A new USC-led study finds Alzheimer's disease and related dementias will cost the United States an estimated $818 billion this year, driven largely by often-overlooked costs to persons living with dementia and family and friends providing their care.
Hidden costs push United States dementia toll to historic high
CADASIL, an inherited disease caused by mutations in the NOTCH3 gene, damages the brainβs small blood vessels, leading to strokes, cognitive decline, and early dementia.
Zebrafish model unlocks new insights into hereditary brain disease
Two research teams at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have developed a pioneering technique in Spain to characterize the proteome of individual cardiomyocytes-the cells responsible for heart contraction.
Pioneering technique maps the proteome of individual cardiomyocytes
A genetic difference carried by nearly one in three people may increase the risk of severe COVID-19 and lung fibrosis by disrupting the function of a previously unknown protein, according to a new study.
Common genetic difference may increase the risk of severe COVID-19 and lung fibrosis
An early view of the immune response to bacteria in the lungs provides clues as to why some people keep TB in check, while others develop disease, suggesting new ways to intervene earlier and stop TB.
Study reveals early immune clues to predict active tuberculosis risk
The conditions that could help women GPs build long and rewarding careers already exist, but they are routinely undermined in everyday practice, according to a new review led by the University of Surrey.
Addressing hidden burdens can help women GPs build rewarding careers
The World Health Organization (WHO) today calls on countries to expand newborn screening for birth defects, highlighting how early detection and treatment can save lives and reduce lifelong disability for millions of children.
WHO urges countries to expand newborn screening for birth defects
One of the world's most significant collections of plant specimens is under threat from the ongoing war in Ukraine, prompting an international call for urgent digitization and global collaboration to preserve an irreplaceable scientific resource.
Hidden botanical treasures in war-torn Kyiv need global support
Research indicates that long-term wholegrain intake per Nordic guidelines is associated with reduced breast cancer risk, emphasizing food type differences.
Eating 90 g of wholegrains daily linked to lower breast cancer risk
A 20-year study links plant-based Mediterranean diets to lower heart disease risk, highlighting the importance of sustainable eating for cardiovascular health.
Plant-based Mediterranean-style diet cuts heart disease risk by 26%
The link between biological aging and early-onset cancer risk offers crucial insights into generational health trends and potential preventive measures.
Faster biological aging may explain rising early-onset cancers
FairJourney Bio (βFJBioβ), a global antibody discovery expert, has entered a partnership with AbTherx, Inc. to bring transgenic mouse-based antibody discovery in-house. The agreement gives the Company access to AbTherxβs Atlasβ’ Full Human Diversity (FHD) and Common Light Chain (cLC) mouse technologies, completing a discovery route that partners can now run end to end entirely within FJBioβs integrated workflow.
FairJourney Bio and AbTherx partner to offer fully integrated antibody discovery
A scoping review of 140 empirical studies found that human-AI collaboration in healthcare reports the most consistent benefits in diagnostic interpretation, especially when AI supports bounded tasks and clinicians retain final responsibility. Evidence remains fragmented across triage, treatment planning, and documentation, with few studies measuring patient outcomes, system impact, trust calibration, or governance in real-world settings.
Human-AI teams improve healthcare only when clinicians stay in control
A systematic review and meta-analysis of 11 randomized controlled trials found that exercise during the post-weight-loss maintenance phase reduced weight regain by an average of 2.81 kg compared with control groups. Evidence for fat-mass reduction remained inconclusive, highlighting the need for longer, standardized trials with better adherence and body-composition monitoring.
Lost weight is less likely to return when exercise follows obesity treatment
A Korean target trial emulation found that starting antidiabetic medication within 12 months of newly crossing type 2 diabetes diagnostic thresholds was associated with lower five-year all-cause mortality. MACE risk was numerically lower with earlier treatment, but the reductions in cardiovascular events were not statistically significant, underscoring the need for larger studies.
Early diabetes drug treatment links to better survival after diagnosis thresholds
A 20-year prospective cohort study of 143,715 US healthcare professionals found that long-term resistance training was associated with a substantially lower risk of type 2 diabetes. The lowest risk was seen among participants who combined regular resistance training with adequate aerobic activity and limited TV viewing.
Strength training plus cardio cuts type 2 diabetes risk the most