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Received — 10 June 2026 ⏭

Nature
A first-in-class pulsatile FXR agonist for bile-acid-related liver diseases 10 June 2026 at 01:00

A first-in-class pulsatile FXR agonist for bile-acid-related liver diseases

By: Yi Zang · Jingjing Shi · Guanguan Zhao · Bixi Tang · Mingliang Liu · Benqiang Yao · Gaihong Wang · Hualing Pan · Shengsheng Yang · Rong Deng · Yishuang Zhao · Zhenwei Zhang · Hao-Ran Guo · Dan-Dan Sun · Hanlin Wang · Lixin Gao · Jinghua Yu · Xingxing Diao · Yong Li · Jia Li · H. Eric Xu

10 June 2026 at 01:00

Nature, Published online: 10 June 2026; doi:10.1038/s41586-026-10633-1

Linafexor is a rapidly cleared FXR agonist designed to mimic natural bile acid signalling, achieving transient receptor activation with strong efficacy and reduced toxicity in preclinical and early clinical studies.

Received — 31 May 2026 ⏭

RSC - Energy Environment
Efficient and stable electrochemical carbon capture via integrated CO2 absorption and regeneration 14 May 2026 at 00:00

Efficient and stable electrochemical carbon capture via integrated CO2 absorption and regeneration

RSC - Energy Environment

By: Zhiwei Fang · Junwei Zhang · Peng Zhu · Zhou Yu · Ahmad Elgazzar · Juan Wang · Wei Ping Lam · Haotian Wang

14 May 2026 at 00:00

Energy Environ. Sci., 2026, 19,3956-3967
DOI: 10.1039/D6EE01132B, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Zhiwei Fang, Junwei Zhang, Peng Zhu, Zhou Yu, Ahmad Elgazzar, Juan Wang, Wei Ping Lam, Haotian Wang
Integrated electrochemical CO₂ capture combining absorption and in situ regeneration enables bicarbonate-dominated operation, reduced pH overpotentials, low-energy, and >1000 h stable carbon capture from dilute gas streams.
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