Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10764-5

Towards Conversational AI for Disease Management

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10586-5

Analysis of long-term radial velocity data and transit time variations, induced by a super-Earth, a warm Jupiter and a brown dwarf in a coplanar orbit around the relatively young star TOI201.

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10638-w

A new polaritonic optical method that uses the mid-infrared out-of-plane hyperbolic polaritons mode is described and experimentally validated to allow the examination of picometre-scale interlayer deformations, providing a bridge between nanomechanics and photonics.

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10617-1

A prototype differential atom interferometer operates at the standard quantum limit with no excess noise beyond atom shot noise, achieving performance in line with the specifications for future long-baseline atom interferometers.

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10657-7

Cryo-electron microscopy and biochemical reconstitution experiments in yeast provide insight into the assembly of the CMGE complex, a helicase that establishes bidirectional DNA replication in eukaryotic cells, and elucidate the role of the firing factor Sld2.

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10676-4

A new quantum computer, Quantinuum Helios, which is a 98-qubit trapped-ion quantum processor built on the QCCD architecture, demonstrates performance well beyond classical capabilities and provides a path for scaling up quantum computing.

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10650-0

Biochemical, structural and cell biological analyses reveal that UAP56 (DDX39B) assembles with a TREX-2–like module that redirects non-functional polyadenylated RNAs from export to degradation.

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10664-8

Permafrost thaw on the Qinghai–Tibet Plateau increases rock-weathering rates while reducing river CO2 emissions, suggesting geological carbon fluxes may eventually outpace thaw-driven emissions.

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10679-1

Using single-nucleus multi-omic sequencing, diverse autism spectrum disorder-linked gene mutations converge on transient, stage-specific disruptions in early brain development, and highlight sex-specific gene expression alterations.

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10653-x

A comprehensive map of the human motor cortex at single-neuron resolution is described.

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10691-5

Wide-scale recordings reveal neurons in the human brain that encode fundamental components of language such as the grammatical relationships between words, their parts of speech and the higher-order syntactic structure of phrases and sentences.

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10675-5

A large language model artificial intelligence agent operating in a sandboxed electronic health record system can autonomously take patient histories, order tests, interpret findings, diagnose conditions and propose treatments, outperforming experienced clinicians while adhering to safety standards and clinical guidelines.

Nature, Published online: 16 June 2026; doi:10.1038/d41586-026-01916-8

Terms of endearment? Bias in first-name eponyms for species named after people

Nature, Published online: 11 June 2026; doi:10.1038/s41586-026-10784-1

Author Correction: Plasticity and language in the anaesthetized human hippocampus

Nature, Published online: 10 June 2026; doi:10.1038/s41586-026-10645-x

SIRT7 safeguards X-chromosome integrity and dosage balance with autosomes.

Nature, Published online: 10 June 2026; doi:10.1038/s41586-026-10631-3

Tumour network mapping of diffuse midline glioma (DMG) defines a conserved and prognostically important brain network in children with DMG, consistent with the hypothesis that DMGs exploit otherwise healthy brain circuits to promote tumour growth.

Nature, Published online: 10 June 2026; doi:10.1038/s41586-026-10538-z

The first data of the Jiangmen Underground Neutrino Observatory deliver high-precision neutrino oscillation parameters, improving measurements and demonstrating readiness to determine neutrino mass ordering.

Nature, Published online: 10 June 2026; doi:10.1038/s41586-026-10588-3

Mitochondria interact directly with the nuclear pore complex via VDAC1–RANBP2 binding to sustain nuclear ATP levels.

Nature, Published online: 10 June 2026; doi:10.1038/s41586-026-10628-y

Experimental demonstration of quantum error-correcting codes combined with error detection and post-selection applied to a trapped-ion quantum processor shows improvements in logical error rates ranging from 11× to 800× compared with several physical circuit baselines.

Nature, Published online: 10 June 2026; doi:10.1038/s41586-026-10555-y

A systematic review and analysis shows how user-centred design can be integrated into, and strengthen, co-production approaches for building user-driven climate adaptation products.