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De novo design of cysteine proteases

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11143-w

De novo-designed enzymes use an activated cysteine nucleophile to hydrolyse polypeptide backbones in a sequence-dependent manner.

Computational design of metalloproteases

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11167-2

RFdiffusion methods are used to de novo design proteins with water-activating zinc-based active sites adjacent to a peptide substrate binding pocket, yielding highly active, programmable proteases with potential applications in therapeutics, biotechnology and bioremediation.

Chrome for iPhone beta lets you ask Gemini about multiple open tabs

By: Venkat
24 July 2026 at 05:02

Google is testing a new Gemini feature in Chrome for iPhone. The latest Chrome for iOS TestFlight beta adds a Tabs option to the Ask Gemini prompt, letting users select multiple recent pages and ask Gemini questions across them without leaving the browser. This builds on the Ask Gemini button Google has already been testing […]

The post Chrome for iPhone beta lets you ask Gemini about multiple open tabs appeared first on The Mac Observer.

Conformal hetero-electrolyte interface between soft oxyhalides and garnet enables low-pressure lithium-reservoir-free solid-state batteries

Energy Environ. Sci., 2026, 19,3283-3299
DOI: 10.1039/D5EE07777J, Paper
Open Access Open Access
Max Palmer, Vipin K. Singh, Leonardo Merola, Karthikeyen Natarajan Pugazhendhi, Pallab Barai, Insang You, Yubo Wang, Eric Carlson, Cathy Wang, Hao Zheng, Venkat Srinivasan, Jürgen Janek, Jeff Sakamoto, Linda F. Nazar
Soft oxyhalide electrolytes enable low hetero-electrolyte (H-E) resistance with garnet at low stack pressures for “reservoir-free” dual electrolyte batteries.
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