Normal view

Received — 3 June 2026 ⏭

Nature
Spermine is an endogenous iron chelator that inhibits ferroptosis 3 June 2026 at 01:00

Spermine is an endogenous iron chelator that inhibits ferroptosis

By: Man Li · Xuexin Yu · Shuqin Ouyang · Xiaohong Chen · Huiqi Yu · Yuanji Liu · Ziwen Li · Chunhua Yu · Rui Kang · Christine Gaillet · Ludovic Colombeau · Raphaël Rodriguez · Libing Song · Guido Kroemer · Daolin Tang · Jun Li

3 June 2026 at 01:00

Nature, Published online: 03 June 2026; doi:10.1038/s41586-026-10597-2

A non-canonical metabolic route for spermine synthesis mediated by ALDH18A1 limits iron availability and lipid peroxidation in hepatocellular carcinoma.

Nature
Centromeric footprints preserve telomere integrity in ALT cancers 3 June 2026 at 01:00

Centromeric footprints preserve telomere integrity in ALT cancers

Nature

3 June 2026 at 01:00

Nature, Published online: 03 June 2026; doi:10.1038/s41586-026-10598-1

Centromeric DNA repeat insertions and CENP-A chromatin assembly are identified as genomic signatures that preserve telomere integrity in ALT cancer cells.