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Membranolytic peptide programs immunogenic cell death for cancer therapy

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10899-5

The synthetic-acid-responsive membranolytic peptide aMPC16-CA50 induces immunogenic membranolytic cell death in tumour cells, robustly potentiating immune checkpoint blockade therapy.

Confined migration induces non-lethal DNA damage in developing neurons

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10648-8

The migration of neurons in developing cerebral and cerebellar cortices is accompanied by massive DNA double-strand breaks due to mechanostress during passage through narrow interstitial spaces.

Stable tin–lead perovskite inks for efficient all-perovskite tandems

Nature Energy, Published online: 26 May 2026; doi:10.1038/s41560-026-02077-8

Low-bandgap tin–lead perovskites can boost solar cell efficiency but degrade quickly due to tin oxidation. Here the authors add proton-scavenging additives that stabilize inks for over 300 days, enabling 24.06% single cells and 29.56% certified tandem efficiency.
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