This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology.

What’s at stake in AI’s trillion-dollar gamble

When Jessica Wachter, a finance professor at the University of Pennsylvania, wanted to assess AI’s impact on the economy over the next few years, she faced a long list of uncertainties. So she started with a “remarkable fact” that is not in question: a handful of so-called hyperscalers are investing huge amounts of money to build AI data centers.

Instead of trying to predict how widely deployed AI models will be, Wachter asked how fast the hyperscalers’ earnings will need to grow to justify their spending through 2027, when expenditures are expected to reach nearly $1.1 trillion.

The results are eye-opening. AI companies will need to achieve an extraordinary increase in productivity just to break even by 2030.

Take a closer look at what it will take for the AI buildout to pay off.

—David Rotman

AI models need more data about biology, and OpenAI is paying to create it

AI needs much more information to make important breakthroughs in curing disease. So last year Ruxandra Teslo, a policy analyst, posted an idea for supercharging medical AI systems: use data from failed biotech companies. By bidding at bankruptcy proceedings, she argued, it might be possible to obtain detailed regulatory filings, manufacturing strategies and safety data, creating what she called “biotech’s lost archive.” 

The OpenAI Foundation, the nonprofit parent of OpenAI, announced this week that it will fund her idea, paying to create “high-quality scientific datasets.”

Learn more about their new effort.

—Antonio Regalado

Our Roundables on AI’s extinction threat is now available on demand

As frontier models become more capable, warnings about AI extinction have become widespread in Silicon Valley. But are the threats really as dangerous as they’re presented?

In the latest MIT Technology Review Roundtable, executive editor Niall Firth, senior AI editor Will Douglas Heaven and AI reporter Grace Huckins took a closer look at the arguments behind those warnings. They discussed what AI extinction could actually mean, how seriously we should take the risks and what, if anything, can be done to reduce them.

Subscribers can now watch an exclusive recording of the discussion.

Want to join the next conversation? Subscribe to MIT Technology Review for exclusive access to all our future Roundtables, and recordings of previous ones.

MIT Technology Review Narrated: a startup claims it’s found a drug to make your blood young

Generation Lab says its new rejuvenation treatment “blocks the systemic spread of aging in the bloodstream, reawakens the body’s own repair mechanism, and restores health and youth to multiple tissues.”

The approach is based on research by the company’s scientific founder, Irina Conboy. She found that joining the circulatory systems of old and young mice improved the old animals’ ability to heal from injury.

Conboy now says she has found a combination of two existing drugs that can produce youthful effects without the need for any bodily fluid exchange. But there’s a snag: Generation Lab won’t reveal what the drugs are.

This is our latest story to become an MIT Technology Review Narrated podcast, which we publish each week on Spotify and Apple Podcasts. Just navigate to MIT Technology Review Narrated on either platform, and follow us to get all our new content as it’s released.

The must-reads

I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology.

1 Nvidia and Meta CEOs have rejected calls for a coordinated AI slowdown
Jensen Huang and Mark Zuckerberg pushed back on the proposals. (FT $)
+ Huang says new AI safety laws are unnecessary. (Axios)
+ Zuckerberg claimed competition will push AI labs toward safety. (Reuters $)
+ What’s next for AI after its doomer turn? (MIT Technology Review)

2 The FTC chair has warned against giving AI companies antitrust waivers
His comments follow Anthropic’s call for a safety exemption. (Reuters $)
+ Nvidia’s CEO also slammed the calls for new antitrust laws. (CNBC)
+ The US is divided over AI regulation. (MIT Technology Review)

3 A Chinese hacking firm has used AI to analyze stolen secret
Its tools turn hacked government data into intelligence reports. (WSJ $)

4 “Smart” nanoparticles delivered mRNA to tumors in a cancer study
The treatment reprogrammed cells to attack tumors in mice. (Wired $)
+ Federal health agencies are abandoning mRNA. (MIT Technology Review)

5 A digital fly brain is taking on an extraordinary range of tasks online
People have taught it to drive, trade bitcoin, and play Doom. (NYT $)
+ The simulated brain is a map of a fruit fly’s 166,000 neurons. (404 Media)

6 The Senate has blocked new crypto rules amid a fight over Trump
It demanded tougher ethics rules around Trump’s crypto holdings. (AP)
+ The move is a major blow to the crypto industry. (NYT $)

7 Chinese firms allegedly used Binance to launder Iranian oil money
Prosecutors say they laundered more than $1.5 billion. (Quartz)
+ Hackers are selling tools to bypass banks’ facial checks. (MIT Technology Review)

8 An AI agent platform is reinventing spam to flood inboxes worldwide
iLand says its agents have sent 1.6 million messages. (404 Media)

9 ByteDance founder Zhang Yiming has become Asia’s richest person
His fortune has risen above $105 billion as AI booms. (Bloomberg $)

10 A fully AI-generated sitcom has arrived—and it’s terrible
A reviewer called the characters “dead-eyed waxworks.” (Guardian)

Quote of the day

“The only institution that Americans might trust less than Washington these days is Silicon Valley.”

