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Small-molecule modulation of Ξ²-arrestins

Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10683-5

Integrated pharmacological, biochemical, biophysical and structural analyses of small-molecule Ξ²-arrestin inhibitors show how they block Ξ²-arrestin engagement with activated GPCRs, revealing their mechanism of action and uncovering a previously unrecognized allosteric regulatory site.
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Inhibition of shuttle effect in organic cathode and in situ mechanistic exploration

Energy Environ. Sci., 2026, Accepted Manuscript
DOI: 10.1039/D6EE00605A, Paper
Yanxiang Gong, Yiran Jia, Jie Yang, Jun Zhang, Meng Xia, Xi-Yang Wang, Yunsheng Wang, Ying Tao, Manman Fang, Quan-Hong Yang, Ben Zhong Tang, Zhen Li
Organic p-type cathode materials are promising for sustainable energy storage due to their abundance, environmental compatibility, and high operating voltages exceeding 3.5 V. However, their application is constrained by high...
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Bridging redox asymmetry in hot and cold cells for boosted power density in thermally regenerative flow batteries

Energy Environ. Sci., 2026, 19,3878-3890
DOI: 10.1039/D5EE07558K, Paper
Huan Gao, Yuhao Cai, Wei Xiao, Mingming Yin, Minjie Liu, Tianshou Zhao, Haoran Jiang
Thermally regenerative flow batteries (TRFBs) offer a promising route for harvesting low-grade waste heat; however, their power output is limited by the mismatch in redox reaction kinetics during the reverse reactions between the cold and hot cells.
The content of this RSS Feed (c) The Royal Society of Chemistry
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The critical role of surface dipoles in CsPbI3 perovskite solar cells

Energy Environ. Sci., 2026, 19,2863-2873
DOI: 10.1039/D5EE07787G, Paper
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ran Ji, Nathaniel Gallop, Shivam Singh, Richard Beier, Yitian Du, Zongbao Zhang, Fulya Koc, Marielle Deconinck, Vladimir Shilovskikh, Jose Roberto Bautista-Quijano, Boris Rivkin, Yana Vaynzof
Finely modulating the Cs : Pb ratio of the top 1 nm of CsPbI3 leads to strong surface dipoles that alter the work function by more than 2 eV, increasing the power conversion efficiency from ∼10% to ∼20% and critically affecting stability.
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