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Received — 10 June 2026 ⏭

A first-in-class pulsatile FXR agonist for bile-acid-related liver diseases

✇Nature
By: Yi Zang · Jingjing Shi · Guanguan Zhao · Bixi Tang · Mingliang Liu · Benqiang Yao · Gaihong Wang · Hualing Pan · Shengsheng Yang · Rong Deng · Yishuang Zhao · Zhenwei Zhang · Hao-Ran Guo · Dan-Dan Sun · Hanlin Wang · Lixin Gao · Jinghua Yu · Xingxing Diao · Yong Li · Jia Li · H. Eric Xu
10 June 2026 at 01:00

Nature, Published online: 10 June 2026; doi:10.1038/s41586-026-10633-1

Linafexor is a rapidly cleared FXR agonist designed to mimic natural bile acid signalling, achieving transient receptor activation with strong efficacy and reduced toxicity in preclinical and early clinical studies.

A kinetic descriptor of solvent polarization for rational electrolyte design in lithium–metal batteries

✇RSC - Energy Environment
By: Xilin Liang · Lingyan Duan · Qing Liu · Qi An · Hanlin Tang · Mou Yang · Hongjia Liu · Ou Ka · Yongxin Yang · Guiquan Zhao · Yongjiang Sun · Xiaomin Yang · Hong Guo
10 June 2026 at 00:00

Energy Environ. Sci., 2026, Advance Article
DOI: 10.1039/D6EE01727D, Paper
Xilin Liang, Lingyan Duan, Qing Liu, Qi An, Hanlin Tang, Mou Yang, Hongjia Liu, Ou Ka, Yongxin Yang, Guiquan Zhao, Yongjiang Sun, Xiaomin Yang, Hong Guo
A kinetic descriptor of solvent polarization unifies bulk transport and interfacial stability, enabling rational electrolyte design.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Received — 31 May 2026 ⏭

Enhancing redox flow battery performance across wide temperature ranges: mechanisms, challenges, and optimization strategies for electrodes, membranes, and electrolytes

✇RSC - Energy Environment
By: Xu Lin · Meisheng Han · Haolin Ju · Hengyuan Hu · Wanqi Hu · Jiajie Luo · Lei Wei · Lin Zeng · Wenjia Li · Tianshou Zhao
21 April 2026 at 00:00

Energy Environ. Sci., 2026, 19,3074-3099
DOI: 10.1039/D6EE00030D, Review Article
Xu Lin, Meisheng Han, Haolin Ju, Hengyuan Hu, Wanqi Hu, Jiajie Luo, Lei Wei, Lin Zeng, Wenjia Li, Tianshou Zhao
Failure mechanisms of redox flow batteries under wide-temperature conditions (>45 °C or <10 °C), with optimization strategies for electrodes, membranes, and electrolytes, and a future perspective on AI-assisted design.
The content of this RSS Feed (c) The Royal Society of Chemistry
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