—Patrick Hillman, the chief operating officer of Logical Intelligence, a San Francisco–based startup chaired by Yann LeCun, says in a statement that people have little faith in tech companies to act in the public interest.

One more thing

Why Trump’s “golden dome” missile defense idea is another ripped straight from the movies

In 1940, a fresh-faced Ronald Reagan starred in Murder in the Air, a movie centered on a “superweapon” that could stop enemy aircraft. More than 40 years later, the concept became a real-life centerpiece of Reagan’s presidency with the Strategic Defense Initiative (SDI), better known as “Star Wars.” Now Donald Trump has revived the dream.

In 2024, Trump announced plans to build the “Golden Dome,” a system of sensors and interceptors on the ground, in the air and in space. It’s often compared to SDI for its futuristic sheen, its aggressive form of protection and the idea that an impenetrable shield is the cheat code to global peace.

The dream of a missile shield is animated by its sheer cinematic allure. But do cinematic spectacles actually enhance national security?

See what happens when the fantasy of missile defense meets reality.

—Becky Ferreira

We can still have nice things

A place for comfort, fun, and distraction to brighten up your day. (Got any ideas? Drop me a line.)

+ A once blind cockatoo just saw for the first time in 10 years.
+ Bingebrowse is a virtual video store stocked with films and shows from streaming services.
+ An amateur engineer has used a tree trunk to build Donkey Kong’s coconut gun as a real weapon.
+ A wildlife photographer has captured the first-ever images of the elusive and rare Cozumel dwarf fox.

The app is the best way to read, watch, and listen to WIRED’s journalism.

The app is the best way to read, watch, and listen to WIRED’s journalism.

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology.

The AI industry has taken a doomer turn. What now?

AI chiefs Dario Amodei, Sam Altman, Elon Musk, and Demis Hassabis are suddenly all in agreement: the latest generation of LLMs aren’t safe and everyone needs to figure out what to do about it. 

It’s easy to be cynical. With trillion-dollar IPOs in their sights, OpenAI and Anthropic need to reassure investors that they’re the grown-ups in the room while at the same time hinting at the power of the monsters they have created and intend to tame. Calling for a slowdown does both. 

Still, the vibe at the top of these firms really does appear to have shifted. But what does a slowdown actually mean, and how much should we trust the companies calling for one? 

Read the full story about what could come next.

—Will Douglas Heaven

This article is from The Algorithm, our weekly AI newsletter. Sign up to receive it in your inbox every Monday.

Roundtables: could AI really kill us all?

AI extinction fears have gone from a fringe idea to a serious concern among people working at the world’s leading AI labs. But how credible are those fears, and what should we make of the warnings?

Today, MIT Technology Review executive editor Niall Firth, senior AI editor Will Douglas Heaven and AI reporter Grace Huckins will unpack the debate in a subscriber-only Roundtable. They’ll look at where AI extinction fears come from, whether they hold any water and what we should do if they do.

Tune in today at 16:00 BST / 11:00am EST / 8:00am PST.

Want to join the conversation? Subscribe to MIT Technology Review for exclusive access to all our Roundtables.

AI agents blew the whistle on their cheating colleagues

A group of AI agents asked to solve a series of math problems split into rival factions—when some cheated, others tried to stop them. 

That whistleblowing behavior, seen for the first time in a recent experiment run by Google DeepMind, could have implications for alignment researchers trying to keep swarms of autonomous AI agents in line. 

The experiment offers a glimpse of how AI agents might police one another. But it also shows how quickly things can go off the rails when they’re left to interact on their own.

Find out what happens when AI agents start enforcing their own rules.

—Amit Katwala

Donated livers can be made biologically younger

Once an organ is removed from a donor’s body, the clock starts ticking. Surgeons usually flush it with a preservative solution, bag it and put it on ice, where it immediately starts to degrade. The team has a matter of hours to get it into a recipient’s body.

But there’s another option: machines that pump donated organs with nutrients and remove waste products, essentially giving them a chance to be back in a body. Now, scientists have found that livers kept on these systems seem to get younger, at least at a molecular level.

