A vitamin D-based therapy may help remodel the protective barrier surrounding pancreatic tumors, offering a potential new treatment strategy. Pancreatic cancer is notoriously difficult to treat in part because tumors surround themselves with a dense, protective barrier that blocks drugs and suppresses immune activity. Now, a small clinical trial led by researchers at Dana-Farber Cancer [...]

A new evolutionary analysis suggests that modern blood and immune cells may preserve a 700-million-year legacy inherited from ancient single-celled ancestors. Long before humans, dinosaurs, or even fish existed, ancient single-celled organisms may have already carried the genetic blueprint for one of the body’s most important systems: blood. A new study from Kyoto University suggests [...]