Adam Overholtzer:

Corners!

Simon B. Støvring:

“We fixed corner radius” was a WWDC keynote highlight. Let that sink in.

Rudrank:

This should have been since macOS 26 #WWDC26

Folks getting excited for consistent corner radius 😂

Kuba Suder:

Ehh, no change here, RIP Intel Macs… stuck on the v1 Liquid Glass forever 🫤

There was so much demand for this that the Liquid Radius haxie exists. People were willing to disable FileVault and System Integrity Protection to get consistent window corners.

Previously:

• macOS Golden Gate 27 Announced
• Tahoe Window Corners
• WWDC 2026 Keynote

Update (2026-06-23): Marcin Wichary:

Then, there’s the website you’ve just seen: elaborate, with nice “before and after” animations, and a fun landing page. I thought the installation steps, given the complexity of the effort, were exemplary and even educational. There’s also a page listing all the apps confirmed to work, and a “How Liquid Radius limits its blast radius” (ha) section, revealing the author is clear-eyed about their work being a hack, and even the dimensionality of its hackiness. Even within the tool there are nice design details.

But, as I was exploring the site, I kept switching between “this is ridiculous!” (laudatory) and “this is ridiculous!” (derogatory) in my head.

A new study reporting in Translational Psychiatry suggests that a traditional medicinal formulation called Rannasangpei—and particularly its constituent crocin-1—may help blunt autism-like behaviors triggered by prenatal exposure to valproic acid (VPA). The work frames autism-related impairments not only as behavioral phenomena, but also as downstream consequences of disrupted redox balance and chronic neuroinflammatory signaling in the brain.

The researchers used a VPA-induced model to mimic key aspects of autism-like neurodevelopmental disruption. Within this framework, they assessed whether Rannasangpei components could restore biological stability and translate into measurable improvements in behavior. The experimental logic is straightforward: if oxidative stress and neuroinflammation are causal amplifiers, then reducing them should lead to behavioral rescue.

A central finding is that treatment with Rannasangpei correlated with reduced oxidative stress markers. Oxidative stress is increasingly viewed as a bridge between genetic/environmental risk and neuronal dysfunction, because reactive oxygen species can disturb synaptic integrity, neuronal maturation, and signaling cascades essential for social and cognitive behaviors.

Equally important, the study reports a suppression of neuroinflammation. Neuroinflammation can reshape neural circuits through glial activation and altered cytokine profiles, potentially worsening developmental trajectories. By dampening inflammatory responses, crocin-1–linked effects appear to protect the brain environment during a sensitive developmental window.

The authors also emphasize that crocin-1’s contribution is not merely supportive but functionally significant, consistent with the bioactive chemistry of crocins that have been studied for antioxidant and anti-inflammatory activity. In this sense, the paper positions crocin-1 as a mechanistic candidate within a multi-component formulation.

Importantly for translational enthusiasm, the results connect molecular readouts to behavior, strengthening the argument that the observed changes are not cosmetic. Instead, they suggest an integrated pathway: oxidative imbalance and inflammatory tone shift in parallel with autism-like phenotype severity.

Overall, the study adds to a growing viral science-news narrative in neurodevelopment: natural compounds may modulate the biological “stress–inflammation” axis that shapes risk models like VPA. While animal data cannot be directly generalized to humans, the mechanistic coherence makes crocin-1 and Rannasangpei an attention-worthy direction for future preclinical and clinical exploration.

In the meantime, the headline is clear: Rannasangpei and crocin-1 show promise in reducing VPA-induced autism-like behaviors by calming oxidative stress and neuroinflammation, bringing a traditional medicine ingredient into modern neurobiological spotlight.

Subject of Research: Autism-like behaviors induced by valproic acid; oxidative stress and neuroinflammation
Article Title: Rannasangpei and its constituent crocin-1 ameliorate valproic acid–induced autism-like behaviors accompanied by reduced oxidative stress and neuroinflammation.
Article References: Qiu, R., Li, L., Yao, T. et al. Transl Psychiatry (2026). https://doi.org/10.1038/s41398-026-04283-0
Image Credits: AI Generated
DOI: https://doi.org/10.1038/s41398-026-04283-0

A new study in npj Urban Sustainability points to the practical levers that determine whether stormwater systems actually deliver long-term sustainability. As cities expand and rainfall extremes intensify, green and nature-based infrastructure has been promoted to capture runoff, reduce flooding, and protect water quality. But the research warns that success is not automatic: design decisions and operational realities can make or break performance.

The authors, Sun, Randrup, Blecken and colleagues, analyze what they call “decisive factors” governing sustainable stormwater management. Their central message is that the most visible features—such as bioswales, permeable surfaces, or detention basins—only work when supported by the right planning assumptions and measurable hydrological outcomes.

A key technical theme is how stormwater must be matched to system capacity under changing conditions. The study emphasizes that system sizing, soil or media properties, and infiltration or storage behavior strongly influence whether the infrastructure can handle typical storms and rare, high-intensity events. When these factors are misestimated, treatment efficiency can collapse during peak flows.

Equally important are maintenance and lifecycle considerations. Sustainable stormwater is sensitive to clogging, sediment accumulation, vegetation health, and changes in catchment behavior. The research highlights the need for maintenance regimes that reflect likely failure modes, rather than generic schedules that ignore local hydrology and traffic or land-use impacts.

The paper also stresses the value of monitoring and model-informed decision-making. Reliable data on rainfall patterns, runoff routing, and pollutant loads allow managers to validate performance and adjust operations. This feedback loop helps prevent long-term degradation that otherwise remains invisible until issues become costly.

For cities seeking viral, widely transferable “what works” guidance, the authors’ findings offer a shortlist of priorities: realistic capacity planning, robust material characterization, design for multi-storm performance, and maintenance strategies tied to specific mechanisms. Together, these elements translate sustainability goals into systems that function under real weather and real urban change.

The study’s DOI is 10.1038/s42949-026-00448-4.

Subject of Research: Sustainable stormwater management / urban sustainability
Article Title: Decisive factors in sustainable stormwater management
Article References: Sun, Z., Randrup, T.B., Blecken, GT. et al. Decisive factors in sustainable stormwater management. npj Urban Sustain 6, 104 (2026). https://doi.org/10.1038/s42949-026-00448-4
Image Credits: AI Generated
DOI: https://doi.org/10.1038/s42949-026-00448-4