The finding could help explain why organs kept on these machines tend to do better after transplantation. It could also lead to new ways to test the health of donated organs and potentially repair ones that might otherwise be discarded.

Here’s what scientists discovered about making donated livers biologically younger.

—Jessica Hamzelou

The must-reads

I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology.

1 Trump has called AI safety fears a “hoax” and rejected more safeguards
He says stronger guardrails could undermine America’s AI advantage. (NBC)
+ Trump has united against AI doomerism with Nvidia’s Jensen Huang. (Axios)
+ Anthropic’s co-founder says AI kill switches may need to be mandatory. (BBC)
+ Bill Gates says we’ve passed AI’s risk thresholds. (MIT Technology Review)

2 OpenAI contractors are reading people’s ChatGPT chats 
And you can bet the vast majority of its 900 million users haven’t got a clue. (404 Media)
+ LLMs could supercharge mass surveillance. (MIT Technology Review)

3 The US military has confirmed it has weapons in orbit
It’s the first time the Pentagon has disclosed this. (Ars Technica)
+ Officials have not disclosed what the weapons are. (BBC)

4 A new brain implant can translate speech and gestures at the same time
The system converts brain activity into words and avatar movements. (Nature)
+ It helps people with paralysis communicate more naturally. (New Scientist $)
+ Eventually, they could control robots or exoskeletons. (Economist $)
+ China has approved the first invasive BCI. (MIT Technology Review)

5 New York has seized a dozen celebrity deepfake websites
It’s the biggest-ever legal action against harmful deepfake sites. (CNN)
+ Deepfakes have targeted at least 138 women MEPs. (Wired $)

6 US environmental regulators are scrapping limits on power plant emissions
The move could lead to dirtier power amid surging AI demand. (Verge)
+ Trump’s EPA says the rollback will save hundreds of billions. (Gizmodo)
+ New technology is changing nuclear power. (MIT Technology Review)

7 The EU plans to restrict social media and AI chatbots for kids
Under-15s would require parental supervision. (Politico)
+ The rules would also cover video platforms and games. (Reuters $)

8 Chinese researchers have mapped a path to the “last AI built by humans”
Their five-stage plan aims for genuine recursive self-improvement. (SCMP)
+ But it might take a while to get there. (MIT Technology Review)

9 The real AI economy is being built by ordinary people
Workers are using cheap AI to expand what they can do. (Rest of World)

10 Two strange new forms of ice could exist inside Uranus and Neptune
They could help explain the planets’  magnetic fields. (New Scientist $)

Quote of the day

“The only control or ‘guardrails’ that AI needs is a STRONG AND SMART (High IQ!) PRESIDENT, and the U.S.A. has that, in spades!”

—President Trump proclaims in a social media post that he’s the only protection that the US needs from AI.

One more thing

How creativity became the reigning value of our time

—Bryan Gardiner

Americans don’t agree on much these days, but there remains at least one quintessentially modern value we can all still get behind: creativity. We teach it, measure it, envy it and endlessly worry about its death.

Given how much we obsess over it, creativity can feel like something that has always existed. But the concept is surprisingly young. The first known written use of the word didn’t occur until 1875, and before about 1950 there were “approximately zero” articles, books, or essays dealing explicitly with the subject.

In his book The Cult of Creativity, Samuel Franklin explores how creativity became an unimpeachable value and why tech leaders have embraced it so enthusiastically. I spoke to him about why we’re so fascinated by creativity, how Silicon Valley became the supposed epicenter of it, and how AI might reshape our relationship with it.

Read the full interview.

We can still have nice things

A place for comfort, fun, and distraction to brighten up your day. (Got any ideas? Drop me a line.)

+ It took five days and 19,000 marbles to build this astonishing marble run.
+ Zero the Border Collie turns into a whole zoo with these adorable animal masks.
+ The Grainydays YouTube channel presents beautifully shot adventures in film photography.
+ Scientists have created an interactive map of underground fungi networks long enough to reach the sun a billion times.

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology.

Roundtables: could AI really kill us all?

Employees at the world’s leading AI labs are saying there’s a real possibility that advanced AI could destroy humanity. Are they right? Or is this more scaremongering and hype?

Join MIT Technology Review executive editor Niall Firth, senior AI editor Will Douglas Heaven, and AI reporter Grace Huckins for a subscriber-only conversation unpacking the debate around AI extinction. They’ll explore where the fears come from, whether they hold any water and, if they do, what we should do about them.

Register now to attend on Tuesday, September 15 at 16:00 BST / 11:00am EST / 8:00am PST.

