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Small-molecule modulation of Ξ²-arrestins

βœ‡Nature
By: Alem W. Kahsai Β· Natalia Pakharukova Β· Henry Y. Kwon Β· Kunal S. Shah Β· Caroline T. del Real Β· Bowie N. Shreiber Β· Jason G. Liang-Lin Β· Paul J. Shim Β· Mason A. Lee Β· Van A. Ngo Β· Allison M. Schwalb Β· Uyen Pham Β· Anand Chundi Β· Haoran Jiang Β· Emmanuel Flores-Espinoza Β· Samuel Liu Β· Preston C. Nibley Β· Dana K. Bassford Β· Hyunggu Hahn Β· Cal A. Kunzle Β· Brittany N. Thomas Β· Jihee Kim Β· Yang Zhou Β· Jialu Wang Β· Xingdong Zhang Β· Jeffrey S. Smith Β· Lindsay A. M. Rein Β· Alex R. B. Thomsen Β· Sudha K. Shenoy Β· Sudarshan Rajagopal Β· Lei Shi Β· Seungkirl Ahn Β· Howard A. Rockman Β· Ali Masoudi Β· Robert J. Lefkowitz

Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10683-5

Integrated pharmacological, biochemical, biophysical and structural analyses of small-molecule Ξ²-arrestin inhibitors show how they block Ξ²-arrestin engagement with activated GPCRs, revealing their mechanism of action and uncovering a previously unrecognized allosteric regulatory site.
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Stability of inverted perovskite solar cells: a focus on interface phenomena

βœ‡RSC - Energy Environment
By: Hui Li Β· Yang Zhou Β· Annamaria Petrozza

Energy Environ. Sci., 2026, Advance Article
DOI: 10.1039/D5EE07642K, Review Article
Open Access Open Access
Hui Li, Yang Zhou, Annamaria Petrozza
The review offers a perspective on degradation in inverted PSCs, tracing the progression from intrinsic instabilities of interfacial materials to interface-amplified degradation in the perovskite absorber.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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