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Engineered TYK2 dependence enables myeloid-selective IL-10 receptor agonism

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11176-1

A tetravalent nanobody-based myeloid-selective IL-10 receptor agonist recapitulates IL-10’s potent suppression of monocytes, macrophages and dendritic cells while avoiding stimulation of T cells.
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Iron-mediated reversible lattice-oxygen redox enables stable 200 Wh kg<sup>−1</sup> sodium-ion batteries

Nature Energy, Published online: 20 August 2026; doi:10.1038/s41560-026-02112-8

Lattice-oxygen redox can raise the energy density of layered oxide cathodes, but poor reversibility causes structural degradation and capacity loss. Here the authors use iron as a bulk redox mediator to boost oxygen-redox reversibility and stabilize high-energy sodium-ion batteries.
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Stable tin–lead perovskite inks for efficient all-perovskite tandems

Nature Energy, Published online: 26 May 2026; doi:10.1038/s41560-026-02077-8

Low-bandgap tin–lead perovskites can boost solar cell efficiency but degrade quickly due to tin oxidation. Here the authors add proton-scavenging additives that stabilize inks for over 300 days, enabling 24.06% single cells and 29.56% certified tandem efficiency.
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