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Normal view

Sequential reading of a stepwise-shortened peptide immobilized on nanopore

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10881-1

A nanopore-based ‘chop and measure’ method sequences peptides at single-amino-acid resolution by using enzymatic digestion to progressively shorten the N terminus one residue at a time, together with repetitive N-terminus re-reading.

Spatial distribution of the proteome in the human body and in cancers

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10660-y

A spatially resolved map of the human proteome across a variety of healthy tissues and cancers provides wide-ranging insights in developmental biology and oncology, and could aid the identification of therapeutic targets and development of treatments for cancer.
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