution

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10841-9

Complete sequencing of more than 2,000 centromeres from diverse humans reveals structures and elevated mutation rates that shape the evolution of these critically important regions.
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Intestinal stem cells count self-renewal divisions to switch multipotency

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10814-y

In Drosophila, cell fate switching in adult intestinal stem cells is determined through an epigenetic mechanism in which these cells count divisions, switching from producing enterocytes to producing an enteroendocrine mother cell every ninth division.
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