Nature Energy, Published online: 20 October 2026; doi:10.1038/s41560-026-02148-w

Cathode interlayers play a pivotal role in improving the performance of organic solar cells. Yao, Zhang, Zhang, Wang et al. show a stepwise solvent treatment to achieve a vertically aligned cathode interlayer, enabling a certified efficiency of 20.65% in binary organic solar cells.

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11143-w

De novo-designed enzymes use an activated cysteine nucleophile to hydrolyse polypeptide backbones in a sequence-dependent manner.

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11167-2

RFdiffusion methods are used to de novo design proteins with water-activating zinc-based active sites adjacent to a peptide substrate binding pocket, yielding highly active, programmable proteases with potential applications in therapeutics, biotechnology and bioremediation.

Nature, Published online: 07 September 2026; doi:10.1038/s41586-026-11094-2

Author Correction: A mouse brain stereotaxic topographic atlas with isotropic 1-μm resolution

Nature, Published online: 08 July 2026; doi:10.1038/s41586-026-10712-3

Viscoelastic phase separation is used to fabricate non-collapsible, air-rich networks in high-water-content hydrogels containing silica aerogel beads, allowing air to permeate through the material and enabling a tenfold increase in oxygen permeability over pristine hydrogels.

Nature, Published online: 10 June 2026; doi:10.1038/s41586-026-10596-3

Efficient blue perovskite light-emitting diodes with an external quantum efficiency of 21.8% are achieved through in situ polymerization-driven nanocrystal confinement.