An experimental GLP-1 pill helped people with obesity or overweight lose as much as 12.1% of their body weight in just 36 weeks. Unlike injectable drugs such as Wegovy and Ozempic, aleniglipron is a small molecule that can be taken once daily with or without food and could potentially be produced more easily at scale.

Very high levels of the inherited cholesterol-related particle Lp(a) were linked to a greater risk of major cardiovascular events, particularly stroke and cardiovascular death, in a study of more than 20,000 people. Since elevated Lp(a) often flies completely under the radar, a simple blood test could uncover hidden heart risk that standard cholesterol testing may miss.

Silver nanocatalysts have been found to switch where they perform their most important reactions depending on whether a solid oxide cell is making electricity or hydrogen. The discovery could enable smarter catalyst designs that boost clean power generation while making green hydrogen more energy-efficient.

A 240-million-year-old reptile discovered in Brazil is revealing what evolution looked like just before the rise of dinosaurs and crocodiles. The small predator had unusually positioned legs that may have allowed it to move more efficiently than many earlier reptiles. Its close relatives were previously known mostly from other continents, suggesting these ancient animals spread much farther across the Triassic world than scientists realized.

The rise of the potato in the Andes appears to have left a lasting mark on human DNA. Indigenous Peruvians carry exceptionally high numbers of a starch-digestion gene, likely because people with more copies gained an evolutionary advantage once potatoes became a staple food. The change began thousands of years before European contact, providing unusually strong evidence that diet can shape human evolution.

A total solar eclipse will plunge parts of Europe into darkness on August 12, 2026, with Spain offering some of the best views. ESA will livestream the spectacle from the Javalambre Observatory, combining telescope feeds, drone footage, and expert commentary. At 20:31 CEST, the observatory will experience 1 minute and 21 seconds of totality, revealing the Sun’s normally hidden outer atmosphere.

NASA engineers have found a clever way to squeeze more life out of Voyager 2, nearly half a century after it left Earth. In an operation nicknamed the “Big Bang,” the team simultaneously shut down certain power-hungry hardware and switched to lower-power alternatives while keeping the spacecraft warm enough to survive.

Dogs have been shaping—and being shaped by—humans for about 15,000 years, evolving from early partners of hunter-gatherers into an astonishing range of specialized companions. Across the globe, they adapted alongside people to wildly different environments and needs, from powerful Arctic sled dogs and agile rainforest hunters to high-altitude dogs with genetic traits for surviving thin air. Some were even bred for wool, while others played important spiritual or ceremonial roles.

Cassini data has revealed a surprising twist in Saturn’s magnetic shield: the planet’s rapid rotation appears to drag a key opening in its magnetosphere far toward the afternoon side instead of keeping it near noon, as happens on Earth. The finding confirms that giant planets like Saturn operate under a fundamentally different magnetic regime, where fast spin and charged material from moons such as Enceladus can overpower the Sun’s influence.

A daily glass of 100% fruit juice or a smoothie may help improve more than just fruit intake. In a small four-week trial, participants who added one to a healthier diet showed significantly lower depression scores, hinting that a simple dietary change could also support mental well-being.

Just a couple of hours of strength training each week could have surprisingly powerful effects on longevity. People who lifted weights for around 90 to 120 minutes weekly had a 13% lower risk of dying early, with especially large reductions in deaths from cardiovascular and neurological diseases. Pairing strength training with regular aerobic exercise was even more impressive, lowering overall death risk by about 45%.

Frequent cannabis users may wake up with unusually high levels of the stress hormone cortisol, suggesting their daily stress rhythms could be disrupted. Researchers say the finding raises questions about whether using cannabis for stress relief might, over time, interfere with the very system that helps the body handle stress.

Full-fat dairy may be healthier than conventional advice has suggested. In a 12-week study, adults who ate three servings a day showed no meaningful increases in weight, body fat, cholesterol, or insulin resistance. They also experienced improved blood pressure and consumed more calcium, protein, and vitamin D. The findings suggest dairy’s complex structure may matter more than its saturated fat content alone.

More than 60,000 years ago, humans in southern Africa were engraving ostrich eggshells with intricate geometric patterns that appear far more organized than previously realized. Researchers found recurring grids, parallel lines, right angles, and repeated shapes, suggesting the designs followed deliberate rules rather than being improvised. The engravers may even have planned entire patterns in their minds before carving them.

Deep underground, bacteria may be capable of doing something remarkable: trapping toxic uranium before it spreads. When researchers fed microbes in uranium-contaminated mine water with glycerol, about 95% of the dissolved uranium disappeared within 130 days. The bacteria helped convert it into an unusually stable uranium compound that had rarely been observed before.

Chemists have developed a catalyst that breaks a long-standing rule governing which molecules receive electrons during chemical reactions. By releasing electrons directly into solution, the technique could unlock reactions—and potentially useful new molecules—that were previously out of reach.

Dinosaurs conquered the land at enormous sizes, but strangely, they almost never evolved into truly tiny animals. New research suggests that physiology alone can’t explain this missing miniature end of the dinosaur spectrum—and that early mammals may have been partly responsible. While dinosaurs kept mammals from becoming large, small mammals may have returned the favor by occupying ecological niches that could otherwise have supported mouse-sized dinosaurs.

A study tracking more than 340,000 adults for over a decade found that heavy drinking increased the risk of death regardless of beverage type. At lower levels, however, the picture became more surprising: beer, cider, and spirits were linked to higher mortality, while wine was associated with lower risk. Moderate wine drinkers had a 21% lower risk of cardiovascular death compared with people who rarely or never drank.

Atomically thin semiconductors could enable dramatically smaller and more efficient chips, but a stubborn problem at the boundary between materials has limited their performance. Researchers have now engineered that atomic interface to protect electron flow while still allowing extremely thin insulating layers. The resulting transistors delivered an unusually strong combination of electrical control and performance.

An intensive seven-day meditation retreat triggered striking changes across the brain and body, including shifts tied to neuroplasticity, immunity, metabolism, and natural pain relief. Participants also showed brain connectivity patterns resembling those associated with psychedelic experiences, suggesting that powerful altered states may be achievable without drugs.