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Structural basis of the RNA-editing cascade in trypanosome mitochondria

Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10831-x

Cryo-electron microscopy sheds light on the architecture of the Trypanosoma brucei mitochondrial editosome and reveals how this assembly mediates mRNA editing through the insertion and deletion of uridine nucleotides.
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<i>CHPO</i> coordinates chilling recovery and nitrogen use in rice

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10682-6

A rice gene, CHPO, links chilling resilience with nitrogen-use efficiency, revealing a domestication-shaped regulatory mechanism that could guide breeding of climate-resilient, sustainable rice varieties.
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A first-in-class pulsatile FXR agonist for bile-acid-related liver diseases

Nature, Published online: 10 June 2026; doi:10.1038/s41586-026-10633-1

Linafexor is a rapidly cleared FXR agonist designed to mimic natural bile acid signalling, achieving transient receptor activation with strong efficacy and reduced toxicity in preclinical and early clinical studies.
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Enabling superior high-temperature capacitive performance in polymer dielectrics by multifunctional alternating nanolaminate coating

Energy Environ. Sci., 2026, 19,3261-3270
DOI: 10.1039/D6EE00769D, Paper
Yuqi Liu, Jiufeng Dong, Kaixin Liu, Chengyuan Wang, Yujuan Niu, Liang Sun, Shuoyan Liu, Jiangyu Li, Jiannong Wang, Hong Wang
An alternating Al2O3/ZrO2 nanolaminate coating on polymers delivers a record discharged energy density of 8.50 J cm−3 with 96.4% efficiency at 150 °C via synergistic charge-injection blocking, deep trapping, and lateral electric field redistribution.
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