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Intestinal stem cells count self-renewal divisions to switch multipotency

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10814-y

In Drosophila, cell fate switching in adult intestinal stem cells is determined through an epigenetic mechanism in which these cells count divisions, switching from producing enterocytes to producing an enteroendocrine mother cell every ninth division.
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CRISPR–Cas regulates expression of embedded anti-phage defence systems

Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10833-9

CRISPR–Cas systems transcriptionally tune diverse innate defences using CRISPR RNA-like guides to balance antiviral protection with fitness, and hyperactivate these defences when compromised, establishing a layered bacterial ‘immunity guard’ network.
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Scalable quasi-pure MOF membranes for energy-efficient gas separations

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10655-9

Scalable quasi-pure metal–organic framework membranes achieve near-intrinsic separation performance, enabling energy-efficient industrial gas separations with major cost reductions compared with distillation.
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Perovskite–organic tandem solar cells with a photo-transformable stabilizer

Nature, Published online: 13 July 2026; doi:10.1038/s41586-026-10869-x

Perovskite–organic tandem solar cells with a photo-transformable stabilizer
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A 5.3-million-year-old deep-sea whale necropolis in the Diamantina Zone

Nature, Published online: 10 June 2026; doi:10.1038/s41586-026-10546-z

Researchers uncovered an enormous deep-sea accumulation of whale remains in the southeastern Indian Ocean, showing long-term, specialized ecosystems and an extensive fossil record that offers new insight into deep-ocean biodiversity and whale evolutionary history.
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