Want to join the conversation? Subscribe to MIT Technology Review for exclusive access to all our Roundtables.

This geneticist’s age-reversal tech could help restore sight

Yuancheng (Ryan) Lu is obsessed with aging. And with eyes. As he steps outside the Whitehead Institute in Cambridge, Massachusetts, his aviator glasses darken automatically in the sun. Age-related blindness runs in his family, and his own 23andMe test came back with a mutation for macular degeneration, a top cause of vision loss in old age.

That obsession extends to his work. Lu is behind one of the coolest results in rejuvenation science and eye research: an age-reversal technique called reprogramming that repaired the optic nerves of blind mice, restoring their vision. Now, nearly the same genetic therapy he developed as a student has entered human clinical trials.

Learn more about Lu’s work on restoring sight with age-reversal therapy.

—Antonio Regalado

Yuancheng (Ryan) Lu is one of the biotechnology and health honorees on our 35 Innovators Under 35 list for 2026. Meet the rest of them here, or explore the full list across the biotechnology and health, AI, computing and robotics, and climate and energy categories.

The must-reads

I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology.

1 Dario Amodei, Sam Altman, and Elon Musk have called for an AI slowdown
In a rare show of unity, the rivals agreed that AI needs stronger brakes. (Guardian) 
+ Amodei wants independent monitors and new industry-wide rules. (BBC)
+ Altman called for pacing, but not stopping. (Bloomberg $)
+ While Musk said on X that “Dario is right.”(WSJ $)
+ AI-linked stocks slumped in response. (FT $)
+ Chinese state media blasted the calls as a “Cold War” tactic. (Reuters $)
+ AI’s impacts are getting harder to predict. (MIT Technology Review)

2 Trump and Congress are resisting calls for stronger AI regulation
Trump downplayed AI risks, prioritizing the AI race with China. (NPR)
+ While the House Speaker said Congress won’t lead on AI regulation. (Politico $)
+ But Democrats are pushing for new rules before the midterms. (CNBC)
+ States and the White House are dividing over AI. (MIT Technology Review)

3 China plans to lead AI development across the BRICS countries
President Xi proposed open-source AI cooperation. (CNBC)
+ Beijing’s spy agency has warned of AI threats to national security. (FT $)

4 South Korea has tightened espionage laws to protect its chip secrets
Foreign spies can now face up to 30 years in prison. (FT $)
+ The changes follow alleged transfers of Samsung tech to China. (Reuters $)

5 The US and Mexico are teaming up to zap drones at the border
The operation may employ high-energy lasers.(Wired $)
+ Ukraine is a Wild West market for drone data. (MIT Technology Review)

6 AI agents are creating a new problem for the criminal justice system
The law has no clear answer when AI agents act independently. (Bloomberg $)
+ While courts face a flood of AI-generated lawsuits. (MIT Technology Review)

7 A Waymo pulled over and alerted police after detecting a gun
The riders were juveniles carrying a loaded AR-style ghost gun. (LA Times $)

8 Meta has been sued over data used to train its smart glasses
It allegedly used Facebook and Instagram photos without consent. (Wired $)

9 A hidden crypto farm in Mexico has put a spotlight on cartel funding
Authorities are investigating whether it stole power from a nearby dam. (Reuters $)

10 StarCraft is returning in 2030 as an open-world shooter
Fifteen years since its last release, the iconic franchise will be reborn. (Verge)

Quote of the day

“Dr. Frankenstein is telling us the monster is escaping; help us stop this.”

—Sen. Ruben Gallego, D-Ariz, calls for new AI regulation on CNN’s “State of the Union.”

One more thing

Inside the hunt for the most dangerous asteroid ever 

As asteroid 2024 YR4 hurtled toward Earth, astronomers determined that this massive rock posed a higher risk of impact than any object of its size in recorded history. Then, just as quickly as history was made, experts declared that the danger had passed. 

This is the inside story of the network of global scientists who found, followed, planned for, and finally dismissed the most dangerous asteroid ever found—all under the tightest of timelines and with the highest of stakes. Find out how they did it. 

—Robin George Andrews

We can still have nice things

A place for comfort, fun, and distraction to brighten up your day. (Got any ideas? Drop me a line.)

+ This master paperboy delivers newspapers with astonishing speed and skill.
+ Public Enemy and Led Zeppelin collide in this gloriously unlikely musical mashup.
+ Dozens of synchronized lasers have created extraordinary kaleidoscopic starburst patterns.
+ Check out the breathtaking winning images from the 2026 International Aerial Photographer of the Year competition.