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Received — 17 June 2026 ⏭

Molecular basis of polyadenylated RNA fate determination in the nucleus

✇Nature
By: Andrii Bugai · Ulrich Hohmann · Ana Lorenzo · Max Graf · Laura Fin · Jérôme O. Rouvière · Laszlo Tirian · Yuhui Dou · Marion Le Rest · Patrik Polák · Dennis Johnsen · Lis Jakobsen · Jens Skorstengaard Andersen · Julius Brennecke · Clemens Plaschka · Torben Heick Jensen
17 June 2026 at 01:00

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10650-0

Biochemical, structural and cell biological analyses reveal that UAP56 (DDX39B) assembles with a TREX-2–like module that redirects non-functional polyadenylated RNAs from export to degradation.
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