In a widely expected move, a committee organized by the Food and Drug Administration (FDA) has voted to endorse removing restrictions on the manufacture of peptides for human use. Thursday's panel meeting saw a sharply divided group recommend lifting limits on four peptides; votes on three additional peptides are scheduled for today. The move comes despite a continuing lack of evidence regarding their safety and effectiveness.

The move had been telegraphed months earlier as peptide enthusiast and Health and Human Services Secretary Robert F. Kennedy Jr. took steps to ensure this outcome.

Like proteins, peptides are composed of amino acids that are chemically linked into a chain. Peptides differ merely by length; they're often 10–20 amino acids long, in contrast to proteins, which can be hundreds or thousands. Some of them, such as insulin, are specifically made by targeted processing of a protein into shorter fragments, and the resulting peptide interacts with receptors that have evolved to send signals to cells based on its levels.

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Influencers peddle injectable shortcuts while regulators confront a fast-growing gray market.

The Food and Drug Administration announced on Wednesday that it's investigating yet another outbreak of Cyclospora, the unicellular foodborne parasite behind a nationwide surge in explosive watery diarrhea illnesses. The FDA said 72 cases have been identified in this outbreak, but the agency provided no details on the situation.

This announcement marks the sixth Cyclospora outbreak investigation the FDA has opened this year. Overall, the Centers for Disease Control and Prevention has gotten reports of more than 11,500 cases (including 4,173 confirmed and over 7,400 probable) from 41 states. Among the cases, there have been 308 hospitalizations and no deaths.

This year's tally so far—just in July—greatly exceeds the normal number of cases the US sees in a whole year. In recent years, the US has reported between 2,000 and 5,000 cases in a year, according to CDC data. With a new outbreak announced, the tally of cases is likely to continue climbing. Nevertheless, when asked about the national surge in cases earlier this week, anti-vaccine Health Secretary Robert F. Kennedy Jr. said the situation was "under control."

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Federal officials on Friday announced that shredded iceberg lettuce imported from Mexico and served at Taco Bell restaurants in five states is a source of Cyclospora, the foodborne parasite causing the nationwide surge in cases of explosive, watery diarrhea. The five states are Indiana, Kentucky, Michigan, Ohio, and West Virginia.

A traceback investigation by the Centers for Disease Control and Prevention and the Food and Drug Administration identified a single supplier in Mexico as the source of iceberg lettuce for Taco Bell restaurants where sick people reported eating. While federal authorities did not name the supplier, sources told the Washington Post that it is Taylor Farms.

Taylor Farms was also implicated in a 2024 multi-state E. coli outbreak linked to contaminated onions served at McDonald's and other fast-food restaurants. At the time, FDA inspectors found multiple violations at a Taylor Farms facility in Colorado.

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In an extremely odd case, a single 79-year-old patient was granted early access to Eli Lilly's powerful, still-experimental obesity drug retatrutide through the Food and Drug Administration's "compassionate use" program—raising immediate questions if that sole patient is President Donald Trump, according to a report by Stat News.

Lilly's retatrutide is a highly anticipated next-generation obesity drug that targets GIP and glucagon hormones in addition to GLP-1. It is currently in late-stage trials to treat obesity, diabetes, sleep apnea, and other conditions. Data from a Phase 3 trial that Lilly released in May indicates that patients with obesity (but without diabetes) who took the drug for 80 weeks lost 28 percent of their weight, an amount comparable to bariatric surgery.

Millions of Americans with obesity are eager to get the drug, with options being limited so far to enrolling in a clinical trial or trying to obtain it by dodgy methods.

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Il nuovo vaccino antinfluenzale mRNA di Moderna mostra risultati promettenti nella protezione contro l'influenza, con approvazione in arrivo.

Independent advisors for the Food and Drug Administration on Friday voted 9–0 in support of approving Moderna's seasonal mRNA flu vaccine, which a Trump appointee at the agency initially tried to block from even being reviewed.

In an all-day meeting, members of the FDA's advisory committee—known as VRBPAC for Vaccines and Related Biological Products Advisory Committee—pored over data and presentations on the vaccine, which is dubbed mRNA-1010 and branded as mFlusiva. The presentations included a review from FDA scientists, which was supportive of the vaccine.

Data from a Phase 3 trial including over 40,000 adults age 50 and older found the mRNA vaccine was around 27 percent more effective against seasonal flu than a standard flu shot. A smaller Phase 3 trial, involving data from nearly 3,000 people age 65 years and older, showed the shot produces stronger immune responses than a high-dose flu vaccine, which is recommended for this age group. The safety profile of the vaccine was also generally good.

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The Food and Drug Administration this week cleared a second carcass-feasting fly species for use in maggot wound therapy, according to an announcement from Cuprina Holdings, a Singapore-based company that has dubbed its new therapeutic larvae MediFly Maggots.

With the clearance, Cuprina appears to be the only company to have FDA clearance to sell two species of fly larvae—and it's abuzz with the potential to dominate the global maggot market.

The new species is Lucilia cuprina, or Australian sheep blowfly. It's a close relative of Lucilia sericata, or the common green bottle fly, which is the fly species most often used for wound therapy, often called biosurgery or maggot debridement therapy (MDT). L. sericata is the only other fly with FDA clearance, which the agency first granted in 2004 to Ronald Sherman, who is now Cuprina’s Medical and Scientific Director.

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A gene therapy for Huntington's disease has a new path toward approval from the Food and Drug Administration after the ouster of several Trump officials, particularly Vinay Prasad, who rejected the therapy in a shocking move one former FDA official called "truly evil."

Huntington's disease is an inherited condition that typically strikes in middle age and causes nerve cells in the brain to gradually break down. There are currently no treatments for the disease, and many afflicted die in their 50s and 60s.

Gene therapy company UniQure developed a one-time treatment, AMT-130, that aims to lower brain levels of the mutant protein behind the disease, called huntingtin. Data from a small, early trial suggested the drug could slow the progression of the disease up to 75 percent, and patients and advocates have closely watched the drug's development in hopeful anticipation.

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