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Ubiquitous Kelvin–Helmholtz instabilities driving plasma mixing on the Sun

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10871-3

High-spatial-resolution observations of the solar photosphere reveal a far more complex and dynamic solar scene than previously observed and show that ubiquitous Kelvin–Helmholtz instabilities drive plasma mixing on the Sun.
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In situ particle-to-fibre transformation of hydrogels for 3D printing

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10883-z

A three-dimensional printing method transforms hydrogel particles into aligned microfibres during extrusion, creating structural anisotropy to accelerate muscle tissue regeneration.
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Amygdala astrocyte primary cilium mechanisms contribute to stress behaviours

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10874-0

Amygdala astrocyte primary cilia are disrupted during stress, and their restoration leads to improvements in stress-related behaviour in mice.
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A dependency map enhanced with next-generation 3D cancer models

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10843-7

Integration of genome-scale CRISPR screening data from traditional cell lines and next-generation cancer models expands the representation of tumour subtypes and genomic alterations in The Cancer Dependency Map.
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Upcycling of polyvinyl chloride into polyalphaolefin lubricants

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10867-z

A mild chemical process upcycles polyvinyl chloride waste into polyalphaolefin lubricants with tunable properties, offering an economical route to plastic recycling and improved carbon circularity.
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An entangling gate for dual-rail erasure qubits

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10822-y

A fast, low-error entangling gate for dual-rail cavity erasure qubits preserves a strong error hierarchy, advancing scalable quantum error correction with substantially improved fault-tolerant performance.
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Encapsulation epitaxy of air-stable 2D superconductors for quantum circuits

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10865-1

An ‘encapsulation epitaxy’ mechanism is used to grow air-stable, two-dimensional superconducting films at the interface of a 2D–3D hybrid substrate, holding promise for use in fabrication of superconducting quantum circuitry.
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Stimulation modulates gene-linked cell assemblies in the human brain

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10879-9

Stimulation of human cortex reorganizes neural assemblies and induces cell-type-specific gene regulatory programs, establishing an ex vivo framework that links stimulation parameters to circuit and transcriptional responses for designing targeted neuromodulatory therapies.
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A compendium of next-generation patient-derived models for diverse cancers

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10806-y

The international collaboration of the Human Cancer Models Initiative presents a comprehensive resource of next-generation cancer models from 2,780 donors with 25 cancer types and integrated tumour–model genomic, transcriptomic and epigenomic analyses.
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Antigen presentation by CD40<sup>+</sup>MHC-II<sup>+</sup> astrocytes promotes CNS autoimmunity

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10860-6

Astrocytes promote central nervous system (CNS) immunity through antigen presentation and activation of CD40 in astrocytes by CD40L expressed by CD4+ T cells in a model of experimental autoimmune encephalomyelitis.
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The Virtual Tissues foundation model resolves spatial proteomics across scales

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10884-y

Virtual Tissues (VirTues), a foundation model for spatial proteomics that captures tissue organization across scales, supports marker reconstruction, cell segmentation and typing, niche annotation, spatial biomarker discovery and patient stratification across heterogeneous panels and datasets.
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Virus reactivation in acute and long COVID-19

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10740-z

Chronic reactivation of distinct herpesviruses and anelloviruses occur during acute and long COVID-19, and track with disease severity, inflammation and outcomes, revealing immune signatures with prognostic potential.
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