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Evidence for multi-Li<sup>+</sup> clustering in lithium-ion battery electrolytes

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11138-7

Machine-learning-enabled atomistic simulations, spectroscopy, electrochemical data and quantum-chemical calculations reveal previously unstudied multi-lithium-ion complexes without bound anions, improving understanding of lithium-ion-battery functionality at the atomic level.
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Engineered TYK2 dependence enables myeloid-selective IL-10 receptor agonism

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11176-1

A tetravalent nanobody-based myeloid-selective IL-10 receptor agonist recapitulates IL-10’s potent suppression of monocytes, macrophages and dendritic cells while avoiding stimulation of T cells.
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<i>Elp1</i> is required for myeloid differentiation and brain repopulation

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11112-3

Primary cultured haematopoietic stem and progenitor cells are used to analyse the molecular mechanisms of brain myeloid differentiation, and this platform enabled the identification of elongation factor ELP1 as an important regulator of this process.
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Competing mechanisms toughen bcc binary and medium-entropy alloys at 20 K

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11065-7

The mechanical properties of medium-entropy alloys at 20 K show a plateau in tensile yield strength and fracture toughness as a function of temperature, with no apparent ductile-to-brittle transition.
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Capillary-selective vasodilation through myosin inhibition halts ischaemic cascades

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11171-6

R(+)2501 reverses capillary no-reflow by relaxing pericytes, restoring microvascular perfusion and improving survival in animal models of myocardial infarction and acute kidney injury.
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