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Evidence for multi-Li<sup>+</sup> clustering in lithium-ion battery electrolytes

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11138-7

Machine-learning-enabled atomistic simulations, spectroscopy, electrochemical data and quantum-chemical calculations reveal previously unstudied multi-lithium-ion complexes without bound anions, improving understanding of lithium-ion-battery functionality at the atomic level.
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Engineered TYK2 dependence enables myeloid-selective IL-10 receptor agonism

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11176-1

A tetravalent nanobody-based myeloid-selective IL-10 receptor agonist recapitulates IL-10’s potent suppression of monocytes, macrophages and dendritic cells while avoiding stimulation of T cells.
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<i>Elp1</i> is required for myeloid differentiation and brain repopulation

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11112-3

Primary cultured haematopoietic stem and progenitor cells are used to analyse the molecular mechanisms of brain myeloid differentiation, and this platform enabled the identification of elongation factor ELP1 as an important regulator of this process.
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Modelling mouse embryogenesis from chemically induced totipotent stem cells

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11164-5

A mouse embryo model derived from chemically induced totipotent-like stem cells progresses through key developmental milestones, including gastrulation, embryonic axis formation, haematopoiesis and early organogenesis.
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