❌

Reading view

Color-sensing yeast could make biofactories more programmable and precise

Baker's yeast is one of biotechnology's most important microorganisms. It has long been used to leaven bread and ferment beer. More recently, advances in synthetic biology have enabled engineered yeast to convert sugar into a wide range of products, including medicines, fuels and industrial chemicals. Yet even well-engineered yeast cells can be difficult to control in a precise and timely way.

  •  

Historical DNA reveals largetooth sawfish have lost much of their genetic diversity

The genetic diversity of the largetooth sawfish (Pristis pristis), a critically endangered ray, has plummeted over the past century and a half, according to a study published in the Proceedings of the Royal Society B: Biological Sciences. The species once lived in tropical waters worldwide but has disappeared from much of its former range.

  •  

Who are the secret gardeners of a parasitic plant?

In the coastal forests of a tropical Japanese island near Okinawa grows an inconspicuous plant that is easy to mistake for a mushroom. It is a non-green parasite that feeds on the roots of other plants and produces up to 1 million tiny seeds, each covered in a minuscule, dry fruit. The seeds, in particular, present a mystery to scientists: How do they get dispersed?

  •  

Machine learning predicts forest soil fungal diversity from drone images

Combining drone data and machine learning can help cover more ground in monitoring forest soil health, University of Alberta research shows. The findings are published in the journal Forest Ecology and Management. Using both tools to map and monitor soil fungal diversityβ€”a key indicator of a healthy forest ecosystemβ€”proved highly effective and could help reduce the need for boots-on-the-ground soil sampling over huge areas of forest, says Dr. Cameron Carlyle, a professor in the Faculty of Agricultural, Life & Environmental Sciences and a co-author of the study.

  •  

DNA repair enzymes favor specific sequences, shaping mutation patterns in the human genome

When a wound does not heal properly, it leaves a scar. Similarly, mutationsβ€”which are permanent changes to genetic codeβ€”are often the result of damaged DNA that has not been properly repaired. Mutations can impede the function of genes and lead to disease and aging, but they are also the source of genetic variation, which allows new traits to emerge and facilitates the evolutionary process. Scientists still do not fully understand why some damaged DNA segments are successfully repaired while others are not.

  •  

Engineered enzymes forge carbon-carbon and carbon-nitrogen bonds with high selectivity

Researchers from the Manchester Institute of Biotechnology, including Dr. Zachary Birch-Price and professor Anthony Green, have developed a new family of engineered enzymes that can create several different types of chemical bonds used to build complex molecules. This work demonstrates how artificial enzymes can be adapted to carry out a broad range of carbon-carbon (C-C) and carbon-nitrogen (C-N) bond-forming reactions with high selectivity, offering new possibilities for biocatalysis.

  •  

Photosynthetic microorganisms achieve long-lasting and renewable chemical production

Photosynthetic microorganisms can use light energy to convert carbon dioxide into useful compounds under mild, environmentally compatible conditions. However, many current photosynthetic production systems rely on cells growing freely in large volumes of liquid. This creates a substantial demand for water and requires extensive mixing to keep the cells evenly distributed and exposed to light, increasing the resource and energy requirements of the process.

  •  

Uncovering how Cryptococcus shifts from silent infection to killer fungus

For most healthy people, Cryptococcus is an unnoticed infection. The immune system walls it off in the lungs and keeps it dormant for life. But in patients undergoing cancer chemotherapy, recovering from an organ transplant, living with HIV or taking newer immunosuppressing drugs for autoimmune disease, the fungus can reactivate, spread to the brain and cause meningitis.

  •  

Fermentation emerges as key pathway for ammonium production beneath the Pearl River Delta

A study led by Professor Jimmy Jiujiu Jiao from the Department of Earth and Planetary Sciences at The University of Hong Kong (HKU) and Professor Meng Li from Shenzhen University has identified microbial fermentation as the likely main pathway for ammonium production in sediments beneath the Pearl River Delta, helping to explain the region's exceptionally high natural groundwater ammonium levels.

  •  

Quantum heat circuits learn electronics' oldest trick: Sharing a power supply

Every electronic and optoelectronic device generates heat, and today that heat is managed almost entirely from the outside. Heatsinks, fans, cold plates and refrigerators are bulky exterior measures bolted onto a chip or package after the fact. They treat heat as a single averaged quantity to be removed in bulk, even though the heat is actually produced locally, component by component, deep inside the circuitry.

  •  
❌