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A natural depsipeptide antibiotic binds the E-site of the bacterial ribosome

Nature, Published online: 03 June 2026; doi:10.1038/s41586-026-10589-2

Improved fractionation strategies can identify antibiotics with previously unseen scaffolds and mechanisms, exemplified by manikomycin from Streptomyces rimosus, which acts by targeting the E-site of the bacterial large ribosomal subunit.
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Mining triggers extensive additional deforestation in sub-Saharan Africa

Nature, Published online: 03 June 2026; doi:10.1038/s41586-026-10551-2

Extensive mining activity leads to large-scale deforestation of dense tropical forests across sub-Saharan Africa, driven particularly by key energy transition minerals such as cobalt.
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Cold-induced peptide signalling secures pollen resilience and crop yield

Nature, Published online: 03 June 2026; doi:10.1038/s41586-026-10603-7

A small-peptide signalling axis involving RGF family members controls resilience to cold stress in tomatoes and rice; modulating this pathway prevents cold-induced yield losses.
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Teosinte alleles enhance nitrogen assimilation and seed protein in maize

Nature, Published online: 03 June 2026; doi:10.1038/s41586-026-10575-8

Teosinte alleles enhance nitrogen assimilation and seed protein without lowering crop yield when expressed in modern maize, providing a powerful strategy for crop improvement to meet future population demands.
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